Mphapiritsi Mipira Yopereka Magazi Amagazi ndi Zotsatira Zotsatira

Zowonjezereka tsopano kuti anthu amapereka maselo amkati a magazi ammimba (PBSCs) kuti awapatse, ngakhale kuti nthawi zina anthu akupatsabe mafupa. Ngati mukuganiza zopereka mafupa m'malo mwa PBSCs onani zoopsa zomwe mungapereke pogwiritsa ntchito fupa la fupa .

Mwazi Wopanda Mitsempha ya Mitsempha ya Magazi

Kuti mumvetse mavuto omwe mungapereke opereka maselo ofooka, angathandize poyamba kuti ayang'ane momwe maselo amathandizira amasonkhanitsira.

Kuyambira masiku 4 kapena 5 musanayambe njirayi mumapatsidwa jekeseni kuti muwonjezere chiwerengero cha maselo a tsinde m'magazi anu. Ndondomeko yokha imayambira kudzera muyiyi yaikayi mdzanja lanu kapena mzere wapakati mu chotengera chachikulu cha magazi. Magazi anu amasonkhanitsidwa, osankhidwa kuti achotse maselo ofooka, apita mmbuyo mu thupi lanu.

Zowopsa

Pali zochepa zoopsya zomwe mungaganizire muzipangizo zapadera za magazi.

Choyamba chimakhudzana ndi mankhwala omwe mumalandira m'masiku omwe musanayambe. Mankhwala otchedwa granulocyte colony factor (Neupogen) amaperekedwa tsiku ndi tsiku kwa masiku 4 kapena asanu mwa jekeseni, kuti muwonjezere kuchuluka kwa maselo a tsinde omwe alipo m'magazi anu. Zotsatira za mankhwalawa nthawi zambiri zimaphatikizapo kupweteka kwa mafupa, komanso chiopsezo chotengera. Panthawi ina ankaganiza kuti chotupa cha granulocyte chikhoza kuonjezera chiopsezo cha khansa ya m'magazi mwa iwo omwe adachilandira, koma izi sizikuwoneka choncho, ndipo mu phunziro limodzi lalikulu chiwerengero cha khansa ya m'magazi mwa anthu omwe analandira granulocyte chochititsa chidwi mu Kukonzekera kwa maselo osungira operekera kwenikweni kunali kochepa kwambiri kusiyana ndi anthu ambiri.

Njira yachiwiri yomwe ingakhale yoopsa ndi yokhudza magazi. Nthawi zina kuti muikepo IV, mzere wapakati uyenera kuikidwa mu mitsempha yambiri mu thupi lanu. Izi zimayambitsa kuika magazi komanso chiopsezo chosavuta cha kupopera mapapo anu. Popeza magazi anu (osachepera maselo amtundu) amabwezeretsedwa m'thupi lanu, simudzakhala ndi zizindikiro zambiri zomwe anthu amazisonyeza ndi magazi opereka.

Pamene magazi anu akusankhidwa (ndondomeko yotchedwa apheresis) mukhoza kumverera pang'ono. Mwinanso mungakhale ndi zowawa, zokhala m'manja mwanu, ndikumva zowawa pamilomo yanu. Izi ndizokhalitsa ndipo sizingatheke kwa nthawi yaitali kusiyana ndi maola angapo mutatha kusonkhanitsa.

Zoopsa Zochepa ndi Zotsatira Zachimake

Zotsatira zowonongeka kwambiri za zopereka zapakati pafupipafupi zimakhalapo masiku ambuyomu asanaperekedwe ndipo zimakhudzana ndi zotsatira za jekeseni ya granulocyte. Izi zimaphatikizapo kupweteka kwa mafupa ndi thupi.

Zingakhale zosasangalatsa ndi kuika ma IV, kuphatikizapo zipsera ndi manja ngati momwe taonera pamwambapa.

Zoopsya Zowopsya ndi Zotsatira Zotsatira

Zochitika zazikulu zovuta ndizochepa kwambiri ndi zopereka zapakati. Poyamikira zopereka za ndondomeko ya National Donor Grant, osachepera 1% a operewera adakumana ndi vuto lalikulu.

Padziko lonse lapansi, kafukufuku wina adawoneka pa anthu opitirira 23,000 omwe adapereka maselo amkati a magazi. Pakati pa anthuwa, panali 4 kupha komanso zochitika zovuta kwambiri (makamaka zokhudzana ndi mtima), koma phunzirolo linaphatikizapo mapulogalamu kuzungulira dziko lapansi ndi zofunikira zofunikira kwambiri kwa opereka omwe ali ku United States.

Opereka ndi Odwala

Ngati mukuganiza zopereka maselo othandizira munthu wina kunja kwa banja lanu, mukhoza kudabwa ngati mutha kukhala ndi mwayi wolankhula ndi wolandira maselo anu. Pali njira zokhudzana ndi chinsinsi pankhaniyi, koma zingakhale zosangalatsa kuwerenga nkhani za opereka ndi odwala omwe ali ndi mwayi wokumana nawo.

Kusankha Zanu

Kwenikweni, kupereka kwa magazi pamagazi kumayambira maselo ndi njira yotetezeka kwambiri, yokhala ndi moyo wopulumutsa moyo. Ngati mukuganiza zopereka, pewani nthawi yoyezetsa zoopsa ndi zopindulitsa, ndipo sankhani zomwe zingakuchitireni zabwino.

_Zotsatira:

_{American Society of Clinical Oncology. Cancer.Net. Kupereka Bone Marrow.}

_{Halter, J., Kodera, Y., Ispizua, A. et al. Zochitika zoopsa kwa opereka chithandizo pambuyo pa zopereka zapakati za maselo a hematopoietic. Haematologica . 2009. 94 (1): 94-101.}

_{Miller, J., Perry, E., Price, T. et al. Mapulogalamu obwereza ndi otetezeka a mmala ndi operekera PBSC: zomwe zinachitikira Pulogalamu ya Ndalama Yothandizira Ndalama ya National Marrow. Biology ya Bone Marrow Kukula . 2008. 14 (Suppl 9): 29-36.}

_{National Bone Marrow Programme Othandizira. Kupereka Bone Marrow.}