Matenda a Pick ndi Corticobasal Degeneration Amakhudza Circadian Rhyms
Kodi matenda a maganizo oterewa monga matenda a Pick ndi a corticobasal degeneration amakhudza bwanji kugona? Phunzirani za izi, kuphatikizapo zizindikiro zawo, komanso momwe dementia yomwe imakhudzira lobes ndipakati pa ubongo imakhudza kugona ndi zozungulira.
Kodi Dementia ya Frontotemporal Ndi Chiyani?
Dementia imaphatikizapo mavuto osiyanasiyana omwe amachititsa ubongo kupititsa patsogolo ndipo amatha kukumbukira, kusamala, umunthu, chinenero, kuthetsa mavuto, ndi ntchito tsiku ndi tsiku.
Pakati pa gulu lalikululi, pali zinthu zomwe zimakhudza mbali zina za ubongo ndipo zimayambitsa zovuta zina. Imodzi mwa mitundu yeniyeniyi ndi ya frontotemporal dementia (FTD), matenda omwe amakhudza lobes oyambirira ndi apakati a ubongo (omwe ali kutsogolo ndi kumunsi kwa ubongo). Zimakhudza anthu 5 mpaka 15 peresenti ya anthu omwe ali ndi matenda a maganizo.
Kugonjera kwaumphawi kwapakati pa nyengo kumaphatikizapo zikhalidwe ziwiri zosiyana: Matenda a Pick ndi a corticobasal degeneration. Zakale zimakhala ndi zovuta zapadera zomwe zimatchedwa Thupi, zomwe zimapezeka mkati mwa ubongo zomwe zimakhala ndi mtundu wambiri kapena mapuloteni otchedwa tau. Pali majeremusi omwe amawoneka kuti amachititsa kuti matendawa achitike, koma chifukwa chenichenicho sichikudziwika. Matenda a Pick ndi matenda omwe sapezeka omwe amapezeka nthawi zambiri kwa anthu omwe ali ndi zaka 40 mpaka 60.
Mosiyana ndi zimenezi, ma corticobasal degeneration (CBD) amadziwika ndi kuchepa kwa neurons mu cerebral cortex ndi basal ganglia, mbali ziwiri za ubongo zomwe zimayambitsa kuganiza ndi kuyenda.
Matendawa amatha kukhudza mbali imodzi ya thupi poyamba, koma ngati matendawa akupita, mbali zonse ziwiri za thupi zingakhale zogwirizana. CBD ikhoza kuyamba pafupifupi zaka 60.
Kodi Ndi Zizindikiro Ziti za Dementia ya Frontotemporal?
Mbali ya ubongo yomwe imakhudzidwa ndi matenda a demokarasi ya frontotemporal imabweretsa zizindikiro zina.
Ndi matenda a Pick, umunthu woyambirira komanso kusintha kwa khalidwe kungayambe. Izi zikhoza kuwonetsa ngati zovuta m'makhalidwe a anthu ndi zovuta, zovuta, kapena zosayenera. Mosiyana ndi matendawa , matenda a Alzheimer amadziwika ndi kutaya mtima ngati chizindikiro chachikulu. Anthu omwe ali ndi matenda a Pick akhoza kukhala osasinthasintha kapena amaoneka osasamala (osamvetsetsa), ndipo pangakhale mavuto okhudzana ndi kulankhula (otchedwa aphasia) ndi maganizo olakwika. M'kupita kwanthawi, kufooka kapena kuzindikiritsa kungakhalepo. Monga lamulo, zizindikiro izi zidzapitirira pang'onopang'ono.
Kuchulukana kwa Corticobasal kuli ndi zizindikiro zina chifukwa cha zotsatira za basal ganglia. Izi zikhoza kuwonetsa zizindikiro zofanana ndi matenda a Parkinson, kuphatikizapo kuuma, kuchepa, ndi kusamvana. Anthu omwe ali ndi CBD adzakhalanso ndi apraxia, omwe sangakwanitse kuyenda mosamala ngakhale kuti mphamvu ndi kugwirizana kulipo. Mwachitsanzo, wina yemwe ali ndi CBD sangathe kufanana ndi kusuntha mano, kusuta fodya, kusakaniza tsitsi, kapena kudya supu kuchokera ku supuni. Mavuto amenewa amachititsa kuti zisakhale zovuta kuyenda. Kulankhulana kungachepetse, ndipo kuvutika kukumeza kungathenso kuchitika.
Frontotemporal Dementia ndi Zotsatira za Kugona
Kugona kwa anthu okhala ndi dementia ya frontotemporal kungasinthe, ndipo kwenikweni, chitsanzo cha kugona ndi kudzuka chimasintha.
Chizoloŵezi chachibadwa cha circadian chimakhala chogawidwa kwambiri, ndi chisakanizo cha ziwirizi zikuchitika masana ndi usiku. Izi zikuwoneka kuti zikungosintha zopitirira zomwe zingatheke pamene mukukhala kumalo osungirako othandizira ngati nyumba yosungirako okalamba. Anthu okhudzidwa amakhala ndi nthawi yayitali yakugona, akugona ndi kuuka kuposa kale.
Mukaona ndi electroencephalogram (EEG) , chiŵerengero cha maubongo a ubongo si chachilendo: ndi pang'onopang'ono panthawi ya kuuka. Komabe, zikhoza kukhala zachilendo kwa munthu mmodzi mwa atatu, choncho sizowona bwino kuti muzindikire.
Matenda ena ogona angayambe kutsogolo kwa demokrasi ya frontotemporal chifukwa chimodzimodzi chomwe chimachitika pakati pa anthu onse, kuphatikizapo kugona tulo .
Izi zingafunikire kufufuza ndi njira yoyenera yothandizira, malingana ndi kuwonongeka kwakukulu kwa chifuwa cha maganizo.
Kuchiza ndi Kugonjetsa mu Frontotemporal Dementia
Palibe mankhwala omwe amatha kuchepetsa kapena kusintha njira ya dementias. Mankhwalawa, kuphatikizapo kugwiritsa ntchito mankhwala, akhoza kuthandizira kuchepetsa zizindikiro zinazake, koma mwatsoka, izi zikhoza kukhala zosagwira ntchito. Chithandizo choyenera ndi chofunikira, kuphatikizapo kupereka malo abwino ndi thandizo lofunikira.
Zotsatira za kutsogolo kwa demokarasi yapopotemporal nthawi zambiri imakhala yosauka, ndi njira yomwe ikukula ndi kuipira - komanso kulemala ndi kachilombo kawirikawiri. Matenda a Pick amatsogolera ku imfa mkati mwa zaka ziwiri mpaka 10, makamaka kuchokera ku matenda (monga chibayo kapena matenda a umtsinje), kapena vuto lina la vuto lalikulu. Kuwonongeka kwa Corticobasal kumatsatira nthawi yomweyo, kumapitirira zaka 6 mpaka 8 ndikupititsa ku imfa m'njira zofanana.
Ndikofunika kuti osowa ndi okondedwa a anthu omwe ali ndi dementia ya frontotemporal akhale ndi chithandizo chothandizira ndikupeza mpumulo ngati pakufunikira. Kusokonezeka tulo kungakhale kagawo kakang'ono pambali pa zovuta zina, koma kusokonezeka kwa machitidwe ogona kumabweretsa mavuto kwa munthu wokhudzidwayo ndi omwe akusamalira. Choncho kusamalira kugona tulo kungapindule ndi kuchitapo kanthu ndikuthandizani kuchepetsa nkhawa.
Ngati mukupeza kuti mukusowa thandizo lothandizira kuthetsa vutoli, mungapindule ndi kufunsa ndi katswiri wa zamaganizo, omwe angathandize kuthandizira chisamaliro ndi kupereka zolembera kuzinthu zamdera lanu.
Zotsatira
Kryger, MH et al . "Mfundo Zothandiza Pogona Mankhwala." Elsevier , edition lachisanu, p. 1042.
"Sankhani matenda." Zolemba Zaumoyo Zapezeka: January 30, 2013.
"NINDS Corticobasal Degeneration Information Page." National Institute of Neurological Disorders ndi Stroke . Zapezeka: January 30, 2013.