Mankhwalawa amathandiza kuti thupi likhale lofewa
Ceramide ndi mamolekyu amtundu wa khungu amene amalepheretsa kuteteza thupi ndi kusunga khungu.
Kumene kuli Ceramides
Khungu lapamwamba la khungu limatchedwa epidermis , ndipo chapamwamba pamwamba pa epidermis amatchedwa stratum corneum (SC). Ngakhale kuti SC ndi yoonda kwambiri-10-30 millimeters kapena limodzi la magawo khumi la pepala-ndilo vuto lalikulu la khungu.
Zimasunga mankhwala omwe amayamba kukhudzana ndi khungu kuchoka mu thupi, ndipo amateteza madzi mkati mwa khungu kuti asatulukemo.
SC ili ndi mitundu itatu ya lipids: ceramides, cholesterol, ndi mafuta omvera acids. Lipids iyi ili ndi mapangidwe osiyanasiyana a mankhwala komanso ntchito zosiyanasiyana m'thupi lonse. Pali mitundu 9 ya ceramide mu SC, yomwe imatchedwa ceramide 1 kupyolera mu ceramide 9, ndipo amawerengera 40 peresenti mpaka 50 peresenti ya lipids kumtundu wapamwamba.
Mmene Ceramides Amathandizira Ena Matenda a Khungu
Asayansi aphunzira kuti anthu omwe ali ndi eczema ali ndi keramizi ochepa mu SC yawo. Komabe, anthu omwe ali ndi psoriasis (kuthamanga kwachabechabe, komwe kumasokonezeka nthawi zina ndi chizungu) ali ndi chiwerengero chofanana cha ceramides monga anthu omwe ali ndi khungu lenileni. Komabe, anthu omwe ali ndi psoriasis alibe ceramide 1, 3, 4, ndi subset ya 5 ndi 6, ndipo ali ndi ceramide 2 ndi gawo lina lachisanu.
Kusintha Cereamide Kungapangitse Mtengo wa Eczema
Kafukufuku wam'mbuyo awonetsa kuti lipids ikhoza kusinthidwa ndi zokonzekera zamatsenga. N'zochititsa chidwi kuti mitundu yonse itatu ya lipids iyenera kusinthidwa pa chiŵerengero china kuti izibwezeretsanso khungu. Ngati kusalakwitsa kwa lipids kumagwiritsidwa ntchito, zimatenga nthawi yaitali kuti khungu lichiritse.
Mphamvu ya machiritso ya ceramides pa eczema yakhala ikuphunziridwa, koma palibe maphunziro omwe adayang'aniranso momwe machiritso angapangire psoriasis.
Ubale pakati pa Ceramides ndi ukalamba
Mukamaliza zaka 30 zapitazi, chiwerengero cha ceramides khungu lanu chimayamba kuchepa. Chotsatira chake, chotchinga cha khungu lanu chimachepa, ndipo izi zingayambitse zizindikiro zina za khungu, monga kukhumudwa, kuuma, ndi kufiira. Zina mwazinthu zomwe zili ndi ceramides zingathandize kusintha zizindikirozi, komanso kuchepetsa zizindikiro za ukalamba pakhungu, ngati makwinya.
Zosakaniza zokhala ndi ma Ceramide Si Zonse
Pali zinyontho zowonjezera zomwe zimati zili ndi ceramide monga zowonjezera, koma izi ndizokhazikika pokhapokha ngati zitha kusonyeza kuti:
- Mankhwalawa amakhalanso ndi cholesterol komanso mafuta owonjezera
- Chiŵerengero cha zinthu zitatu izi ndi zolondola
Pewani Zakudya Zovomerezeka Ndi Zodzoladzola
Palibenso kafukufuku wokwanira pakadali pano kutsimikizira kuti mankhwala opatsirana ndi ceramides angathandize kuthandizira khungu, choncho ndi bwino kumamatirana ndi timadzi timeneti timene timapuma.