Kugwiritsa ntchito, zotsatira zoyipa, mlingo, ndi kugwiritsa ntchito Methotrexate Mukutenga
Kodi Methotrexate N'chiyani?
Methotrexate ndi gulu la mankhwala omwe amadziwika ngati antineoplastics. Mankhwala opatsirana pogonana amalepheretsa njira zamakono za thupi, monga kupanga DNA ndi kugawa maselo. Zimathandiza pa matenda opatsirana khansa, chifukwa zimathandiza kuti maselo a khansa asapitirire. Methotrexate ingaperekedwe pofuna kuthana ndi matenda a akylosing spondylitis, nyamakazi ya nyamakazi, psoriasis, ndi matenda a Crohn
Kodi Methotrexate Imatengedwa Bwanji?
Methotrexate iyenera kutengedwa chimodzimodzi monga momwe adanenera. Thupi lidzakwaniritsa mlingo wa zosowa za wodwala aliyense. Methotrexate ingaperekedwe ngati piritsi, kulowetsedwa kapena jekeseni. Ngati atengedwa kamodzi pa sabata, ndibwino kuti mutenge tsiku lomwelo.
N'chifukwa Chiyani Methotrexate Inalembedwa?
Chifukwa methotrexate imateteza maselo a metabolism, imaperekedwa kuti zikhale zovuta pamene maselo osadziwika bwino akukula, monga psoriasis kapena khansara. Methotrexate yapezeka kuti ikuthandiza pochiza matenda ena a Crohn ndi matenda a nyamakazi . Methotrexate imagwiritsidwanso ntchito poyambitsa kupititsa padera mu ectopic pregnancy.
Ndani Asatenge Methotrexate?
Uzani dokotala wanu ngati mwakhalapo ndi izi:
- Pakali pano ali ndi pakati
- Matenda a impso
- Matenda a chiwindi kapena chibwibwi
- Matenda a zilonda kapena fibrosis
- Matenda a Neurologic
- Matenda opatsirana
Kodi Zotsatirapo Zili Zotani?
Zotsatira zoyipa za methotrexate zikuphatikizapo mutu, kugona, kuyabwa, kuthamanga kwa khungu, chizungulire, ndi kutaya tsitsi.
Zotsatira zoyipa zikuphatikizapo poizoni wa chiwindi, fupa la fupa kapena, kawirikawiri, mapapo. Onani tsamba la zotsatira za methotrexate za mndandanda wathunthu.
Kodi Pali Kuyanjana Kwa Chakudya?
Mowa sayenera kudyedwa pamene akutenga methotrexate, chifukwa zingayambitse chiwindi, zomwe zimayambitsa chiwindi.
Kodi Ndi Mankhwala Otani Amene Angagwiritse Ntchito Mankhwalawa?
Anthu omwe amatenga methotrexate ayenera kupewa katemera ndi kachilombo ka moyo. Methotrexate imayambitsa chitetezo cha thupi kuti chitetezedwe, kotero katemera wa moyo wamoyo ukhoza kubweretsa matenda m'malo mwa chitetezo cha mthupi.
A FDA amalimbikitsa kusamala potenga methotrexate pamodzi ndi proton pump inhibitor (PPI) , zomwe ndi mankhwala omwe amathandiza kuchepetsa kuchuluka kwa asidi mmimba. Ma PPI ambiri amaphatikizapo Prilosec ( omeprazole), Nexium (esomeprazole) , ndi Protonix (pantoprazole). Chodetsa nkhaŵa makamaka chikuwonetsedwa kwa omwe akutsitsa mlingo wa methotrexate. Vuto ndilokuti PPI ikhoza kuwonjezera ma seramu (kuchuluka kwa magazi) a methotrexate. Mpweya waukulu wa seramu ungatanthauze kuti pali mankhwala ofooketsa a methotrexate omanga thupi. Zotsatira zonse za mgwirizanowu zikupitilizidwanso, koma pakali pano a FDA atulutsa chenjezo lokhudza methotrexate pamodzi ndi PPI.
Methotrexate ingagwirizane ndi mankhwala otsatirawa:
- Mankhwala a nyamakazi (ibuprofen, Advil, Motrin, Naprosyn, Voltaren, Lodine)
- Aspirin kapena salicylates ena
- Azathioprine (Imuran)
- Bismuth subsalicylate (Pepto Bismol)
- Carbenicillin (Geocillin)
- Cholestyramine (Questran)
- Ochepa magazi (Coumadin)
- Cyclosporine (Sandimmune, Neoral)
- Digoxin (Lanoxin)
- Etretinate (Tegison)
- Phenytoin (Dilantin)
- Probenecid
- Proton pump inhibitors (PPIs)
- Mankhwala a Sulfa (Bactrim)
- Thiazide diuretics (Dyazide, hydrochlorothiazide)
Kodi Methotrexate Ali Otetezeka Pakati pa Mimba?
A FDA apanga methotrexate ngati mtundu X mankhwala. Izi zikutanthauza kuti maphunziro a zinyama kapena amayi apakati atsimikizira umboni wokwanira wa zovuta za mwana. Methotrexate sayenera kugwiritsidwa ntchito panthawi yomwe imatenga mimba chifukwa ikhoza kuyambitsa kuperewera kwa amayi kapena kubereka kwa mwana wosabadwa. Amuna ayenera kusiya methotrexate kwa miyezi itatu asanayambe kutenga pakati.
Azimayi ayenera kusiya methotrexate pa njira imodzi yodzaza ma ovulation asanabadwe. Methotrexate imadutsa mkaka wa m'mawere, ndipo imakhudza mwana wakhanda. A FDA amalimbikitsa kuti mankhwalawa asagwiritsidwe ntchito pazaka za kubala msinkhu pokhapokha "pali umboni wodalirika wosonyeza kuti phindu likhoza kuyembekezera zoopsa zomwe zimaganiziridwa."
Kodi Methotrexate Ingakhale Motetezeka Kwambiri Motani?
Methotrexate ingatenge milungu ingapo kuti ikwaniritse matenda a Crohn. Izi zimangotengedwa kwa nthawi yaitali (miyezi kapena zaka) pansi pa kuyang'anitsitsa kwa dokotala.
Chitsime:
Hospira, Inc. " Methotrexate Injection, USP ." FDA.gov. Oct 2011.
Mauthenga a Mankhwala a Micromedex. "Methotrexate (Ndikamwa)." Zolemba Zaumoyo Dec 2015.