Palibe Machiritso Komabe, Koma Zakudya za Kumadzulo Zikhoza Kusowa Triterpenes
Lupeol, yomwe imadziwikanso kuti fagarsterol, ndi malo achilengedwe omwe amapezeka m'mitengo ina ya m'nkhalango zam'mvula, komanso zakudya zina. Lupeol ndi ofunika kwambiri kwa asayansi omwe amaphunzira mankhwala omwe ali ndi mankhwala othandiza. Kafufuzidwe ndi kochepa kwa maphunziro a vitro ndi nyama, kotero ndikumayambiriro koyambako, koma Lupeol akuwoneka kuti ali ndi zotsutsana ndi zotupa komanso zotsutsana ndi khansa m'maphunziro ena.
Kodi Lupeol Ndi Chiyani?
Lupeol ndi ya gulu la mankhwala omwe amatchedwa triterpenes. Triterpenes ndizofunikira kwambiri pamagulu a maselo. Mavitaminiwa amachitanso chimodzimodzi ndi kolesterolini m'magulu a nyama-kutanthauza kuti, amathandiza kuti anthu osagwiritsira ntchito mankhwalawo azikhala osasuntha. Maphunziro a Triterpenes akhala akuphunziridwa ndi zochitika 25 zachipatala ndipo ali ndi chidwi chokhudzidwa ndi cholesterol .
Kumadzulo, tayerekezera kuti timadya pafupifupi 250 mg pa tsiku la triterpenes, makamaka kuchokera ku masamba, masamba, zipatso ndi ndiwo zamasamba. Kulowetsa kwapadera kungakhale kotchuka kwambiri m'mayiko a Mediterranean ndi anthu okhala ndi zakudya zomwe zimakhala ndi mafuta obiriwira.
Lupeol imatsutsana ndi ntchito ya biologic yokondweretsa kwambiri. Mafukufuku omwe amapereka chidziwitso chokhudza chilengedwe cha Lupeol amasonyeza kuti ndi wothandizira ambiri. Zikuoneka kuti maselo akuluakulu omwe amaphatikizapo kutupa ndi khansa akuphatikizidwa.
Kodi Zikuchokera ku Lupeol?
Zanthoxylum ndi mtundu wa mitundu yokwana 250 ya mitengo ndi zitsamba mumzinda wa citrus, womwe uli m'madera otentha ndi madera otentha padziko lonse lapansi. Mitundu ina imakhala ndi mtima wa chikasu, ndipo zipatso za mitundu yosiyanasiyana zimagwiritsidwa ntchito kupanga zonunkhira, tsabola wa Sichuan. Anthu amtunduwu amagwiritsidwanso ntchito ngati mitengo ya bonsai.
Makungwawa agwiritsidwa ntchito mu mankhwala ochiritsira kwa dzino la mano, colic, ndi rheumatism. Malo abwino a Lupeol mumtundu uwu ndi Zanthoxylum riedelianum, imodzi mwa mitengo yayitali kwambiri ku Amazon ya Peru. Chochititsa chidwi n'chakuti Lupeol imapezekanso ku zomera kuchokera ku Philippines, Ficus pseudopalma, yomwe yakhala ikugwiritsidwa ntchito monga mankhwala a mankhwala a impso ndi shuga. Mitengo yosiyana siyana tsopano imadziwika kuti ndi yabwino kwambiri ya Lupeol, ndipo Lupeol imapezekanso masamba monga kabichi, tsabola, nkhaka, phwetekere; ndi zipatso monga azitona, nkhuyu, mango, sitiroberi, ndi mphesa zofiira.
Kodi Mvula Yamkuntho Idzawathandiza Kuchiza Khansa ndi Kupewa?
Kafukufuku wasonyeza kuti zakudya zamtundu wa phytochemicals (zomwe Lupeol ndi imodzi yokha) zingachepetse kwambiri chiopsezo cha khansa zambiri zomwe zimafala pafupifupi 20 peresenti.
Kaya Lupeol idzapindulitsa pochiza khansa sichidzawonekere, koma kafukufuku wochokera ku vitro ndi zinyama zomwe zachitidwa mpaka pano zakhala zosangalatsa. Mwina cholimbikitsanso ndi chakuti Lupeol, pogwiritsa ntchito mankhwala ochiritsira, amaoneka kuti sakuwonetsa poizoni ndi maselo omwe amaphunzira. Izi zati, chitetezo ndi poizoni sizinayesedwe mu mayesero a anthu, ndipo zotsatira zingakhale zosiyana ndi maphunziro a mu vitro ndi nyama.
Pulogalamu pa Sukulu ya Mankhwala ndi Zaumoyo Zapamtima, University of Wisconsin-Madison wakhala akuyesa zotsatira zopindulitsa za Lupeol kwa mitundu yosiyanasiyana ya khansa monga prostate, khungu, khansa ya pancreatic ndi khansa. Malingana ndi kafukufuku wokhudzana ndi mankhwala a khansa kuchokera ku mizere yambiri ya selo, gulu ili limakhulupirira kuti Lupeol amatha kugwira ntchito pamagulu angapo a maselo.
Nanga Bwanji Za Khansa za Magazi?
Maphunziro ndi Lupeol ndi oyambirira, ndipo kufufuza kwina kuli kofunika kuti tithe kuunika pa funso ili. Padakali pano, kafukufuku wochokera m'mabuku angapo apitawo akulonjeza kuti akupitiriza ntchito.
Kafukufuku wopangidwa ndi Aratanechemuge ndi anzake akuwonetsa kuti Lupeol imapangitsa apoptosis (programmed cell cell death) ya maselo a human promyelocytic HL-60 maselo a m'magazi.
Kafukufukuyu anawonetsa kuti Lupeol imapangitsa kusintha kwa DNA ndi kugawikana kwa DNA (zomwe zimagwiritsidwa ntchito pongopeka) m'njira yomwe imadalira mlingo wa Lupeol.
Gulu lina la ochita kafukufuku, Cmoch ndi anzake, linasonyeza kuti Lupeol imapangitsa selo kufa m'magawo osiyanasiyana a khansa, kuphatikizapo T-lymphoblastic leukemia, ndi multipleeloma yambiri.
> Zotsatira:
> Moreau RA, Whitaker BD, Hicks KB. Phytosterols, Phytostanols, ndi Conjugates Zawo mu Zakudya: Zokonzeka Zachilengedwe, Zowonongeka Zomwe Zimagwiritsidwa Ntchito, ndi Kugwiritsa Ntchito Zolimbikitsa zaumoyo. Prog Lipid Res. 2002; 41: 457-500.
Santiago LA, Meya ABR. Lupeol: Triterpene ya Antioxidant ku Ficus Pseudopalma Blanco (Moraceae). Asia Pac J Kutentha Kwambiri. 2014; 4 (2): 109-118.
> Saleem M. Lupeol, Mankhwala Oletsa Kuletsa Kutentha ndi Matenda a Kanseri Triterpene. Khansa Lolani . 2009; 285 (2): 109-115.