Sally anali ndi zovuta ndi kudya. Nthaŵi zambiri ankaona kuti chakudya chikugwedezeka pamene akudya, zomwe zimamupangitsa kuti asakhale wosasangalala. Adam wazaka zinayi anali kukula bwino, nthawi zambiri ankakhumudwa patebulo la chakudya, ndipo nthawi zambiri ankakana kudya. Zili choncho kuti onse awiri Sally ndi Adam anali ndi chikhalidwe chimodzimodzi: Eosinophilic esophagitis (EoE).
Kodi Eosinophilic Esophagitis (EoE) Ndi Chiyani?
Eosinophilic esophagitis ndi gawo la zakudya zowonjezera, zomwe zimayambitsa matenda.
EoE ndi matenda aakulu a chitetezo cha mthupi, omwe amangodziwika ndi madokotala. Chiwerengero cha matendawa chawonjezeka pazaka 10 zapitazo, zofanana ndi kuchuluka kwa chiwerengero cha matenda odwala matenda a chifuwa chachikulu ndi matenda a mphumu.
Maosinophil ndi maselo oyera a m'magazi omwe amapezeka m'thupi lanu, koma mu EOE amamanga m'mimba (chubu yomwe imagwirizanitsa mmimba ndi m'mimba; Mankhwalawa amatulutsa mapuloteni, omwe amachititsa kutupa kapena kutupa. Izi zingayambitse kupweteka komanso kuchepa kwa nthawi ndi kupanga mapepala a fibrous m'kati mwa chigawo chanu.
Mankhwalawa amamanga m'mimba chifukwa thupi limagwira chakudya chokwanira, zakudya zina monga mungu, kapena zimagwirizana ndi asidi reflux. Pafupifupi 50 peresenti ya anthu omwe ali ndi EoE amakhalanso ndi zowawa za nyengo kapena mphumu. Kuwonongeka kwa mimba kumapangitsa kuti kukhale kovuta kuvomereza kapena kungachititse kuti kumverera kwa chakudya kukhale kolimba.
Zizindikiro
Ana ndi akuluakulu angathe kupeza zizindikiro zosiyana ndi EoE.
Akuluakulu akhoza kukhala ndi zizindikiro zosiyanasiyana, monga :
- Kuvuta kukumeza, kumatchedwanso dysphagia
- Kupatsa chakudya (chakudya chimalowa pambuyo pakumeza)
- Matumbo a chifuwa ndi ofanana ndi kukwatulidwa, komwe sikungathetsere ndi antacids
- Kupweteka kwa m'mimba kwambiri
- Zizindikiro zomwe sizikugwirizana ndi mankhwala a reflux (GERD) a gastroesophageal (GERD)
- Kubwezeretsa (kubwerera kumbuyo kwa chakudya chosagwiritsidwa ntchito)
Zizindikiro za ana zingaphatikizepo zotsatirazi:
- Kukhumudwa
- Mavuto ndi kudyetsa
- Kuthamanga
- Kupweteka m'mimba
- Mavuto akumeza
- Kuwona chakudya kumakhala
- Kulemera kolemera ndi kukula (mwachitsanzo, kulephera kukula, kuperewera kwa zakudya m'thupi, kusowa kwa zakudya)
- Osagonjera mankhwala a GERD
Zowopsa
Pali zifukwa zingapo zomwe zimapangitsa kuti EoE ikhale yowonjezereka, koma umboni wokhudzana ndi momwe zidzakhalira, komanso ngati EoE zidzachitikabe. Komabe, pali zifukwa zochepa zoopsya zomwe zadziwika:
- Gender : EoE ndi yofala kwambiri kuposa amuna.
- Genetics : EoE ikuwoneka ngati yokhudzana ndi chibadwa; ngati wachibale ali ndi EoE, chiopsezo chili chokwanira kuti apange EoE.
- Matenda a mphumu ndi mphumu : Anthu omwe ali ndi chifuwa cha zakudya, matenda ena, ndi mphumu ali pachiopsezo chachikulu chokhazikitsa EoE.
- Kumene mukukhala : Kukhala mu nyengo yozizira kapena youma kumawonjezera chiopsezo chanu kwa EOE.
- Nyengo ya chaka : Anthu ambiri amapezeka pakati pa kasupe ndi kugwa pamene zowonongeka ndi zachilengedwe ndipo anthu amakhala kunja.
Kudziwa
Mayesero angapo amachitikira kuti adziwe EoE komanso kuphatikizapo kumapeto kwa mapepala osasintha.
Mapulogalamu apamwamba kwambiri amatha kugwiritsa ntchito chubu yayitali yayitali ndi kamera pamapeto kumalowa pakamwa ndi pansi. Njirayi imalola dokotala kuti ayang'ane mayendedwe anu ndikuyang'ana kutupa ndi kutupa, kapena zovuta zina zogwirizana ndi EoE. Chiwopsezo chimaphatikizapo kutenga nyemba za minofu yanu m'madera angapo (nthawi zambiri awiri mpaka anayi).
Ngati mukuganiza kuti muli ndi EOE, dokotala wanu akhoza kuchita mayeso ena monga kuyezetsa magazi, mayesero a mankhwala, mayeso a zakudya, komanso kusintha kwa zakudya.
Chithandizo
Ngati mwapezeka ndi EoE, mudzafunika chithandizo chamankhwala nthawi zonse monga EoE ndi matenda aakulu, obwereranso.
Zotsatirazi ndizo njira zowonongeka kwambiri; Zitha kugwiritsidwa ntchito pothandizira ndondomeko yothandizira kwambiri:
Zakudya
Pali 10-15 zakudya zomwe zimadetsa EoE, koma thupi limatha kuchita chakudya chilichonse. Zakudya za Trigger ziyenera kuchotsedwa pa zakudya nthawi yaitali kuti zizindikiro zikhazikitsidwe. Kukhumudwa kwa EOE ndikuti thupi lanu likhoza kukhala likuchita ndi chakudya chomwe mumadya tsiku ndi tsiku-chimene sichikuwoneka kuti n'chovuta kwa inu. Zina mwa zakudya zofala zomwe zimayambitsa EoE ndi mkaka , tirigu , dzira ndi soya .
Ngati chakudya kapena chakudya choposa chimodzi chimachititsa zizindikiro zanu, zakudya zimenezo zidzachotsedwa pa zakudya zanu. Matenda ena a EoE amafunika kusintha kwakukulu kwa zakudya. Chakudya chochotseratu chingakhale mbali ya dongosolo la mankhwala. Nthawi zina, mayendedwe apadera omwe amatchedwa zakudya zapachiyambi zimagwiritsidwa ntchito kuthetseratu zakudya zonse za mapuloteni pamene akuphimba zakudya za munthu, makamaka ngati zakudya zambiri ziyenera kuchotsedwa pa zakudya.
Mankhwala
Mankhwala angapo angagwiritsidwe ntchito pochiza EoE. Kawirikawiri, ayimayi imayesedwa poyamba, koma anthu ena sangasonyeze kuti akukula bwino. Mankhwala otchedwa steroid operekedwa ngati thukuta kapena osakanikirana ndi slurry angagwiritsidwe ntchito. Izi zingathandize kuthetsa kutupa kwa anthu ena popanda zotsatira zogwiritsidwa ntchito ndi steroids chifukwa sichilowetsedwa m'magazi. Ngati mankhwalawa sakugwira ntchito, steroids, monga prednisone, iyenera kulamulidwa. Steroids ikhoza kuchepetsa kumanga kwa eosinophils ndikulola khosi lanu kuchiritsa. Anthu ena akhoza kukhala pa steroid nthawi zonse.
Kusintha
Kwa iwo omwe amawonongeka kwambiri (otchedwa strictures), njira yotchedwa dilation ingakonzedwe. Ndondomekoyi imatambasula mitsempha ndipo imapangitsa kumeza kumakhala kophweka. Komabe, pali zoopsa zowonongeka ndi kuperewera. Kusinthasintha sikukutanthauza kutupa kwina.
> Zothandizira:
> Furuta et al. Kusagwirizana kwa Eosinophilic Eopinitis kwa Ana ndi Akuluakulu: Kukonzekera Mwadongosolo ndi Kukambirana Zomwe Zilipo pa Kuzindikira ndi Kuchiza. Gastroenterology. 2007. 133: 1342-1363.
> Liacouras CA. Zosokoneza maopaleshoni: Kusinthidwa kwavomerezedwa kwa ana ndi akulu. The Journal of Allergy and Clinical Immunology. 2011; 128: 3-20.
> American Academy of Erazer, Asthma, ndi Immunology: http://www.aaaai.org/conditions-and-treatments/related-conditions/eosinophilic-esophagitis.aspx