Folate ndi madzi osungunuka, vitamini B omwe ndi ofunikira thupi ndi ntchito zosiyanasiyana kuphatikizapo kupanga maselo atsopano ndi kupanga maselo ofiira.
Icho chimatchedwa chochita ngati chimapezeka mu zakudya, monga nyemba, zipatso, ndi masamba obiriwira. Folic acid ndi mankhwala omwe amapezeka mu zakudya zambiri (monga mkate ndi tirigu) komanso ngati chowonjezera.
Anthu omwe ali ndi matenda opatsirana a m'magazi (IBD) ali pachiopsezo chosowa kwa anthu, makamaka omwe amatenga methotrexate kapena sulfasalazine .
Chifukwa Chachikulu cha Folate
Thupi silingathe kupanga folate kapena folic acid, kotero ilo liyenera kupezeka kuchokera ku chakudya ndi zowonjezereka. Folate ndi vitamini B yomwe ili yofunikira kale komanso panthawi ya mimba chifukwa imagwiritsidwa ntchito mu selo ndi kulumikiza. Kudya mokwanira koyenera kumathandiza kupewa nthenda yamtundu wa neural monga spina bifida mu mwana.
Mankhwalawa amafunikanso kuti thupi likhale ndi mavitamini abwino a amino acid homocysteine, omwe amafunikira thupi kuti likhale ndi mapuloteni. Popanda masewero okwanira, homocysteine adzamanga m'thupi. Matenda apamwamba a homocysteine amayamba ndi matenda a mtima.
Mankhwala angathandizenso kupewa khansa poteteza kusintha kwina mu DNA ya thupi. Chifukwa chothandizira amafunika kuti apange maselo ofiira a magazi, kupeza masewera okwanira n'kofunikanso kuteteza kuchepa kwa magazi m'thupi .
Chifukwa chiyani odwala a IBD ali pangozi ya kuchepa kwa folate
Anthu omwe ali ndi matenda a Crohn m'matumbo awo aang'ono amakhala pachiopsezo cha mavitamini ndi minerals ambiri. Fungoli limaphatikizidwa ndi pakati ndi kumapeto kwa matumbo aang'ono, jejunum ndi ileum.
Sulfasalazine ndi methotrexate ndi mankhwala awiri ogwiritsira ntchito IBD omwe angasokoneze mitsempha ya mankhwala.
Zifukwa zina zomwe anthu osauka amachita zimakhala monga kumwa moŵa, matenda a chiwindi, komanso kugwiritsa ntchito mankhwala a antiticonvulsant, metformin , triamterene, kapena barbituates.
Kodi Munthu Wonse Amene Ali ndi IBD Ali Pangozi Yoperewera Kwambiri?
Kafukufuku wina adawonetsa kuti odwala atsopano omwe ali ndi kachilombo ka HIV ali ndi miyeso yapamwamba kuposa ana omwe alibe IBD. Olembawo adadabwa, atapatsidwa kuti atsimikiziridwa kuti ali oona pakati pa odwala akuluakulu a IBD. Maseŵera a ana omwe ali ndi IBD angafunike kuyang'aniridwa kuti adziwe ngati zowonjezereka zili zofunikadi.
Odwala a IBD ali pachiopsezo cha homocysteine. Homocysteine ndi amino acid, ndipo maseŵera omwe ali apamwamba kwambiri amagwirizanitsidwa ndi magazi ndi zipsinjo za mtima. Kwa anthu omwe ali ndi IBD, kusowa kwa masewera kungakhale kosayenerera kwa homocysteine. Kafukufuku wina wasonyeza kuti kuwonjezeka kwa homocysteine kwa anthu omwe ali ndi IBD kungakhale chifukwa cha mavitamini B12 ochepa, osati m'magulu otsika.
Zimene Mungachite
Pofuna kuteteza vuto loperewera, zingakhale bwino kuti anthu omwe ali ndi IBD atenge supplement folic acid. Anthu amene amatenga sulfasalazine ndi methotrexate, makamaka, angafunike kwambiri folic acid. A folic acid supplement ya 1000 micrograms (1 milligram) pa tsiku nthawi zambiri amalimbikitsa anthu omwe ali pachiopsezo chosowa.
Funsani dokotala wanu kuti mudziwe kuchuluka kwa folic acid yomwe mumasowa tsiku ndi tsiku komanso ngati mukufuna kutenga mankhwala enaake.
Zakudya zina zomwe zili ndi follic acid kapena folic acid ndi:
- Katsitsumzukwa
- Ng'ombe ya njuchi
- Burokoli
- Cowpeas
- Mbewu zapamwamba, mpunga, Zakudyazi za mazira, ndi mkate
- Nyerere Yaikulu Kumpoto
- Nyemba zobiriwira
- Sipinachi
Zotsatira:
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Heyman MB, Garnett EA, Shaikh N, et al. "Anthu odwala matenda opatsirana omwe amatulukira matenda opatsirana." Am J Clin Nutr 2009 Feb; 89: 545-550.
Ofesi Zowonjezera Zakudya. "Chakudya Chakudya Chakudya: Zolemba." National Institutes of Health 15 Apr 2009.
Romagnuolo J, Fedorak RN, Dias VC, Bamforth F, Teltscher M. "Hyperhomocysteinemia ndi kutupa matenda a m'magazi: kufalikira ndi kufotokozera m'maphunziro." Am J Gastroenterol 2001 Jul; 96: 2143-2149.
MASE ML. "Zakudya za antioxidants, oxidised LDL ndi homocysteine." Library ya Oulu University 2003.
Vagianos K, Bector S, McConnell J, Bernstein CN. "Kuyezetsa zakudya kwa odwala omwe ali ndi matenda opatsirana." JPEN J Parenter Enteral Nutriti 2007 Jul-Aug; 31: 311-319.