Mankhwala Ena Angayambitse Matenda M'mimba
Kwa anthu ena, mankhwala enaake kapena mankhwala owonjezera amatha kupweteka m'mimba, kupweteka, kapena kukwiya. Kwa anthu omwe ali ndi matenda opatsirana kwambiri (IBD) , kupeŵa mankhwala omwe angabweretse mavuto m'mimba ndi ofunikira, makamaka ngati kale pali mbiri ya mankhwala omwe amachititsa kuti azivutika kwambiri m'mimba. Ngakhale mavuto am'mimba nthawi zina amachititsa zizindikiro, zimatha kukhalapo koma sizimayambitsa zizindikiro zilizonse.
Ena mwa mankhwala omwe amadziwika kuti amachititsa vuto la m'mimba ndi mankhwala osagwiritsa ntchito steroidal anti-inflammatory (NSAIDs), antacids, anticholinergics, ndi antchito a H2 omwe amalandira mankhwala.
NSAIDs
Mwina chifukwa chakuti nthawi zambiri amagwiritsidwa ntchito pa ululu wa tsiku ndi tsiku ndipo angagulidwe pa-counter-a-counter, NSAID ndi mankhwala omwe nthawi zambiri amachititsa kukwiya m'mimba. Chifukwa chake NSAID zimakhudza chida cha mmimba, mucosa. NSAID zimayesetsa kuchepetsa kupweteka ndi kutupa chifukwa zimathandiza kuti pakhale njira zomwe zimapangitsa kuti pakhale mankhwala omwe amatchedwa prostaglandins . Prostaglandins amagwira ntchito yotupa, motero popanda kupweteka, kupweteka ndi kutupa kumachepetsedwa. Komabe, iwonso ndi ofunika kuntchito ina yofunikira yomwe imachitika mmimba: kulenga ndi kusunga mkatikati mwa mimba, yomwe imatchedwa mucosa.
Msosa uli ndi maselo omwe amachititsa ntchentche , chovala choyera chachikasu chomwe chimaphika mmimba ndikuchiziteteza kuchokera ku juzi zopweteka kwambiri.
NSAID zimasokoneza kupanga ntchentche, zomwe zimayambitsa zofooka mu mucosa wosanjikiza. Kuchepetsanso mchere kumapangitsa kuti thupi likhale lopweteka kwambiri. Pamene pali kutupa m'mimba, imatchedwa gastritis . Pamene kutupa kumapitirira kungachititse kuti magazi awonongeke, zilonda (zilonda m'mimba mwake), kapena kawirikawiri, perforation (dzenje mmimba).
Anthu ena ali pachiopsezo chakumva kuwawa kwa m'mimba mutatha kutenga NSAID, ndipo izi zikuphatikizapo okalamba kapena omwe ali kale ndi vuto la m'mimba. Anthu achikulire omwe amatenga NSAID nthawi zonse kuti amve kupweteka ndi kutupa kwa nyamakazi kapena zochitika zina ali pangozi ya kukwiya m'mimba. Mbiri yakale ya zilonda zam'mimba kapena gastritis imayambanso ndi chiopsezo chachikulu cha mavuto pambuyo mutatenga NSAIDs. Nthawi zina, amatha kupatsidwa mankhwala omwe angathandize kuteteza mimba m'mimba chifukwa cha zotsatira za NSAID.
Zizindikiro za mkwiyo wa m'mimba kuchokera ku NSAID zingaphatikizepo izi:
- Magazi mu mpando
- Magazi mu masanzi
- Kutentha kumverera mmimba kapena mmbuyo
- Kutsekula m'mimba
- Kutsekemera (kudzikuza)
- Ululu m'mimba
- Malo otayika kapena wakuda
Malangizo othandizira kupewa kutaya mimba kuchotsa NSAID ndi:
- Osamamwa mowa panthawi yomwe akutenga NSAID
- Kumamatira kuyezo umene mwauzidwa komanso osapereka zochuluka kuposa momwe mukufunira
- Tengani NSAID pamodzi ndi chakudya, mkaka, kapena madzi
- Tengani NSAID patapita nthawi (onani ndi dokotala poyamba)
- Tenga mapiritsi a NSAID (ayang'ane ndi dokotala poyamba)
Kuchotsa Mimba Yamatenda
Mitundu ingapo ya mankhwala ingayambitse kuchepetsa kupweteka kwa m'mimba. Kuchepetsa kuchepa kwa mimba kumatanthawuza kuti minofu m'mimba yomwe imayambitsa kuchotsa imachepetsedwa, ndipo chakudya sichichotsedwa mmimba pamlingo womwe chiyenera kutero.
Kwa anthu amene amapezeka ndi gastroparesis , omwe ndi matenda omwe amachititsa kuti m'mimba kuchedwetsa kutaya, mankhwala omwe amachititsa kuti vutoli lizichepetse zingabweretse mavuto aakulu.
Mitundu ina ya mankhwala omwe angayambitse kuchepetsa chakudya kuchokera m'mimba ndi awa:
- Aluminium hydroxide. Mavitamini ena ali ndi aluminium hydroxide monga imodzi mwazikulu zogwirira ntchito. Antacids amagwira ntchito kwa kanthaŵi kochepa, mphindi 30 mpaka 60, ndipo pali mphamvu yowonjezera pakutha, itayambika m'mimba mwake. Mankhwala omwe ali ndi mankhwalawa angathenso kumadzetsa kuvomereza pamene agwiritsidwa ntchito nthawi yayitali.
- Mankhwala oletsa anticholinergic. Mankhwalawa amagwiritsidwa ntchito pochiza matenda, kuvutika maganizo, ndi kusadziletsa. Zina mwa mankhwalawa ndi Benadryl (diphenhydramine) , tricyclic antidepressants, barbiturates, relax relaxation, ndi benzodiazepines.
- Otsutsana ndi H2 . Mankhwala ena mwa mankhwalawa, omwe amagwiritsidwa ntchito pochiza matenda a reflux (GERD) , amatha kuchepetsa chakudya kuchokera m'mimba. Komabe, ena omwe amatsutsana ndi H2 akhoza kukhala ndi zotsatira zosiyana ndizo ndipo amachulukitsa mlingo umene chakudya chimachotsedwa m'mimba. Zotsatira zenizeni za mankhwala omwe ali m'kalasiyi adakali akuphunzira.
Chidziwitso Chochokera
Pangakhale ngozi ndi mankhwala aliwonse, ngakhale omwe alipo pa-counter-counter. Ichi ndi chifukwa chake n'kofunika kuti dokotala adziwe mankhwala onse omwe amagwiritsidwa ntchito, ngakhale omwe timaganizira kuti ndi owopsa, kapena kuti timaiwala chifukwa timagula nawo mankhwala osokoneza bongo ndikuwatenga nthawi zambiri. Kwa anthu ambiri, NSAIDs ndi mankhwala osokoneza bongo sizingayambitse mavuto akuluakulu, koma mavuto a m'mimba akamakula, ngati mankhwalawa amagwiritsidwa ntchito nthawi zonse, zikhoza kukhala chitsimikizo pa zomwe zingayambitse zizindikiro .
> Zotsatira:
> American College of Gastroenterology. "Gastroparesis." Phunziro la Odwala ndi Zothandizira. 2015.
> Wallace JL. "Njira, kuteteza komanso kuchipatala zimatanthawuza kuti mankhwala osokoneza bongo amachititsa kuti anthu asamagwiritse ntchito mankhwala osokoneza bongo." World J Gastroenterol . 2013 March 28; 19: 1861-1876. do: 10.3748 / wjg.v19.i12.1861