Teyi yaukhondo (Camellia sinensis) ikhoza kukhala ndi ubwino wa thanzi womwe umaphatikizapo kuteteza nyamakazi. Zotsatira zaphunziro zinalembedwa mu Proceedings of the National Academy of Sciences (1999) ndizo zoyamba kusonyeza kuti mankhwala ophera antioxidants omwe amapezeka mu tiyi wobiriwira, otchedwa polyphenols, akhoza kuchepetsa kuchepa kwa chifuwa chachikulu cha nyamakazi .
Nkhalango Yowonjezera Nkhanza Mu Maphunziro Oyamba
Phunzirolo, lotsogoleredwa ndi Dr. Tariq Haqqi wa University of Case Western Reserve ku Cleveland, Ohio, adagwiritsa ntchito mbewa kuti aphunzire zotsatira za mafupa a nyamakazi, nyamakazi, matenda, kutupa, ndi chiwonongeko.
Nthanga zomwe zili mu phunziroli zinapatsidwa madzi ozizira kapena madzi omwe amathiridwa ndi tiyi wobiriwira. Mlingo womwe wapatsidwa unkafanana ndi kumwa makapu anayi a tiyi patsiku. Nthawi zonse mbewazo zinkajambulidwa ndi collagen pofuna kuchepetsa nyamakazi. Matenda a kamolajeni amaonedwa kuti ndi ofanana kwambiri ndi nyamakazi ya nyamakazi.
Zotsatira za kafukufukuyo zinatsimikizira kuti mbewa zomwe zidadyetsedwa ndi tiyi ya tiyi ya polythhenols sizinali zovuta kuti tizipanga nyamakazi ya collagen kusiyana ndi mbewa zomwe sizidyetsa green tea polyphenols. Mwa mbewa idadyetsa tiyi wobiriwira omwe adayamba nyamakazi, idali ngati kumayambiriro koyamba ndi kofatsa. Mankhwala 8 okha mwa 18 alionse omwe amalandira tiyi yobiriwira amapangidwa ndi nyamakazi, pamene mapiritsi 17 mwa 18 osalandira green tea polyphenols anayamba nyamakazi.
Kufufuza kwa minofu yodziphatikizirayi imasonyeza kuwala kwapakati pa maselo ophatikizana m'magulu omwe amalandira tiyi wobiriwira mosiyana ndi kulowa mkati mwa mbewa zomwe sizinadyetse tiyi wobiriwira.
Zotsatira za tiyi wobiriwira zinawoneka zodabwitsa.
M'mayiko ambiri monga India, China, ndi Japan, tiyi wobiriwira amawonekeratu kuti ali ndi thanzi lothandizira kupewa matenda ena. Zikuwoneka kuti nyamakazi ya nyamakazi m'mayikowa ilipo pamtunda wotsika kwambiri kuposa kwina kulikonse padziko lapansi ndipo anthu ena amakhulupirira kwambiri chifukwa cha tiyi wobiriwira.
EGCG (Epigallocatechin 3-gallate) ndi polyphenol mu tiyi wobiriwira omwe amawoneka kuti ndiwophatikizapo. Malingana ndi lipoti la Arthritis Research & Therapy (2010), EGCG imakhala makatekini okwanira 63%. Pogwiritsa ntchito antioxidant ntchito, EGCG ndi 25 mpaka 100% yochulukirapo kuposa vitamini C kapena vitamini E. Chikho chimodzi cha tiyi wobiriwira chimapereka makatekini 60 mpaka 125 mg (kuphatikizapo EGCG).
Zotsatira za EGCG pa Synovial Fibroblasts
Zaka zonsezi zapitazo, zotsatira za thanzi la tiyi wobiriwira zinagwiridwa ndi ochita kafukufuku m'malo mofulumira. In vitro (ie, mu labotale) maphunziro ankachitidwa. Mu 2007, pafupifupi zaka zisanu ndi zitatu pambuyo pa phunziro loyamba, tiyi wobiriwira akukambanso nkhani. Panthawiyi, ofufuza a pa yunivesite ya Michigan adapeza kuti mankhwalawa ali ndi tiyi wobiriwira angathandize kupewa kutupa komanso kuwonongeka kwa chigwiridwe cha odwala nyamakazi.
Phunziro ili, synovial fibroblasts (maselo a mgonero) anali olekanitsidwa ndipo amakula. Maselowo anadziwika kwa EGCG. Zinatsimikiziridwa kuti EGCG inatseka ma molekyulu awiri omwe amagwirizana ndi kupunduka kwa mafupa omwe amakhudzidwa ndi nyamakazi ya nyamakazi. EGCG inaletsanso prostaglandin E2 yomwe imatulutsidwa ndi makoma a mitsempha ya magazi chifukwa cha matenda kapena kutupa.
Prostaglandin E2 imagwirizanitsidwa ndi kutukumula kotseguka.
Mayankho a EGCG
Kugwira ntchito kwa EGCG mu matenda a nyamakazi kapena nyamakazi ya osteoarthritis pogwiritsa ntchito mayesero olamuliridwa ndi gawo sikuyenera kuchitidwa. Ngakhale kuti maphunziro omwe alipo mu vitro asonyeza umboni wotsutsana ndi zovuta za EGCG, maphunziro oyenera kwambiri ndi ofunikira ndipo pamapeto pake, mayesero okhudza odwala omwe ali ndi matendawa.
Zotsatira:
Kupititsa patsogolo kwa National Academy of Sciences, 1999; 96: 4524-4529
Teyi yobiriwira imapezeka pofuna kuchepetsa kutupa, kupweteka kwa nyamakazi. NaturalNews.com. David Gutierrez. December 31, 2007.
Gulu lopaka ma pulophenol epigallocatechin 3-gallate mu nyamakazi: patsogolo ndi lonjezo. Salahuddin Ahmed. Arthritis Research and Therapy. April 2010.