West Syndrome

West Syndrome ndi Infantile Spasms

Matenda a West ndi mtundu wodwala matenda opatsirana (kutupa kwa khunyu) komwe kumayambira ali wakhanda. Mtundu wapadera wa kulanda wotchedwa infantile spasm ndi gawo la matendawa, monga momwe amachitira zovuta za ubongo zotchedwa hypsarrhythmia, ndi kuchepetsa maganizo. Pafupifupi vuto lililonse limene lingayambitse ubongo lingayambitse matenda a West. Zomwe zimayambitsa matendawa ndi tuberous sclerosis komanso kusowa kwa oxygen panthawi yobadwa.

Nthawi zina zifukwa zimakayikira koma sizingatsimikizidwe; Pankhaniyi, imatchedwa cryptogenic West syndrome.

Matenda a West amachititsa 2 peresenti ya khunyu ali mwana, koma 25 peresenti ya khunyu yomwe imayamba m'chaka choyamba cha moyo. Kuchuluka kwake kwa kuperewera kwa ana kumayerekezera pakati pa 2.5 ndi 6.0 pa kubadwa kwa anthu 10,000.

Zizindikiro za West Syndrome

Matenda a West amayamba kawirikawiri pakati pa zaka 3 ndi 6 miyezi.Symptoms ndi:

• Mafupa a anyamata - Nthawi zambiri pamtambo wotere mwanayo amadzidzimutsa pachiuno ndipo thupi, mikono, ndi miyendo zimafooka. Izi nthawi zina zimatchedwa "jackknife". Achinyamata ena amatha kugwedeza misana yawo, kapena kupukuta mitu yawo, kapena kuwoloka manja awo mthupi lonse ngati akudzikumbatira okha. Maseŵera awa amatha masekondi angapo ndipo amapezeka m'magulu apakati pa 2 mpaka 100 mazenera pa nthawi. Ana ena ali ndi masango ochulukirapo ambiri pa tsiku. Mafasimu amapezeka nthawi zambiri mwana akadzuka mmawa kapena atagona.

• Hypsarrhythmia - Electroencephalogram (EEG) imalemba ntchito zamagetsi mu ubongo monga mawonekedwe a ubongo. Mwana wakhanda amene ali ndi matenda a West adzakhala ndi zovuta zowopsya za ubongo zotchedwa hypsarrhythmia.
• Kutaya kwa mtima - ndiko chifukwa cha kuvulala kwa ubongo komwe kwachititsa kuti matenda a West syndrome.

Zizindikiro zina zikhoza kukhalapo chifukwa cha matenda omwe amachititsa matenda a West.

Matenda ena a ubongo monga cerebral palsy angakhaleponso.

Kuzindikira West Syndrome

Matenda a West adzatchulidwa ndi kupezeka kwa malo osokoneza bongo. Kufufuza koyenera kwa kagawo kudzachitika pofuna kuyang'ana zifukwa zomwe zingayambitse. Izi zingaphatikizepo mayesero a ma laboratori ndi kupima ubongo pogwiritsa ntchito computed tomography (CT) kapena kujambula kwa magnetic resonance (MRI). EEG idzachitidwa pofuna kuyang'ana hypsarrhythmia kawirikawiri akupezeka ku West syndrome.

Kuchiza kwa West Syndrome

Nthawi zambiri matenda a West West amachiritsidwa ndi adrenocorticotropic hormone (ACTH) kapena prednisone. Mankhwalawa angakhale othandiza kwambiri poletsa kapena kuchepetsanso mpweya wabwino. Ana ena angayankhe mankhwala osokoneza bongo monga Felbatol (felbamate), Lamictal (lamotrigine), Topamax (topiramate), kapena Depakote (valproic acid). Ana omwe ali ndi tuberous sclerosis akhoza kuchiritsidwa ndi vigabatrin (osati panopa yovomerezeka kugwiritsidwa ntchito ku US). Nthawi zina, kuchotsa minofu ya ubongo yowonongeka kupyolera mu opaleshoni ya ubongo ikhoza kukhala yothandiza.

Mafilimu a ana aamuna nthawi zambiri amatha kuthetsa pafupifupi zaka zisanu, koma oposa theka la ana omwe akukhudzidwa amakhala ndi matenda ena, kuphatikizapo matenda a Lennox-Gastaut. Ana ambiri omwe ali ndi matenda a West West amakhala ndi chidziwitso cha nthawi yaitali komanso kuphunzira, chifukwa cha kuwonongeka kwa ubongo komwe kunayambitsa matenda a infantile.

> Zotsatira:

_{"NINDS Information Spasms Information Page." Kusokonezeka AZ. 9 Dec 2008. National Institute of Neurological Disorders ndi Stroke.}

_{"Childhood Spasms / West Syndrome." Syndromes a khunyu. Epilepsy Foundation.}