Kafukufuku akufufuza kugwirizana komwe kulipo pakati pa ululu wa celiac, kutsekemera kwa gluten ndi kuvutika maganizo
Ngakhale kuti anthu ambiri amaganiza kuti matendawa ndi amtundu winawake omwe amapezeka makamaka m'thupi lawo, kafukufuku amasonyeza kuti zinthuzi zimakhala ndi zotsatira zambiri m'thupi lanu, kuphatikizapo pamagulu anu, mahomoni anu, komanso ubongo wanu.
Chifukwa cha zimenezi, kodi angapereke chithandizo ku-kapena matenda - Alzheimer's and dementia ?
Mwamwayi, zikuwoneka kuti sizikuwoneka: umboni wochokera ku maphunziro a zachipatala mpaka pano unena kuti kusungunuka kwa gluten sikungakupangitse chiopsezo cha matenda a dementia kapena matenda a Alzheimer ngati muli ndi matenda a celiac kapena mphamvu ya gluten.
Matenda a Celiac ndi Matenda a Alzheimer: Kodi Umboni ndi Chiyani?
Dr. Alessio Fasano, yemwe ndi mkulu wa chipatala cha Massachusetts General Hospital (Research Celiac Research and Treatment), akunena kuti kufufuza kwaposachedwa kumeneku, komwe kunachitika ku Sweden, kumasonyeza kuti kukhala ndi matenda a celiac sikuwonjezera chiopsezo cha matenda a maganizo ndi matenda a Alzheimer.
Kafukufukuyu anawona anthu 8,846 a zaka zapakati pa 50 ndi kupitirira omwe anapezeka kuti ali ndi matenda a celiac pogwiritsira ntchito matumbo a m'mimba kuti atsimikizire kuwonongeka kwa m'mimba, ndipo anawayerekezera ndi anthu 43,474 omwe alibe matendawa. M'badwo wapakati wamaphunziro a phunziro anali wazaka 63.
Pazaka zoposa zisanu ndi zitatu zotsatila, matenda a dementia anapezeka mu 4,3 peresenti ya anthu omwe ali ndi matenda a celiac ndipo 4,4 peresenti ya gulu lolamulira.
"Tikulimbikitsanso kuti sitinapezeko ngozi yaikulu," analemba motero.
Kafukufukuyu adawonetsa kuti chiwopsezo cha matenda a chiwopsezo cha mthupi chakawonjezeka m'chaka choyamba chitatha matenda a celiac. Komabe, chiopsezo chimenechi sichinapitirire chaka choyamba, ndipo olemba a maphunzirowo adanena kuti mwina chifukwa chakuti anthu omwe ali mu phunziroli adayesedwa mosamala, ndipo matenda omwe adakalipo kale koma anali asanawonepo anali ambiri Momwemo angapezedwe ndi kuchiritsidwa chifukwa cha izi.
Vuto la Vascular Dementia Mwinamwake Anakulira
Zambiri zokhudzana ndi phunziroli, zomwe adazipeza zakhala zikuwopsa kwambiri za matenda a dementia-mtundu wa chiwopsezo cha umutu chifukwa cha kuchepa kwa magazi ku ubongo wanu-pakati pa anthu omwe ali ndi matenda a celiac. Izi zikhoza kukhala zovuta, olembawo analemba, chifukwa anthu omwe ali ndi matenda a celiac amakhala ndi chiopsezo chochepa cha matenda a mtima, omwe amachititsa kuti mukhale ndi matenda a maganizo.
N'zotheka kuti chiopsezo chotere cha matenda a dementia chikhoza kukhala chifukwa cha kuchepa kwa vitamini- mwakuya, kusowa kwa vitamini B12, omwe olemba analemba. Komabe, kufufuza kwina kudzafunika kuti mudziwe ngati izi ndi zoona.
"Kupeza kuti chiwopsezo chachikulu cha matenda a dementia (osati matenda a Alzheimer's 'dementia') kungakhale chifukwa cha ngozi koma kumachititsa kuti vuto la dementia likhoza kukhala zotsatira za nthawi yaitali za matenda a leliac ofanana ndi chiopsezo chokhazikika cha mtima ndi matenda a cerebrovascular disease , "analemba motero.
Kafukufuku Wowonjezereka Mwinamwake pa Alzheimer's and Celiac
Ngakhale kuti maphunziro ochokera ku Sweden ndi umboni wamphamvu wakuti matenda a leliac saika chiopsezo chanu cha matenda a dementia ndi matenda a Alzheimer, mwina sichidzakhala mawu otsiriza pa nkhaniyo. Kafukufuku wina wakale akuti kugwidwa kwa gluten kungakhale koipitsa kapena ngakhale kumayambitsa matenda a Alzheimer ndi mitundu ina ya matenda a dementia kwa anthu omwe ali ndi matendawa.
Dr. Fasano akuti akuyembekeza kufufuza kwina kuti apitirize kufufuza nkhaniyi: "Kuti mudziwe ngati pali mgwirizano uliwonse pakati pa matenda a leliac ndi matenda a Alzheimer's late-morning, timafunikira maphunziro omwe akutsatira anthuwa kwa nthawi yaitali. , tikhoza kudziwa momwe matenda a chililiac amakhudzira chitukuko cha matenda a Alzheimers kapena mitundu ina ya dementia ndi kuchepa kwa chidziwitso. "
Kafukufuku wina anapeza kuti magulu a majeremusi okhudzana ndi matenda a leliac ndi matenda ena , kuphatikizapo matenda a nyamakazi ndi matenda opatsirana, amakhalanso ndi matenda a Alzheimer's.
Zomwe zimachitika zikuwonekera kukhala kutupa, olemba a phunziroli analemba. Koma kachiwiri, kafufuzidwe kafukufuku amafunika pa ma jini ndi zotsatira zake kuti asokoneze mgwirizano uliwonse.
Palibe Umboni Wotsutsa mu Njere Ubongo
Mwinamwake mumadziŵa katswiri wamagulu a ubongo Dr. David Perlmutter, wolemba za Grain Brain, amene amatsutsa mapuloteni a gluten m'magulu a tirigu, balere, ndi rye (ndipo pamtunda winawake, mbewu zonse) pofuna kuchepetsa thanzi la ubongo kuti nthawi zina kumayambitsa matenda a maganizo. Mankhwala ake ayenera kupewa carbs-based carbs, makamaka gluten.
Dr. Perlmutter's Grain Brain akuchenjeza kuti tirigu (ndi mbewu zina) ndizoyipa kwa ubongo waumoyo kwa aliyense, osati okhawo omwe ali ndi matenda a leliac kapena kutsekemera kosaleta kakomedwe. Amaimba mlandu wokhudzana ndi shuga wamagazi wokhudzana ndi tirigu, kunena kuti izi zimayambitsa matenda a shuga ndi matenda a shuga, shuga, ndipo pamapeto pake nzeru zimachepa komanso zimabwerera m'mbuyo.
Vuto ndilo, mfundo za Dr. Permutter zimatsatiridwa makamaka ndi umboni wake weniweni, ndipo sizimamangiriridwa ndi maphunziro apamwamba azachipatala. Palibe umboni wa sayansi wosonyeza kuti gluten ndi / kapena mbewu zingayambitse matenda a Alzheimer kapena mitundu ina ya dementia.
Kutupa ndi Microbiome
Wasayansi wina yemwe akufufuza kuti mwina matenda a gluteni angapangitse munthu kukhala ndi maganizo ochititsa munthu kukhala ndi maganizo olakwika aumphawi ndi Dr. Mak Daulatzai, katswiri wa zamaganizo komanso a kafukufuku wamkulu wa zamankhwala ku yunivesite ya Melbourne ku Australia. Malinga ndi pepala la 2015 lolembedwa ndi Dr. Daulatzai, kusintha kwa m'matumbo anu a m'matumbo omwe amachititsidwa ndi mphamvu zowonongeka zazing'ono zingayambitse kutupa thupi lonse, zomwe zingayambitse chiopsezo chachikulu cha matenda a dementia ndi matenda a Alzheimer's.
Daulatzai akuuza kuti: "Matupi athu amalekerera zakudya zambiri ndipo sagwira ntchito yoteteza thupi. "Komabe, ngati matupi a anthu ena] amadziona kuti ndi amtundu wakuda," ndikuchitapo kanthu. Izi zimayambitsa kutupa, akuti, "akhoza kuwonetsa mawonetseredwe a maganizo / a maganizo ndi a mitsempha" a zowopsya, zomwe zingakhale kuphatikizapo matenda a maganizo.
Dokotala Daulatzai akuti njira iyi yothetsera umutu waumtima imakhalabe yongopeka komanso yosatsutsika, ngakhale iye akulemba kuti gulu lake likugwira ntchito pafukufuku omwe angabweretsere chiphunzitso chake.
Mfundo Yofunika Kwambiri
Umboni wamakono ukuwonetsa kuti kukhala ndi matenda oopsawa sikuwopsa chifukwa cha matenda a Alzheimer's or dementia. Pakalipano, palibe umboni wachipatala umene umasonyeza kuti munthu ali ndi mphamvu zokhudzana ndi ubongo zingayambitse chiopsezo chanu pazochitika ziwiri zomwe zimagwirizana ndi ubongo-ngakhale kuti kafukufuku wa Dr. Daulatzai wapanga njira yothetsera mgwirizano woterewu, sungakhale wosatsimikiziridwa ndi wowongolera.
Tsono ngakhale zakudya zopanda thanzi zili ndi phindu lodziwika bwino pa thanzi lanu ngati muli ndi matenda a celiac kapena kutengeka kwa gluten, mwatsoka simungathe kuwerengera kuti muteteze ku matenda a Alzheimer's or dementia. Mwamwayi, pali njira zina zomwe mungathandizire kuchepetsa chiopsezo cha Alzheimer's , kuphatikizapo zolimbitsa thupi (zonse zakuthupi ndi zamaganizo).
> Zotsatira:
> Daulatzai MA. Gulu lachilendo lopanda chidziwitso Chokhalitsa Kutentha kwa Dysbiosis, Neuroinflammation, Gut-Brain Axis Dysfunction, ndi Vulnerability for Dementia. Matenda a CNS & Neurological - Malangizo a Mankhwala. 2015; 14 (1): 110-31.
> Lebwohl B et al. Kuopsa kwa Dementia kwa Odwala Odwala Matenda Oopsya: Phunziro la Ogwirizanitsa Anthu. Journal of Disease's Alzheimer's. 2016; 49 (1): 179-85.
> McKeon A et al. Kufunika kwa Neurologic kwa Zizindikiro Zachilombo Zachilombo. Neurology. 2014 Nov 11; 83 (20): 1789-96.
Yokoyama JS et al. Kugwirizana Pakati pa Makhalidwe Achibadwa a Matenda Opatsirana Ndi Immune ndi Matenda a Alzheimer. JAMA Neurology . 2016 Jun 1; 73 (6): 691-7.