Kodi pali kugwirizana pakati pa khansa ya estrogen ndi mapapo? Tikudziwa kuti pali kusiyana kwakukulu pakati pa khansa yamapapu mu khansa ya amayi ndi khansa m'mabambo. Timadziwanso kuti maselo a khansa yamapapo ali ndi maselo a estrogen, ndiko kuti, malo omwe ali pamwamba pa selo omwe angathe kumanga ndi estrogen. Ngakhale kuti chidziwitso chathu sichingatheke panthawiyi, izi zikutanthawuza chiyani kwa amayi omwe ali ndi kansa ya m'mapapo lero, kapena pangozi ya kansa ya m'mapapo m'tsogolomu?
Musanalankhule za maphunziro, ndibwino kufotokoza chifukwa chake zotsatira zina zingakhale zosokoneza. Pali njira zosiyanasiyana (njira) zomwe estrogen imakhala nayo mu kansa ya m'mapapo. Ndifunikanso kusonyeza kuti maphunziro ambiriwa akukamba za nkhani ziwiri zosiyana kwambiri. Choyamba ndi kuyambitsa-mwina msinkhu wapamwamba kapena wotsika wa estrogen umakhudza ngati wina angayambe khansa ya m'mapapo poyamba? Zina ndizopitirira-kodi estrogen imayambitsa khansara yamapapu imene yayamba kale kukula msanga kapena pang'onopang'ono?
Mbiri Yobereka
Ngakhale timadziwa kuti khansa ya m'mawere imakhala yowonongeka kwambiri kwa amayi omwe amayamba kukhala ndi nthawi msinkhu, maphunziro sapeza kuti ndizovuta ndi khansa ya m'mapapo. Matenda a khansa amawoneka kuti ndi ochepa kwambiri kwa amayi omwe ali ndi ana ambiri kuposa omwe ali ndi ana ochepa kapena osakhala nawo konse, makamaka amayi amene sanasute fodya.
Kusanthula kwaposachedwapa kwa maphunziro mpaka lero kumasonyeza kuti khansara yochepa ya sepulo yamapapu , koma osati khansa yaing'ono yamapapu yamapapu , ingakhale yochepa kwambiri mwa amayi omwe ali ndi ana ambiri. Kafukufuku wina anapeza kuti, mosiyana ndi khansa ya m'mawere, vuto la khansa yamapapu linali lochepa kwambiri pamene akazi anabala panthawi ina.
(Poyerekezera, ndi khansa ya m'mawere chiwopsezo chachepetsedwa pokhala ndi mwana woyamba kumayambiriro kwa moyo (asanakwane 30) koma chiopsezo cha khansa ya m'mapapo kachepetsedwa pang'ono pokhala ndi mwana m'tsogolo.)
Kafukufuku waposachedwapa akusonyeza kuti amayi omwe ali ndi mazira awo onse (kuchotsa kusamba kwa mimba) akhoza kukhala ndi chiopsezo chokwanira chokhala ndi khansa ya m'mapapo. Kafukufuku wina awonetsanso mgwirizano wochepa pakati pa kusamba kwa nthawi yoyamba ndi chitukuko cha khansa ya m'mapapo.
Zinyama
Kafukufuku wina pa mbewa adanena kuti estrogen ingalimbikitse kukula kwa khansa ya m'mapapo. Mu phunziroli, mbewa zazimayi zomwe zinali ndi mazira ambiri zimapanga mapiko ambiri a mapapo kusiyana ndi mbewa zazimayi zimene zinachotsedwa. Kuwonjezera apo, pamene mbewa zopanda mazira zinkasamalidwa ndi estrogen, zotupa zawo zimakula mofulumira kuposa mbewa zomwe sizinachitike ndi estrogen.
Mankhwala Othandizira Amadzimadzi Otchedwa Hormone
Kachilombo kamene kamayambitsa mankhwala , kapena HRT (estrogen ndi progesterone) chifukwa cha matenda a mimba amatha kupha ngozi ya khansa ya m'mapapo, makamaka anthu omwe amasuta. Pofufuza azimayi 16,000 omwe ali ndi kansa ya m'mapapo yopanda maselo, omwe amagwiritsa ntchito mankhwala osakanikirana a hormone anali oposa 60 peresenti yakufa ndi matendawa. Ndikofunika kuzindikira kuti mu phunziro lino, kuphatikiza HRT kunayambitsa chiopsezo cha imfa kuchokera ku khansara yamapapo ngati kale anali nayo, koma osati mwayi woti winawake angayambe khansa ya m'mapapo.
Kawirikawiri, kufufuza kuyang'ana zofanana monga chifukwa cha khansa ya m'mapapo kwasakanikirana, ena akuwonetsa kuwonjezeka, kusonyeza kusonkhana, ndi maphunziro ena atsopano omwe akuwonetsa kuchepa kwa chiopsezo cha khansa yamapapu.
Kupenda kwa PLoS posachedwa kunayang'ana ntchito ya estrogen mankhwala (popanda progesterone) yokha pangozi ya khansa ya m'mapapo mwa amayi ngati gawo la kufufuza kwa California Teachers. Mu phunziro ili, panalibe mgwirizano (palibe kuwonjezeka kapena kuchepa) pakati pa kugwiritsa ntchito mankhwala othandizira (estrogen ndi progesterone) ndi chiopsezo cha khansa ya m'mapapo. Komabe, kwa amayi omwe amagwiritsira ntchito mankhwala a estrogen okha, ogwiritsira ntchito kale a estrogen ndi nthawi yochepa yogwiritsira ntchito (osakwana zaka zisanu) anali ndi chiopsezo chochepa chofa ndi khansara yamapapo (46 peresenti yochepa), ndi ogwiritsa ntchito posachedwapa a estrogen ndi yaitali Kutalika kwa ntchito (zaka zoposa 15) kunakhalanso ndi chiopsezo chochepa chakumwalira (40 peresenti yochepa).
Kafukufuku wina anapeza khansa ya m'mapapo ya m'mimba mwa amayi omwe adagwiritsa ntchito mapiritsi a pakamwa.
Phytoestrogens
Kudya kwa estrogens (phytoestrogens) ya zomera (monga phytoestrogens), monga yomwe imapezeka mu soya, yakhala ikuyang'aniridwa mu kafukufuku wowerengeka ndi khansara yamapapo. Zina mwa izi, zimawoneka kuti amayi omwe amadya zakudya zamtundu wa phytoestrogens ali ndi chiwerengero chochepa cha khansa ya m'mapapo, makamaka mwa amayi omwe sanasute fodya.
Pansi
Popeza khansara yamapapo ndi, mwa njira zambiri, matenda osiyana azimayi, nkofunika kuyang'anitsitsa ntchito yeniyeni ya estrogen. Koma monga tanenera kale, zomwe tidziwa za khansa ya estrogen ndi mapapu imakali pachiyambi.
Ndi njira iliyonse kapena mankhwala, ndikofunikira kwambiri kufufuza ubwino wa mankhwala motsutsana ndi zoopsa zomwe zingatheke. Mwachitsanzo, ngati dokotala akukulimbikitsani kuti mavoesiti achotsedwe pazifukwa zina, kupindula kwa njirayi kungapitirire kuwonjezeka kwa chiopsezo cha khansa yamapapo.
Pakalipano, maphunzirowa ndi chikumbutso chabwino polankhula ndi dokotala ngati muli ndi mankhwala othandizira, makamaka ngati mumasuta, ndikufunsa mafunso. Kodi mukuyenera kumwa mankhwalawa? Kodi pali njira zina? Kodi pali zopindulitsa zomwe zimapitirira kupyola pangozi yapamwamba ya kufa kwa khansa ya m'mapapo (kapena kansa ya m'mawere)?
Pamapeto pake, kumvetsetsa kuti maselo a khansa yamapapo ali ndi maselo a estrogen amatsegula zitseko kuti mwinamwake mankhwala ena omwe amagwiritsidwa ntchito kaamba ka khansa ya m'mawere angathandize pa matenda a kansa yamapapo m'tsogolomu.
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