Kodi IPF ndi Chiyani Zimayambitsa Izo?
Ngati inu kapena wokondedwa wanu mwapezeka kuti muli ndi idiopathic pulmonary fibrosis (IPF), dziwani kuti anthu ochepa chabe amadziwa matendawa. Ngati mutayamba kufufuza zambiri pa IPF, simungapeze zambiri zabwino. Mpaka mu 2014 panalibe mankhwala omwe alipo omwe amachititsa kusiyana kwakukulu kwa anthu omwe ali ndi matendawa. Zikondwerero, izo zikusintha-tsopano pali CHIFUKWA cha matenda omwe akukweza miyoyo.
Kodi Idiopathic Pulmonary Fibrosis (IPF) ndi chiyani?
IPF ndiyo mtundu wambiri wa matenda omwe amadziwika kuti idiopathic interstitial pneumonia. Mawu akuti interstitial amatanthauza kuti mkhalidwe ulipo m'mapapu pakati pa alveoli ( timagulu ting'onoting'ono ta mpweya kumapeto kwa mtengo wopuma mpweya umene mumapanga mpweya wabwino ndi carbon dioxide) komanso m'zinthu zowonongeka. Fibrosis amatanthauza scarring. Izi zimakhala zovuta kwambiri m'makoma ozungulira ndipo zimakhala zovuta pakati pa iwo zomwe zimalepheretsa mpweya kuti upite mumakoma a alveoli ndi m'magazi.
M'mbuyomu, ankaganiza kuti IPF inali yotupa. Tsopano zikuganiziridwa kuti zimayamba ndi kuwonongeka kwa mapapo kuchokera ku magwero omwe amachokera, pambuyo pake ndi machiritso osachiritsika-fibrosis.
Kuti mudziwe mmene izi zilili, ganizirani khungu lanu limene limachiritsa ndi chilonda. Mu anthu ambiri, kudula kumachiza ndi mzere wabwino wofiira womwe umatembenuka woyera ndi nthawi.
Kwa anthu ena, khungu limachiritsa mwachilendo, kusiya khungu lakuda ndi losaoneka bwino. The fibrosis mu IPF ndi ofanana ndi mtundu uwu wa scarring, koma wosawoneka kunja kwa thupi.
Kuwonjezera pa kukhala matenda okhaokha, khumi mwa anthu omwe ali ndi IPF akuyembekezera kukhala ndi khansa ya m'mapapo.
Kodi IPF Ndi Yotani Kwambiri?
Mawerengero amasiyana poyang'ana zochitika za idiopathic pulmonary fibrosis, koma kuvomereza ndikuti vuto silikudziwika; anthu ambiri amakhala ndi IPF ndipo amapezeka kuti ali ndi vuto linalake, kapena amadutsa asanayambe kupeza matenda oyenerera.
Malinga ndi kafukufuku umodzi ku United States, anapeza kuti chiwerengero (chiwerengero cha anthu omwe amapezeka chaka chilichonse) cha IPF chinali 58.7 pa 100,000 anthu. Mufukufuku wina wa 2011, anapeza kuti kuchulukitsa (chiwerengero cha anthu omwe ali ndi matenda) a IPF chinali milandu 495.5 pa 100,000 omwe amapatsidwa thandizo la Medicare. (Matenda omwe sali ochepa omwe amatanthauza kuti ocheperapo 1 pa 50,000 ali nawo Choncho, IPF ndi yachilendo, koma sizodziwika.)
Kuyang'ana anthu akufa kuchokera ku makadi a IPF ananeneratu kuti anthu 13,000 mpaka 17,000 adzafa ndi IPF ku United States mu 2014 ndipo pakati pa 28,000 ndi 65,000 anthu adzafera ku Ulaya. Pofotokoza izi, pafupifupi 40,000 anthu amafa ndi khansa ya m'mawere chaka chilichonse ku United States, kupanga IPF kukhala chifukwa chachikulu cha matenda ndi imfa.
Ndani Amalandira IPF? Zifukwa ndi Zoopsa
Sindikudziwika chomwe kwenikweni chimayambitsa IPF, motero, mawu akuti "idiopathic," omwe amatanthauza "sitikudziwa chifukwa." Izi zati, pali zifukwa zomwe zingayambitse anthu ku matendawa.
Ena mwa awa ndi awa:
- Zaka - IPF nthawi zambiri imapezeka m'zaka zapakati ndi zapakati.
- Kusuta - Pafupifupi 60 peresenti ya anthu amene amapanga IPF ali ndi mbiri ya kusuta.
- Matenda opatsirana monga kachilombo ka Epstein-Barr , komwe kumayambitsa matenda opatsirana a mononucleosis.
- Kuwonetsa zachilengedwe ndi ntchito.
- Matenda a reflux a Gastroesophageal (GERD) - Ambiri mwa anthu omwe ali ndi IPF ali ndi mbiri ya GERD ndi kupweteka kwa mtima.
- Mbiri ya banja (zowonongeka kwa majini ) - IPF imayendetsa m'mabanja ndipo zochepa za kusintha kwa majini zimawoneka kuti zikuwonjezera chiopsezo.
Pali zifukwa zambiri zomwe zimayambitsa pulmonary fibrosis, monga ma radiation ndi mankhwala, koma izi mwakutanthauzira sizingagwirizane ndi mankhwala omwe amachititsa kuti thupi liziyenda bwino.
Mawu Ochokera
Pazifukwa zosadziwika, anthu akufa kuchokera ku IPF akuwoneka akuwonjezeka padziko lonse lapansi. Pa nthawi imodzimodziyo, mankhwala atsopano ndi othandizira akupangidwa ngati kufufuza kwa matendawa kukupitirirabe . Pambuyo poyezetsa matenda , dokotala wanu ayenera kugwirira ntchito limodzi kuti apeze chithandizo chamankhwala chomwe chimagwirira ntchito payekha. Pali mankhwala osiyanasiyana omwe alipo, ndipo odwala ena akhoza kukhala opaleshoni yokweza. Kuonjezerapo, magulu othandizira alipo pomwe mungathe kugwirizana ndi ena ndikuphunzira njira zothandizira kukhala moyo wabwino ngakhale kuti muli ndi IPF. Potsirizira pake, gawo lanu lotetezeka mu chisamaliro chanu cha thanzi lingapangitse kusiyana, naponso.
> Zotsatira:
Antoniou, K., Tomassetti, S., Tsitoura, E., ndi C. Vancheri. Khansara ya Idiopathic pulmonary fibrosis ndi mapapo: kachipatala ndi ma pathogenesis. Malingaliro enieni mu Pulmonary Medicine . 2015 Sep 18. (Epub patsogolo pa kusindikiza).
Ghebremariam, Y. et al. Pulototopic zotsatira za proton pump inhibitor esomeprazole zomwe zimayambitsa kupweteka kwa mapapo ndi fibrosis. Journal of Translational Medicine . 2015. 13: 249.
Hutchinson, J., McKeever, T., Fogarty, A., Navaratnam, V., ndi R. Hubbard. Kuchuluka kwa chiwerengero cha anthu padziko lonse kuchokera ku idiopathic pulmonary fibrois m'zaka za m'ma 2500. Annals wa American Thoracic Society . 2014. 11 (8): 1176-85.
Idiopathic Pulmonary Fibrosis Research Center Network, Martinez, F., deAndrade, J., Anstrom, K., King, T., ndi G. Raghu. Mayeso a randomzedwe a acetylcysteine mu idiopathic pulmonary fibrosis. New England Journal of Medicine . 2014. 370 (22): 2093-101.
Spagnolo, P., Maher, T., ndi L. Richeldi. Idiopathic pulmonary fibrosis: Zotsatira zamakono za mankhwala opatsirana mankhwala. Pharmacology & Therapeutics . 2015. 152: 18-27.