Nthaŵi zina Plasmapheresis imagwiritsidwa ntchito monga mankhwala m'magulu angapo a ubongo kuphatikizapo MS, makamaka panthawi yovuta kwambiri yomwe sichimvera corticosteroids . Ndizopweteka kwambiri, ndipo zotsatira zake sizodziwika.
Kodi Plasmapheresis N'chiyani?
Plasmapheresis, yomwe imatchedwanso kuti mankhwala opangidwa ndi plasma , ndiyo njira imene makina kunja kwa thupi la munthu amachotsa magazi mwa munthuyo ndiyeno amalekanitsa gawo la plasma la magazi - plasma kukhala madzi kapena gawo la magazi.
Kenaka plasma imatayidwa ndi kusandulika ndi mtundu wambiri wamadzimadzi, nthawi zambiri amapereka plasma kapena solutionin albumin, asanabwezere kubwerera kwa munthuyo.
Kodi Cholinga cha Plasmapheresis N'chiyani?
Cholinga cha plasmapheresis ndicho kuchotsa zinthu zoipa kapena "zoipa" m'magazi. Pankhani ya MS, izi zingathe kukhala ndi zida zolimbana ndi chitetezo cha m'thupi zomwe zimayambitsa machitidwe apakati.
Njira
Pa plasmapheresis, singano zidzaikidwa mmanja mwanu, kapena nthawi zina kumalo ena, ngati khosi, ngati mitsempha mu mkono sungapezeke. Mwazi udzatulutsidwa kuchokera mthupi mwako kupyolera mu singano m'dzanja limodzi. Anticoagulant (kawirikawiri citrate) imaphatikizidwira ku magazi kuti asatayike. Magazi anu amatha kupyolera mu chubu kupita mu "selo losiyanitsa magazi." Kusiyana kwa maselo a magazi ndi centrifuge yomwe imasiyanitsa plasma kuchokera kumbali zina za magazi anu, omwe ali ziwalo zapakati (zomwe zimapangidwa ndi maselo ofiira a magazi, maselo oyera, ndi mapulogalamu).
Zipangizo zamagulu zimagwirizananso ndi plasma wopereka ndalama m'malo mwake ndikubweranso kwa iwe pogwiritsa ntchito singano. Nthawi zina, izi zimachitika kupyolera mu singano imodzi ndipo kupatukana ndi kubwereza kumachitika m'magulu ang'onoang'ono.
Kodi Mumamva Bwanji?
Zonsezi zomwe tazitchula pamwambazi zimachitika mosalekeza.
Zochitika kwa wodwala ndizofanana ndi zitsulo ziwiri / za catheters zomwe zimakhalapo ndipo zimayang'ana magazi kuchoka kumbali imodzi, kupyolera mu makina, ndi kubwerera kumbali inayo. Njira yonse imatenga maola awiri ndi 4 kuti amalize.
Anthu amamva ngati amadzimva pang'ono kapena osamvetsetsa. Komanso, anthu ena amanena kuti anticoagulant yowonjezera magazi kapena ena omwe amachotsa madzi omwe amagwiritsidwa ntchito chifukwa chogwedeza kapena zokopa ndi singano zowawa zala ndi zala. Pangakhalenso kukoma kowawa pakamwa. Pangakhale phokoso lochepa ndi kutopa.
Ngozi
Zotsatira zoyipa za plasmapheresis sizodziwika. Chodabwitsa kwambiri cha izi ndi anaphylaxis, chomwe chimakhala choopsa kwambiri kwa madzi omwe amalowa m'malo mwa madzi. Ichi ndi chimodzi mwa zifukwa zomwe kusinthana kwa plasma kumachitidwa pamakhalidwe oyang'aniridwa.
Matenda ochokera ku plasmapheresis ndi osowa, makamaka kugwiritsa ntchito zipangizo zamakono zatsopano ndi madzi osasintha. Komabe, anthu angakhale ovuta kutenga chinachake pambuyo pa plasmapheresis, pamene maselo ambiri am'thupi amachotsedwa, ndipo munthuyo akhoza kukhala wosazindikira mosavuta.
Zina mwa zotsatira zake zingakhale:
- Zowonongeka, zomwe zimawoneka ngati kuzizira, malungo kapena kuthamanga pang'ono
- Kuchulukitsa magazi
- Magazi a magazi
- Kusagwirizana kwa mtima
- Ikani magazi
- Kupuma pang'ono
- Kudandaula kapena kutupa
Pansi
Plasmapheresis kawirikawiri ndi njira yabwino komanso yosamalidwa bwino. Izi zikunenedwa, sizimagwiritsidwa ntchito nthawi zambiri mu MS - pomwe munthu akulephera kubwezeretsa kachilombo ka HIV ndipo sakulabadira kachitidwe ka mankhwala ka steroid. Plasmapheresis sagwiritsidwa ntchito pochizira MS wapamwamba kapena wachiwiri.
Zotsatira
Cortese I et al. Ndondomeko yochokera ku maumboni: Plasmapheresis mu matenda a ubongo: Report of Therapeutics and Technology Assessment Committee ya American Academy of Neurology. Neurology . 2011 Jan 18; 76 (3): 294-300.
Fridey JL, Kaplan AA. "Malemba ndi njira zamankhwala othandizira mankhwala a plasma." Zaposachedwa. Kusinthidwa pa March 31, 2010.