Januvia (sitagliptin phosphate) amavomereza mankhwala ovomerezeka pamlomo amavomereza ndi US Food and Drug Administration pofuna kuyang'anira matenda a shuga a mtundu wa 2 . Ndiyo yoyamba m'gulu la mankhwala otchedwa DPP-4 inhibitors. Januvia amalepetsa shuga ya magazi mwa kutseka puloteni wotchedwa dipeptidyl peptidase IV kapena DPP-4.
Kodi mtundu wa shuga ndi wotani?
Mtundu wa shuga wa 2, womwe umatchedwa kuti munthu wamkulu kapena wodwala matenda a shuga, ndi matenda aakulu omwe amakhudza momwe thupi lanu limagwirira ntchito shuga (shuga), thupi lanu ndi lofunika kwambiri.
Ndi mtundu wa shuga wachiwiri, thupi lanu limatsutsa zotsatira za insulini-hormone yomwe imayendera kayendedwe ka shuga m'maselo anu-kapena sabala insulini yokwanira kuti mukhale ndi mlingo wabwinobwino wa shuga.
Zowonjezereka kwa anthu akuluakulu, mtundu wa shuga 2 umakhudza kwambiri ana ngati kunenepa kwambiri kwaunyamata kukuwonjezeka. Palibe mankhwala a shuga wa mtundu wa 2, koma mukhoza kuthetsa vutoli mwa kudya bwino, kuchita masewera olimbitsa thupi, ndi kukhala ndi thanzi labwino. Ngati zakudya ndi masewero olimbitsa thupi sali okwanira kusamalira shuga lanu, mumadwala mankhwala a shuga kapena mankhwala a insulini.
Momwe Januvia Amagwirira Ntchito
DPP-4 imayambitsa kuthetsa mapuloteni omwe amachititsa maselo opangidwa ndi insulini akamadya. Ngati DPP-4 imaletsedwa, ndiye kuti mapuloteni amatha kutulutsa insulini kwa nthawi yayitali, motero amachepetsa mlingo wa shuga m'magazi.
Januvia anawonetsa zotsatira zabwino m'mayesero atsopano onse kuphatikizapo mankhwala ena, monga metformin, komanso palokha.
Amaperekedwa kwa mtundu wa shuga 2.
Kwa anthu ena, zakudya, masewera olimbitsa thupi, ndi mankhwala ochiritsira sizongokwanira kuti magazi a shuga azikhala bwino. Januvia wakhala akuyesedwa mu mayesero a zachipatala pothandizira kuchepetsa iwo pamene njira zachikhalidwe sizikwanira. Zakudya ndi masewera olimbitsa thupi akadakali zofunikira kuwonjezera pa chithandizo chamankhwala, komabe.
Januvia amagwira ntchito popititsa patsogolo kutulutsa kwa insulini. Kuopsa kwa hypoglycemia sikungatheke chifukwa Januvia imangogwira ntchito ngati pakufunika. Mwachitsanzo, ngati palibe shuga m'magazi, ndiye kuti palibe chomwe chikuchitika kuchokera ku Januvia. Koma, atatha kudya pamene magulu a shuga akukwera, ndiye Januvia adzagwira ntchito kuti achepetse gawolo.
Komanso, asayansi apeza kuti palibe chiopsezo chochepetsera kulemera kwa January, mosiyana ndi mankhwala ena a shuga.
Zotsatira Zotsatira
Zotsatira zambiri zomwe zimakhalapo zimaphatikizapo matenda opuma opuma, chifuwa chachikulu, ndi / kapena mutu.
Januvia amasinthidwa kupyolera mu impso. Anthu omwe adachepetsa ntchito yothanzila nsomba angafunikire kuti January awo asinthidwe ndi dokotala wawo ku mlingo wochepa. Ntchito yamatenda ayenera kuyesedwa asanatenge Janvia.
Chitsime:
US Food and Drug Administration. FDA imavomereza chithandizo chatsopano cha shuga. Oct. 2006.