Thupi lathu liri ndi mahomoni omwe amachititsa mbali zonse za thupi, ndipo izi zikuphatikizapo kudya ndi kulemera kwa malamulo. Amapezeka mahomoni ambiri omwe amakhudza njala ndi chitukuko kapena kuchepetsa kunenepa kwambiri . Pali mahomoni akuluakulu awa: ghrelin , leptin, insulini, ndi peptide YY (PYY). Nkhaniyi ikufotokoza za leptin.
Kodi Leptin N'chiyani?
Mwachidule, leptin ndi hormone imene imalepheretsa kudya.
Icho chimatchedwa "chosamalitsa" pa chifukwa ichi. Leptin imapangidwa ndi maselo adipose (mafuta). Momwe zimakhalira ndizofanana ndi mafuta a thupi. Pamene mafuta a thupi amawonjezeka, momwemonso amithenga a leptin, omwe amatumikira kuti athetse chilakolako ndi kuonjezera mlingo wamagetsi. Pamene mafuta a thupi amagwa, momwemonso mawere a leptin, ndi kukhumba kwa kudya kumachotsedwa, kuwonetsera kwa thupi kuti ndi nthawi yoti adye kachiwiri. Poyambirira, izi zinkathandiza cholinga choletsa njala.
Nthawi zina Leptin amaganiza kuti ghrelin ndi mnzake chifukwa ghrelin ( nthenda inayake yoletsa kudya, yomwe imabadwa m'mimba ndi duodenum) imalimbikitsa chilakolako chofuna kudya. Chifukwa leptin ikhoza kuchepetsa kudya chakudya mwa kuchepetsa chilakolako chofuna kudya, ikhoza kuchepetsa kulemera kwa thupi; Kulimbana ndi zimenezo, chifukwa ghrelin ikhoza kuwonjezera chakudya chokwanira chifukwa chofuna kudya, imatha kulemetsa ndi kunenepa kwambiri.
Mu 1994, jini yomwe imatulutsa leptin, yomwe imadziwika kuti obeni ( OB ), inapezedwa ndi Zhang ndi anzake mu mbewa.
Leptin wakhala akugwira ntchito zosiyanasiyana, kuphatikizapo mayankho a chitetezo cha mthupi ndi kutupa, zomwe zimathandiza kuti munthu ayambe kutha msinkhu.
Kodi Zimakhudza Mipata ya Leptin?
Ofufuza apeza makhalidwe angapo ndi zinthu zomwe zingawonjezere kapena kuchepetsa miyeso ya leptin m'thupi.
Kukula ndi kuchuluka kwa chakudya kumawoneka kuti kumathandizira kutulutsa leptin kuchokera minofu ya adipose. Komanso, chakudya chofunika ndi chofunikira. Mwachitsanzo, m'maphunziro ena, chakudya chokhala ndi mafuta ochepa chimawoneka kuti chimachititsa kuti leptin ikhale yovuta kuposa chakudya chambiri. Palinso umboni wakuti odwala ambiri akhala odwala leptin, kapena osagonjetsedwa ndi zotsatira za leptin, motero njira yowonongeka ya chilengedwe yomwe imauza thupi kuti nthawi yoti asiye kudya yasokonezedwa.
Kugona pang'ono kungapangitsenso mawere a leptin, zomwe zimapangitsa kuti muzitha kuchepa komanso chilakolako chachikulu (kugwirana ntchito ndi ghrelin, monga taonera pamwambapa). Kupeza maola asanu ndi awiri mphambu asanu ndi anayi osapumitsa osasokonezeka usiku uliwonse kumawoneka kuti kumathandiza kusunga ma leptin pomwe akuyenera kudya.
Monga momwe tingaganizire, chifukwa chakuti amatha kuchepetsa kulemera kwa thupi, kafukufuku akuyang'ana njira zosiyanasiyana zogwiritsira ntchito leptin ndi ntchito zake za mankhwala a pharmacologic akhala akupitilira kwa nthawi ndithu ndipo ali mbali ya kufufuza kosatha mankhwala ochepetsa kunenepa kwambiri.
Zotsatira :
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