Odwala Amene Angapeze Mpumulo Wosatha Angayankhe kwa ER Opioid Analgesics
Mpumulo Wopweteka Wopweteka wa Osteoarthritisi Umapangitsa Mavuto Enanso
Malinga ndi lipoti la nyuzipepala ya American Journal of Therapeutics , kuvutika kwanthaŵi yaitali komwe kumakhudzana ndi matenda a osteoarthritis kumakhudza wodwalayo mwa kuchititsa kuti:
- khalidwe lochepa la moyo
- kugona kochepa kapena kosokonezeka
- maubwenzi amtundu umene amavutika
- kuchepa kwachithunzi (kulingalira, kukumbukira)
- zofooka pazochitika za tsiku ndi tsiku
- kuchepetsa kuchepa
- kuda nkhawa ndi kuvutika maganizo
Kusokoneza tulo - chifukwa cha ululu - ndilo vuto lalikulu kwa odwala osteoarthritis. Ambiri odwala matenda a m'magazi ali ndi vuto loyamba kugona, kukonzekera kugona, kapena kudzuka. Kuti mupirire mavuto onsewa, ululu wa osteoarthritis uyenera kuyendetsedwa bwino.
Odwala ambiri a m'magazi amalandira chithandizo chamtundu wina , koma nthawi zambiri samapeza kupweteka kokwanira. Zotsatira zaphunziro zasonyeza kuti odwala osteoarthritis oposa 3,100, 25% amanena kuti sakondwera ndi mankhwala awo opweteka. Pa gulu losakhutira, 63% adanena kuti mpumulo umakhala wosaperewera pomwe 17% adanena za zotsatirapo.
Kugwiritsa ntchito mapiritsi pa ndondomeko ya May, Pangani Kukula
Odwala opweteka osatha, ndi bwino kumwa mankhwala opweteka pa nthawi. Cholinga cha ndondomeko ya mankhwala opweteka nthawi zonse ndikutenga mankhwala omwe amachititsa kupweteka musanafike.
Vuto ndilo, chifukwa cha zifukwa zosiyanasiyana, odwala matenda a osteoarthritis samamwa mankhwala opweteka panthawi yake, ndipo amalola kupweteka kubwerera - ndiye amatsata ululu ndi mlingo wina. Mankhwala opweteka kwa nthawi yayitali kapena othandizira angapindule bwino kwa odwala omwe amavutika kuti atsatire ndandanda.
Menyu ya Analgesics - Kodi Muyenera Kusankha Ndani?
Odwala atsopano odwala matenda a osteoarthritis amayamba kuyesa acetaminophen - amadziwika kuti analgesic yoyamba ya osteoarthritis. NSAIDs (mankhwala osakanizika ndi mankhwala osakanizidwa) komanso COX-2 inhibitors amagwiritsidwanso ntchito kuchepetsa ululu wa osteoarthritis, makamaka ngati mukusowa chithandizo chambiri kusiyana ndi acetaminophen. Kuti amve kupweteka kwambiri, madokotala amaganiza kuti mankhwala opioid osakanizidwa monga tramadol ndi ogioid analgesics (olamulira zinthu).
Kodi Ndizovuta Zotani Zopweteka?
Mankhwala opweteka kwambiri amatha kuloledwa, ophweka, ndikupatsanso ululu wozungulira maola. Zidzakhala ndi mphamvu zochepa zowononga komanso zowonjezereka zowonongeka komanso zowonongeka ndi kugwiritsa ntchito nthawi yayitali. Kodi mankhwala otsekemera oterewa (ER) amatha kupweteka kwambiri? Kwa odwala ena, inde. Koma odwala pogwiritsira ntchito ER opioid analgesics ayenera kudziwa zomwe zingakhale zovuta ndipo ayenera kugwiritsa ntchito mankhwalawa monga momwe akufunira.
ER Opioid Analgesics Ikhoza Kukhala Yogwira Ntchito Pamene Ikugwiritsidwa Ntchito Mwabwino
ER morphine, ER oxymorphone, CR (kutulutsidwa kutuluka) oxycodone, ER transdermal fentanyl, ndi ER tramadol ndi ena mwa maulendo owonjezera a opioid omwe angathe kuganiziridwa kuti athetse ululu wa osteoarthritis.
Ofufuza apeza kuti once acetaminophen ndi NSAID sakhala ogwira ntchito, kapena osteoarthritis ikuipiraipira - ER tramadol akhoza kukhala njira yabwino yotsatira - isanayambe kuyesedwa, analgesics ya opioid.
ER tramadol ali ndi ubwino wina pamwamba pa ma analgesics ena a ER. Chifukwa chimodzi, tramadol imabweretsa zotsatira zochepa kusiyana ndi ma opioids ena. Kuda nkhawa ndi kugwiritsa ntchito mankhwala osokoneza bongo, kuledzera, kulekerera, ndi kuchotsa zizoloŵezi za opioid analgesics. Ma analgesics opioid (kuphatikizapo ER opioid analgesics) amatha kuyambitsa mavuto, kusokonezeka, ndi kudzimbidwa, makamaka okalamba.
Monga mankhwala alionse, odwala ayenera kukambirana ndi adokotala za ubwino wotsatizana ndi zovuta za kutenga ma ojoni opioid.
Ngakhale kuli kofunikira kwa analgesics opioid kwa odwala ena omwe sanayankhe bwino kapena kusiya kuyankha kwa acetaminophen, NSAIDs, ndi tramadol - analgesics opioid si oyenera kwa wodwala aliyense.
Mabaibulo a morphine, fentanyl, oxymorphone, ndi oxycodone a ER akukonzedwa, ma analgesics othawikirapo:
- ER morphine amasonyezedwa kuti azitha kupweteka kwambiri kwa odwala ena osteoarthritis. Cholinga cha kumwa mankhwalawa ndi kuzungulira kupweteka kwa nthawi ndi kusintha kwakukulu kwa moyo.
- ER oxymorphone inawerengedwa ngati yabwino kwambiri, yabwino kwambiri, kapena yabwino mwa odwala pafupifupi 80%. Anapereka mpumulo wopweteka kwambiri komanso kusintha kwa opaleshoni kwa odwala omwe ali ndi ululu wosaneneka wa osteoarthritis.
- Khungu la oxycodone limathandiza kuchepetsa ululu umene umayamba chifukwa cha osteoarthritis komanso kusintha moyo. Komabe, oxycodone ndi mankhwala omwe nthawi zambiri amakhala atsopano pa nkhani yogwiritsira ntchito mankhwala osokoneza bongo.
- ER transdermal fentanyl ayenera kugwiritsidwa ntchito ndi odwala omwe akulandira kale opioid ndi kusonyeza kulekerera opioid. Ndizothandiza kuthetsa ululu woopsa wa osteoarthritis.
Simuyenera kukhala ndi ululu wosatha. Kambiranani ndi adokotala zakumva ululu ndipo musaiwale kufunsa za kutulutsidwa kwa ma analgesics opioid. Si njira yabwino yothetsera chithandizo kwa wodwala aliyense - koma kodi ndi njira yopangira chithandizo kwa inu?
Chitsime:
Kupwetekedwa Kwambiri kwa Osteoarthritis: Kuganizira Zosankha Opioid Yowonjezedwa Kwambiri. American Journal of Therapeutics 15,241-255 (2008). Gibofsky, Allan ndi Barkin, Robert L.