Ubwino ndi Zoopsa za Sodium Nitroprusside
Nitroprusside ya sodium ndi mankhwala amphamvu kwambiri oletsa kuthamanga kwa magazi omwe amangogwiritsidwa ntchito pokhapokha ngati vuto la magazi liyenera kukhala panthaŵi yomweyo ndi kuchepetsedwa kwambiri. Mwachitsanzo, odwala omwe akudwala matenda oopsa kwambiri kapena kuthamanga kwambiri kwa magazi pamapeto pake opaleshoni ya mtima kapena magazi akhoza kupatsidwa nitroprusside ya sodium, yomwe ili ndi dzina la malonda a Nitropress.
Kuwonjezera pa kuchiza matenda oopsa, nitroprusside imagwiritsidwa ntchito pochita zinthu zina monga congestive mtima kulephera komanso kupitirizabe kuthamanga kwa magazi nthawi zina opaleshoni.
Ulamuliro wa Nitroprusside Sodium
Chifukwa chakuti imatha kuperekedwa kudzera mu intravenously, kugwiritsa ntchito sodium nitroprusside kumangokhala kuchipatala. Kuphatikiza apo, nitroprusside ya sodium ingayambitse kuthamanga kwa magazi kwakukulu kofulumira kumene kumafunikira kuyang'anitsitsa mosamala.
Momwe Sitidium Nitroprusside imagwirira Ntchito
Nitroprusside ya sodium ndi ya mankhwala omwe amadziwika kuti NO-kumasula mawotchi chifukwa amagwira ntchito potulutsa nitric okusayidi. Mofanana ndi mankhwala ena onse m'kalasiyi, nitroprusside ya sodium imagwira ntchito posangalala ndi mitsempha ya magazi. Kamodzi mu thupi, sodium nitroprusside mwamsanga imasweka mu nitric okusayidi, wamphamvu vasodilator. Mchere wa nitric umagwira ntchito ngati vasodilator, zomwe zimachititsa kuti mitsempha yambiri ya mitsempha ikhale yopuma, kuti mitsempha ya magazi iwonjezeke.
Pamene mitsempha ya magazi imakula, kuthamanga kwa magazi kumathamangira.
Kutaya kwa nitroprusside ya sodium ku nitric oxide kumachitika mofulumira kwambiri, motero sikungachedwetseke pakati pa kayendedwe ka mankhwala ndi kuchepetsa kuthamanga kwa magazi. Kuphatikizidwa ndi kuthamanga kwa magazi, kuchepetsa nitroprusside ya sodium kumasinthiranso ndondomeko ya magazi yomwe ikuyenda m'ziwiya zomwe zimadyetsa mtima, zomwe zimawathandiza kuchiza odwala omwe ali ndi vuto la mtima.
Mankhwala Ena Monga Sodium Nitroprusside
Mankhwala ambili a nitrate amagwiritsidwa ntchito pochiza kuthamanga kwa magazi ndi mavuto a mtima. Zonse ziwiri zotchuka nitrates ndi isosorbide dinitrate ndi nitroglycerin. Mankhwala onse a nitrate angagwiritsidwe ntchito pofuna kuthana ndi mavuto a mtima, ndipo ena, monga nitroglycerin, amagwiritsidwa ntchito pokhapokha pa cholinga chimenecho.
Nitroprusside Side Effects
Chotsalira choopsa kwambiri cha sodium nitroprusside ndi poizoni wa poizoni. Kutembenuka kwa sodium nitroprusside ku nitric oxide kumapangitsa cyanide ngati mankhwala. Pang'onopang'ono, cyanide iyi imayang'aniridwa ndi chiwindi, yomwe imasintha kukhala mankhwala osakanizika omwe amachotsedwa mwamsanga mumtsuko. Ngati amagwiritsidwa ntchito nthawi yaitali, kapena ngati agwiritsidwa ntchito nthawi imodzi, cyanide ikhoza kuthetsa chiwindi ndikuwombera poizoni. Pa chifukwa chimenechi, kasamalidwe kameneka kayenera kuthetsedwa ngati kuthamanga kwa magazi sikuyendetsedwa bwino pakatha mphindi 10 pa mlingo waukulu. Zizindikiro zodabwitsa zikuphatikizapo:
- Kusokonezeka
- Nausea
- Kutopa
Chithandizo choyamba ndicho kungosiya sodium nitroprusside ndikupereka chisamaliro chothandizira mpaka thupi lichotse cyanide.
Kusankha Chithandizo cha Kuthamanga Kwambiri kwa Magazi
Ndiwe ndi dokotala wanu okha amene mungasankhe mankhwala oyenera kuti muzitha kuchiza magazi.
Onetsetsani kuti mudziwe dokotala wanu ngati muli ndi mimba kapena akuyamwitsa, ndikupatsanso mayina a mankhwala ena ndi / kapena kuwonjezera mankhwala omwe mukuwatenga. Kumbukirani kuti mumaphatikizapo mankhwala owonjezera, monga aspirin kapena Advil (ibuprofen), ndi mankhwala ochizira.