Zizindikiro, Kuzindikira ndi Chithandizo cha Pheochromocytoma
A pheochromocytoma ndi mtundu wa chotupa chomwe chimapezeka m'matenda a adrenal kapena maselo ena ammitsempha. Ziphuphuzi ndizosowa kwambiri koma zimayambitsa zizindikiro zodabwitsa chifukwa zimakonda kutulutsa mahomoni ambiri otchedwa catecholamines . Ngakhale kuti ena a pyochromocytomas amatha kuoneka mu maselo a mitsempha, pafupifupi onsewa amapezeka mumodzi mwa ma glands a adrenal.
Ziphuphuzi ndi pafupifupi nthawi zonse osakhala ndi khansa, koma amafunikiranso chithandizo chifukwa cha mphamvu zawo zotulutsa mahomoni.
Mfundo za Pheochromocytoma ndi Kupanikizika kwa Magazi
- Pheochromocytomas imapanga mankhwala ambiri otchedwa catecholamines, omwe ndi mahomoni amphamvu okhudzana ndi kupsinjika maganizo, ndipo amachititsa mchitidwe wa mtima kuwonjezera kuchuluka kwa mtima, kuthamanga kwa magazi, ndi kutuluka kwa magazi.
- Ziphuphu izi zimabweretsa epinephrine (adrenaline), norepinephrine ndi dopamine - mankhwala atatu omwe ali pakati pa amphamvu kwambiri omwe amadziwika chifukwa cha kuwonjezeka kwa magazi . Thupi limagwiritsa ntchito mankhwala ang'onoang'ono kuti athe kuthana ndi zoopsa kapena zovuta.
- Ngakhale pang'onozing'ono, zonse zitatuzi zimakhala ndi zotsatira zowopsa pa magazi.
- Chifukwa pheochromocytomas imabweretsa kuchuluka kwa mahomoni onsewa, zotsatira za kupanikizika kwa magazi zimakhala zovuta kwambiri.
- Pafupifupi odwala onse okhala ndi pheochromocytomas awonjezera kuthamanga kwa magazi, ndipo chizindikiro cha kuthamanga kwa magazi kotere chifukwa cha vutoli ndikuthamanga kwa magazi kwambiri masana.
Zizindikiro ndi Zizindikiro za Pheochromocytoma
Gulu lachizindikiro la zizindikiro pa tsamba la pheochromocytoma limatchedwa "triad" ndipo limapangidwa ndi:
- Mutu
- Kutuluka thukuta kwambiri
- Tachycardia
Kuwopsa kwa magazi, nthawi zambiri kukwera kwambiri, ndi chizindikiro chofala kwambiri kwa odwala okhala ndi pheochromocytoma. Zina, zizindikiro zosadziwika bwino ndizo:
- Mavuto owonetsa (zovuta masomphenya)
- Kutaya thupi
- Kumva ludzu / kukodza
- Mshuga wamagazi wambiri
Zizindikiro zonsezi zimayambitsidwa ndi matenda osiyanasiyana, motero n'kofunika kuyesedwa ndi dokotala.
Kufufuza kwa Pheochromocytoma
Ambiri a pheochromocytomas amapezeka mwadzidzidzi ("mwadzidzidzi") pa mtundu wina wa kujambula (MRI, CT Scan). Matenda omwe amapezeka mwa njirayi amawoneka ngati khungu kakang'ono kamene kali kumadera ozungulira impso. Mbiri ya banja kapena mitundu ina ya mauthenga achizindikiro angasonyeze dokotala kuti pheochromocytoma ikhoza kukhalapo.
Ziphuphuzi zimagwirizananso ndi zina, zosawerengeka za majini. Kudziwa kawirikawiri kumaphatikizapo kuyesa mahomoni ambiri a magazi pa nthawi yochepa (maola 24 aliwonse), komanso kutenga zithunzi za chifuwa chonse ndi mimba. Nthaŵi zina "mayesero a zovuta" amachitidwa, komwe dokotala amalowa muyeso limodzi, kuyembekezera kanthawi kochepa, kenako amakhetsa magazi ndi cheke kuti awone ngati mankhwala ojambulidwawo akuwonjezera chiwerengero cha mahomoni ena m'magazi.
Matenda a Pheochromocytoma
Onse pheochromocytomas amafunika opaleshoni kuchotsedwa. Ngakhale kuti kuthamanga kwa magazi sikofunika kwambiri pa kusankha kapena ayi opaleshoni, iyi ndi imodzi mwa nthawi zochepa zomwe zimachitika pofuna kuchepetsa kuthamanga kwa magazi isanachitike opaleshoniyo.
Zifukwa izi ndi zovuta koma zimagwirizana ndi mfundo yakuti iyi ndi opaleshoni yowopsya komanso yoopsa.
Pofuna kuchepetsa chiopsezo, nthawi zambiri amachitapo kanthu, ngakhale zina mwazigawozi zimayambitsa kukhetsa magazi. Popeza kuti kuthamanga kwa magazi nthawi zambiri kumakwera kale, kuwonjezera kwina kungakhale koopsa. Opaleshoni yeniyeni idzachitidwa ndi katswiri ndi mayesero apadera adzachitidwa panthawi yomwe atachita opaleshoniyo kuti atsimikizidwe kuti chotupa chonsecho chinachotsedwa.
Zotsatira:
Baguet, JP, Hammer, L, Mazzuco, TL, et al. Zinthu zomwe anapeza pa phaeochromocytoma: kufufuza mozama kwa odwala 41 otsatira. European Journal of Endocrinology 2004; 150: 681.
Bravo, EL. Kusintha maganizo pa matenda a pathophysiology, matenda, ndi mankhwala a pheochromocytoma. Kupenda kwa Endocrinology 1994; 15: 356.
Oishi, S, Sasaki, M, Ohno, M, et al. Kusinthasintha kwa magazi nthawi zonse ndi kasamalidwe kawo kwa odwala okhala ndi pheochromocytoma. Lipoti la ndondomeko ndi kuwonanso kwa mabuku. Japan Heart Journal 1988; 29: 389.
Stein, PP, Black, HR. Njira yowonetsera yovuta ya pheochromocytoma. Kubwereza kwa mabuku ndi mbiri ya zomwe zinachitikira bungwe lina. Medicine (Baltimore) 1991; 70:46.
Ulchaker, JC, Goldfarb, DA, Bravo, EL, Novick, AC. Zotsatira za zotsatira za opaleshoni ya pheochromocytoma m'nthawi yamakono. Journal of Urology 1999; 161: 764.