IgA Nephropathy imasiyana mosiyana ndi matenda omwe amachititsa kuti thupi likhale lopweteka kwambiri. Choncho, mankhwala sangakhale ofunikira kwa wodwala aliyense ndipo muyenera kulankhula ndi katswiri wa zachipatala chodziwitsa njira yabwino.
Kuchiza Odwala Oopsa
Kawirikawiri, odwala omwe ali ndi zizindikiro zotsatirazi amaonedwa kuti ndiwopseza kwambiri kufooka kwa ntchito ya impso:
- Odwala ndi otsika GFR kapena kukwera mu creatinine (izi ndizoyeso zovuta za ntchito yanu impso)
- Anthu omwe ali ndi kuthamanga kwambiri kwa magazi
- Odwala omwe amawonongeka kwambiri ndi mapuloteni mu mkodzo
- Odwala omwe ali ndi zifukwa zina zomwe amadera nkhawa za impso za impso (kupyola muyeso ya nkhani ino)
Ngati mukuganiza kuti mukugwirizana ndi maguluwa, pali njira zingapo zomwe mungakonde kuziganizira:
- Mankhwala otchedwa Angiotensin-Kutembenuza Mavitamini a Enzyme kapena Angiotensin Receptor Blockers: Awa ndiwo mankhwala omwe amagwiritsidwa ntchito mobwerezabwereza (mwina mumamva mayina monga lisinopril kapena losartan). Komabe, mankhwalawa samangowonjezera kuthamanga kwa magazi, amathandizanso impso kuti azigwira ntchito chifukwa choteteza chitetezo m'matini (zomwe zimawonekera kwa odwala IgA nthenda). Izi zimathandizanso chifukwa odwala omwe ali ndi nthenda ya IgA angakhale ndi vuto la kuthamanga kwa magazi. Choncho, pokhapokha ngati wodwala sangathe kulekerera, nthawi zambiri amawoneka kuti ndi mankhwala oyamba omwe amachiza kuthamanga kwa magazi kwa odwala okhala ndi IgA nthenda yoperewera m'thupi.
- Mafuta a nsomba / mankhwalawa-mphamvu ya omega-3 fatty acids: Mafuta a nsomba awonetsa lonjezo kwa odwala omwe ali ndi matenda a IgA, mwina chifukwa cha zochita zawo zotsutsa-kutupa. Komabe, mphamvu ya nsomba yamtengo wapatali sinayambe yakhazikitsidwa bwino. Mchitidwewu ndiwugwiritsidwe ntchito pamodzi ndi mankhwala ena malinga ngati wodwalayo akulekerera. Madokotala ambiri amakhulupirira kuti mafuta a nsomba sangakhale ovulaza ndipo amatha kuwombera.
- Glucocorticoids / steroids: Chitsanzo chofala kukhala chinachake chotchedwa "prednisone." Odwala omwe ali ndi matenda aakulu ndi odwala omwe amavutika ndi impso amasonyeza kuti kutupa kwakukulu kungapindule ndi mankhwalawa. Mankhwalawa amachititsa kuti chitetezo cha thupi chiteteze thupi komanso chitetezo cha chitetezo cha thupi kotero kuti chingathandize odwala omwe ali ndi matenda a IgA (popeza tikudziŵa kuti chitetezo cha mthupi chimapweteka impso pankhaniyi). Ndikofunika kuzindikira kuti steroids si aliyense. Odwala omwe ali ndi matenda opepuka sangapindule nawo ndipo chiwopsezo chotenga phindu sichingawakonde (popeza mankhwalawa amabwera ndi zotsatira zoopsa monga kulemera, shuga wambiri wamagazi, kukwera kwa magazi, kutaya mafupa, ndi zina). Mosiyana ndi zimenezi, odwala omwe matenda aakulu amakhalapo kwa nthawi yayitali ndipo atha kuwonongeka kosatha komanso kupweteka kwa impso sangathandizenso ndi steroids. Izi sizili zovuta kumvetsa ngati mwazindikira kuti steroids ndi zomwe timagwiritsa ntchito "kutulutsa moto wa kutupa." Mwa kuyankhula kwina, pamene moto wagwira ntchito yake ndikuwonongeratu impso ndikuzisiya ndi minofu yakufa, kupereka wina mankhwala opatsirana kumakhala ngati kutsanulira madzi pa nyumba yomwe yatentha kale. Izo sizigwira ntchito.
- Mycophenolate mofetil: Ichi ndi mankhwala atsopano osamalidwa bwino omwe amawerengedwa ngati wothandizila omwe angapindule odwala ndi matenda a IgA. Koma pakalipano, sikunayamikiridwa ngati woyang'anira mzere woyamba kupatula kuti palibe umboni weniweni.
- Cyclophosphamide, Azathioprine, ndi zina: Izi ndizo mankhwala ena omwe amagwiritsidwa ntchito nthawi zosiyanasiyana pochiza matenda a IgA. Kugwiritsira ntchito kwawo sikungagwiritsidwe ntchito kwa wodwala komanso kachiwiri, mwina sangakhale opindulitsa kwa odwala kumene kuwonongeka kwakukulu kwachitika kale.
Lankhulani ndi katswiri wanu wamatsenga za zomwe mungachite bwino.