Thupi lathu liri ndi mahomoni omwe amachititsa mbali zonse za thupi, ndipo izi zikuphatikizapo kudya ndi kulemera kwa malamulo. Pali mahomoni angapo omwe adapezeka omwe amakhudza chitukuko cha kunenepa kwambiri ; imodzi mwa izi ndi ghrelin.
Kodi Ghrelin Ndi Chiyani?
Mwachidule, ghrelin ndi hormone yomwe imalimbikitsa chilakolako. Choncho, chilichonse chomwe chimawonjezera ma ghrelin chimawonjezera chilakolako, ndipo izi zikhoza kulemetsa kulemera ndi kunenepa kwambiri.
Ghrelin amapangidwa makamaka ndi mmimba ndi duodenum . Zapezeka kuti zimagwira nawo ntchito yomwe imadziwika kuti njala ya nthawi yamadzulo, komanso kuwonetsetsa kulemera ndi kuwonongeka kwa nthawi yaitali.
Nthaŵi zina Ghrelin amalingalira ngati mnzake wa leptin chifukwa leptin ( nthenda ina yoletsa kudya, yomwe imapangidwa ndi minofu ya adipose) imalepheretsa chilakolako chofuna kudya pamene miyezo yake ikuwonjezeka.
Akatswiri ofufuza atulukira kuti kulowetsa ghrelin mu makoswe kumapangitsa kuti azidyetsa komanso kumawonjezera kunenepa kwa makoswewa, chidwi chinakula pofotokozera zomwe ghrelin ingakhoze kusewera mu mliri wa kunenepa kwambiri kwa anthu.
Kodi Ndi Zowonjezereka Ziti Ghrelin?
Ofufuza apeza makhalidwe angapo ndi zinthu zomwe zingawonjezere kapena kuchepetsa miyeso ya ghrelin m'thupi. Khalidwe limodzi limene limapangitsa kuti ma ghrelin asatenge mokwanira . Kwa nthawi yaitali, kuchepa kwa maola asanu ndi awiri mphambu asanu ndi awiri (7) asanu ndi asanu ndi awiri (7) osasokonezeka osagona kusokonezeka nthawi zonse kungapangitse kuchuluka kwa ghrelin levels-zomwe zimasintha kukhala kudya kwakukulu, kudya kwa kalori, ndi kupindula.
Mosiyana, kugona mokwanira usiku uliwonse kumachepetsa ghrelin, ndipo potero kumachepetsa chilakolako. Pamene zikuchitika, pali chifukwa chogwiritsira ntchito "midzi munchies" pakati pa usiku, pambuyo pake!
Pamalo odyera zakudya, kudya zakudya zamadzimadzi kwambiri, makamaka pokhala opanda mapuloteni okwanira ndi mchere, zingayambitse kuchuluka kwa ghrelin levels, chifukwa ndi mapuloteni ndi mapiritsi apamwamba omwe angachepetse chiwerengero cha ghrelin mpaka momwe ubongo wa munthu umakhalira chizindikiro chakuti thupi wadya mokwanira ndipo limauza thupi, kudzera mwa kukhutira, kuti ndi bwino kusiya kudya.
Ichi ndi chifukwa chake ambiri amapeza chipatso cha chipatso cha mbatata pambuyo pa chipatso cha mbatata kapena mikate yofiira kwambiri yoyeretsedwa popanda kumverera kuti zakudya zonsezi sizikhala ndi mapuloteni okwanira kapena zowonjezera kuti zichotse zizindikiro za ghrelin ku ubongo.
Mwa kuyankhula kwina, ndi kudya kwazakonzedwa bwino, chifukwa ubongo sunapeze chizindikiro chakuti thupi latenga zakudya zowonjezera zofunika, zimapangitsa thupi kuti lidye, mwa kudya kosakhutira. Kawirikawiri, magulu a ghrelin ayenera kuwonjezeka musanafike nthawi yamadzulo (kukudziwitsani kuti ndi nthawi yoti mudye), ndi kuchepetsa nthawi yatha. Komabe, kumwa madzi okonzedwa bwino, monga taonera pamwamba, kukhoza kusokoneza izi.
Kodi Amachepetsa Ghrelin?
Monga momwe mungakwaniritsire pa zokambirana pakalipano, makhalidwe omwe nthawi zambiri amagwirizana ndi moyo wathanzi komanso kudya zakudya zowonjezera angathe kusunga ma ghrelin. Izi zimaphatikizapo kudya zipatso ndi ndiwo zamasamba ndi zakudya zina zapamwamba (monga mbewu zonse); kudya zakudya zomwe zimakhala ndi zakudya zambiri (monga zipatso ndi ndiwo zamasamba, komanso zakudya zomwe zimapatsa mapuloteni athunthu); ndi kugona mokwanira. Zotsatira zimatsutsanabe ngakhale ngati opaleshoni yopitirira opaleshoni imapangitsa kuchepa kwa ghrelin.
Zotsatira:
Cummings DE, Ng'ombe DS, Frayo RS, Breen PA, et al. Mazira a Plasma ghrelin pambuyo pa kudya-amachititsa kulemera kwa thupi kapena chapamimba chochita opaleshoni. N Engl J Med 2002; 346: 1623-1630.
Klok MD, Jakobsdottir S, Drent ML. Udindo wa leptin ndi ghrelin mu lamulo la kudya ndi kulemera kwa thupi mwa anthu: ndemanga. Obes Rev 2007; 8: 21-34.
Tschop M, Smiley DL, ML Heiman. Ghrelin amachititsa kuti mukhale ndi makoswe. Chilengedwe 2000; 407: 908-913.
Mozaffarian D, Hao T, Rimm EB, Willett WC, et al. Kusintha kwa zakudya ndi moyo ndi kupindula kwa nthawi yaitali kwa amayi ndi abambo. N Engl J Med 2011; 364: 2392-2404.