Funso: Kodi Muyenera Kutenga CoQ10 ndi Statins?
Dokotala wanga andiika ine pa generic simvastatin kuti ndichepetse cholesterol wanga. Ndikuwoneka ndikulekerera, koma ndamva kuti ngati mutenga mankhwala osokoneza bongo, muyenera kutenga CoQ10 kuti muteteze mavuto a minofu. Kodi izi ndi zoona? Kodi ndiyenera kutenga CoQ10?
Yankho: Tsoka ilo, palibe yankho lolondola la funso ili.
Komabe, umboni wa chipatala womwe tikuyenera kukhala nawo umasonyeza kuti CoQ10 sichithandiza kwambiri, makamaka, kuteteza kapena kusamalira mavuto a minofu ndi statins .
Kodi CoQ10 N'chiyani?
CoQ10 - amadziwikanso monga ubiquinone - ndi coenzyme yomwe imathandiza minofu kupanga mphamvu zomwe akufunikira kuti azigwira ntchito yawo. Ngakhale kuti kafukufuku wina wasonyeza kuti zilembo zingachepetse kuchuluka kwa CoQ10 mu minofu ya minofu, maphunziro ena sanapeze kuchepa kwa magulu a CoQ10 ndi statins. Choncho ngakhale funso loti ngati statins limakhudza coQ10 mndandanda konse sizowonekera bwino. Mulimonsemo, ambiri amalingalira kuti maola ochepa a CoQ10 angapangitse myopathy (kuvulala kwa minofu) yomwe ingachitike ndi statins . Kotero, madokotala ena amalimbikitsa CoQ10 kuwonjezera ndi mankhwala a statin.
Kodi Umboni Pa CoQ10 ndi Statins?
Buku lachipatala limasakanizidwa pa funso la CoQ10, ndipo pazifukwa ziwiri.
Choyamba, monga momwe tafotokozera, sikuti maphunziro onse amasonyeza kuti zilembo zimakhudza miyeso ya CoQ10 mu minofu yokha.
Ndipo chachiwiri, maphunziro ndi CoQ10 mwa anthu omwe amatenga zilembo akhala ochepa. Zochepa, zochepa, maphunziro afupikitsa zatha, ndipo zotsatira za maphunziro ochepawa akhala akukhumudwitsa.
Maphunziro a zachipatala omwe apita pano awona momwe CoQ10 ingathandizire kupweteka kwa misinkhu.
Cholinga cha maphunzirowa chinali kudziwa ngati kutenga COQ10 kungalole kuti odwala ali ndi kupweteka kwa minofu kuti apitirize kutenga zilembo. Ichi ndi nkhani yofunika, chifukwa pokhudzana ndi kuchepetsa chiwopsezo cha mtima chifukwa cha mitsempha ya kolesterolini, sipanakhale cholowetsa m'malo mwa statins .
Maphunzirowa apangitsa zotsatira zotsutsana. Kuyesedwa kwapadera kwa odwala 32 omwe ali ndi ululu wopweteka m'mimba kumasonyeza kuti, pambuyo pa masiku 30, omwe amalandira CoQ10 anali ndi kuchepa kwakukulu kwa kupweteka kwa minofu poyerekeza ndi zomwe zinavuta kuti alandire vitamini E. Kutalika kwa masiku 30 a phunziroli kumaonedwa vuto, komabe, chifukwa zimatenga masiku oposa 30 kuti CoQ10 supplementation kukhudza kuchuluka kwa CoQ10 mu minofu okha. Kuwonjezera apo, mayesero ochuluka, omwe akhalapo nthawi yayitali ndi CoQ10 sanasonyeze kusintha kwa kupwetekedwa kwa minofu pazithunzi.
Pofuna kuthetsa vutoli, kufotokozera meta kunachitika mu 2015, kufufuza mayesero omwe alipo. Kufufuza uku sikupeza phindu lalikulu pamene CoQ10 imagwiritsidwa ntchito pochiza myopathy. Komabe, ubwino wa maphunziro omwe alipo ulibe vuto, kotero zotsatira za kuyang'ana metazi sizingaganizidwe kukhala zomveka.
Mayesero akuluakulu a nthawi yayitali angakhale ofunikira kupeza yankho pafunso ili.
Palibe ichi, komabe, chimayamba kufunsa funso lanu, ndiko kuti, kodi munthu amene amatenga ma statins ayenera kutenga CoQ10 kuti ateteze statin myopathy? Chifukwa chomwe ndangotchulapo za kugwiritsa ntchito CoQ10 kuti muzitha kupweteka kwa mitsempha yapamwamba ndikuti pali deta yomwe ilipo yomwe imayankha funso ili (mofanana ndi deta).
Koma pankhani ya kugwiritsira ntchito CoQ10 ngati njira yowonetsera, umboni wokhawo ulipo wosagwirizana. Palibe zowonongeka zowonongeka zomwe zimayankha funso ili.
CoQ10 ndi Statins - Mfundo Yofunika Kwambiri
Mfundo yaikulu ndi yakuti palibe umboni wabwino, wofunikira kuchokera ku mayesero a kachipatala omwe alipo kuti awone ngati CoQ10 imalepheretsa kapena kuchitapo kanthu kupweteka kwa minofu. Panthawi imodzimodziyo, chiphunzitso chomwe CoQ10 chingathandize chingakhale chokondweretsa, ndipo maphunziro omwe achitika ndi ochepa m'kukhala kwawo ndi nthawi yake. Komanso, kutenga CoQ10 zowonjezereka (monga momwe akudziwira aliyense) ndi zopanda pake.
Kotero ngati muli ndi chidwi poyesera, ndipo mukhoza kuchipeza, madokotala ambiri sakanenapo kutsutsa kwakukulu pa lingaliro.
Ngati mukumva ululu wa minofu mukakhala pazithunzi, muyenera kulankhula ndi dokotala wanu poyesa mankhwala osokoneza bongo omwe amadziwika kuti sangathe kubweretsa mavuto a minofu, omwe ndi Lescol (fluvastatin) kapena Pravachol (pravastatin). Komanso, onetsetsani kuti dokotala amayang'ana ntchito yanu ya chithokomiro ndi mavitamini anu a D vitamini D, popeza kuti hypothyroidism kapena vitamini D otsika amapanga statin myopathy moyenera.
> Zotsatira:
> Banach M, Serban C, Sahebkar A, et al. Zotsatira za Coenzyme Q10 pa Myopathy yogwidwa ndi Statin: Meta-analysis of Randomized Controlled Trials. Mayo Clinic 2015; 90:24.
> Bookstaver DA, Burkhalter NA, Hatzigeorgiou C. Zotsatira za Coenzyme Q10 Kuonjezera pa Myalgias yomwe inachititsa kuti tizilombo toyambitsa matenda tiyambe. Am J Cardiol 2012; 110: 526.
> Caso G, Kelly P, McNurlan MA, Lawson WE. Zotsatira za Coenzyme q10 pa Zizindikiro za Myopathic kwa Odwala ochiritsidwa ndi Statins. Am J Cardiol 2007; 99: 1409.
> Taylor BA, Lorson L, White CM, Thompson PD. Kuyesedwa kosawerengeka kwa Coenzyme Q10 mwa Odwala omwe ali otsimikiziridwa ndi Statin Myopathy. Atherosclerosis 2015; 238: 329.