Tenofovir, yomwe imatchedwanso tenofovir disoproxil fumarate, ndi mankhwala osokoneza bongo pofuna kuchiza matenda a chiwindi (B) omwe ali ndi zaka khumi ndi ziwiri (12) kapena kuposa. Amagwiritsidwanso ntchito, kuphatikiza ndi mankhwala ena, kuti athetse kachilombo ka HIV kapenanso kachilombo ka HIV . Ikugulitsidwa pansi pa dzina la Viread ndi Gileadi Sciences, Inc.
Momwe Ikugwirira Ntchito
HBV ndi tizilombo toyambitsa matenda, zomwe zimatanthawuza kuti kachilombo kawomwe sikangowononga chiwindi.
M'malo mwake, pamene thupi liri ndi kachilombo ka HIV, chitetezo cha mthupi chimayambitsa chiwopsezo chotenga kachilomboka ndipo chimayambitsa kuwonongeka kwa mtundu wa kutupa ndi kuwonongeka kwa chiwindi. Tenofovir ndi gawo la mankhwala omwe amatchedwa nucleoside reverse transcriptase inhibitors ( NRTIs ). Izi zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka hepatitis B m'magazi, zomwe zimathandiza kuti chitetezo cha mthupi chitetezeke. Sichidzachiza matenda a chiwindi cha mtundu wa B, sichidziteteza ku matenda monga chiwindi cha chiwindi kapena khansa ya chiwindi, ndipo sichiteteza ena ku chiwindi.
Maina Ena a Tenofovir
Palibe mankhwala achibadwa omwe alipo.
Mphamvu
Tenofovir imatha kuchiza matenda a hepatitis B molimbika kwambiri kwa anthu ena. Nthawi zina, tenofovir imagwira ntchito kuposa adefovir ndi lamivudine. Kafukufuku waposachedwapa amasonyeza kuti tenofovir ndi mankhwala otetezeka kwa nthawi yaitali kwa HBV, makamaka kwa anthu amene ayamba kutsutsa lamivudine.
Kuonjezera apo, kafukufukuyu akusonyeza kuti zotsatira zake zimakhala ndi zotsatira zochepa za impso ndipo palibe mankhwala okhudzana ndi mafupa.
Momwe Mungatengere Izo
Viread ndi piritsi 300 mg. Kudwala matenda a chiwindi a B, omwe nthawi zambiri amadwala akuluakulu ndi 300 mg kamodzi pa tsiku ndipo amatha kutengedwa kapena opanda chakudya. Mlingo uwu ukhoza kusintha kwa anthu omwe ali ndi mavuto a impso.
Ndalama
Chaka chimodzi chithandizo cha mankhwala a tenofovir chimatha mtengo woposa $ 8,000. Komabe, ndalama za mankhwala zimasiyana mosiyana ndi zinthu zambiri, monga ngati muli ndi inshuwalansi , komwe mukukhala komanso mankhwala omwe mumagwiritsa ntchito.
Zotsatira Zotsatira
Zotsatira zotheka za tenofovir ndizo:
- Kutsekula m'mimba
- Mutu
- Kusokonezeka maganizo
- Rash
- Kuyabwa
- Fever
- Kuvuta kugona kapena kugona tulo
- Gasi
- Kutaya thupi
Kuwonjezera apo, mavuto aakulu a chiwindi, komanso matenda otchedwa lactic acidosis, amayamba kuchepa makamaka kwa odwala omwe amatenga tenofovir. Ngati mukumva zizindikiro zotsatirazi mutatenga tenofovir, muyenera kudana ndi dokotala wanu kapena kupeza chithandizo chamankhwala chodzidzimutsa:
- Kusunthira mosalekeza ndi / kapena kusanza
- Kupweteka m'mimba / m'mimba
- Zima
- Mtsinje wakuda
- Jaundice (kumaso kwa maso ndi / kapena khungu)
- Kutopa kwambiri
- Kupuma mofulumira kapena kovuta
- Kugona
- Kupweteka kwa minofu ndi / kapena kufooka
- Khungu lakuda
Amene sayenera kutenga Tenofovir
Aliyense amene ali ndi vuto la tenofovir sayenera kumwa mankhwalawa. Komanso, ndizofunika kudziwa momwe mulili kachilombo ka HIV chifukwa kutenga tenofovir kungakhale kovuta kwambiri kuchiza HIV. Ngati muli ndi kachilombo ka HIV ndi HBV, musayambe kuchiza matendawa popanda kufunsa dokotala yemwe amachiza matenda onsewa. Tenofovir amadziwika ngati mankhwala B gulu kuti agwiritsidwe ntchito pathupi, zomwe zikutanthauza kuti palibe umboni wosonyeza kuti ndi wovulaza kwa amayi omwe ali ndi pakati kapena mwana wake.
> Chitsime:
US Food and Drug Administration. Tizilombo toyambitsa matenda a Hepatitis.
Kupititsa patsogolo, Basow, DS (Ed), UpToDate, Waltham, MA, 2010.