Matenda a Ubongo Akukhala Oipa Kwambiri Nthawi
Matenda a Creutzfeldt-Jakob anamasuliridwa m'chaka cha 2000 pamene ku United Kingdom kunachitika milandu yambiri. Milandu imeneyi inkagwirizanitsidwa ndi zakudya zowonongeka ndi matenda a mimba (BSE), matenda a prion omwe amachititsa mitundu ina ya CJD, yomwe imatchedwa matenda a "ng'ombe yamisala".
Anthu ali ndi chifukwa chabwino chokhudzidwira za kutumiza kwa BSE kwa anthu.
Matenda osiyanasiyana a Creutzfeldt-Jakob, monga a mitundu ina ya matenda a Creutzfeldt-Jakob , akupita patsogolo mofulumira, akudwala matenda a mitsempha nthawi zonse. Koma matendawa ndi osowa kwambiri: Kuchokera mu October 1996 mpaka March 2011, ma 175 okha a vCJD anauzidwa ku United Kingdom, 25 ku France, 5 ku Spain, 4 ku Ireland, 3 ku Netherlands ndi United States of America ( USA), 2 ku Canada, Italy ndi Portugal, ndipo aliyense ku Japan, Saudi Arabia ndi Taiwan.
Zomwe Zimayambitsa Matenda ndi Kupewa Matenda (CDC) zimayang'anira zochitika ku United States za matenda onse a Creutzfeldt-Jakob.
Mitundu Yosiyanasiyana ya Matenda, Amafa Nthawi Zonse
Palibe mankhwala a matenda a Creutzfeldt-Jakob, omwe angathe kuchitika mwa munthu mwa njira zitatu:
- Pafupifupi 10 mpaka 15 peresenti ya milandu imatengedwa, chifukwa cha gene geneation.
- Mavuto ambiri amaoneka ngati akuwoneka mobwerezabwereza, mwa wina yemwe alibe mbiri ya banja lake.
- Kachigawo kakang'ono ka matenda amapezeka kudzera mu matenda, pogonana ndi matenda a ubongo. Pali zochitika zolembedwa zomwe zinachitika ngati zosagwirizana ndi njira zachipatala.
Matenda a Creutzfeldt-Jakob sagwiritsidwa ntchito m'njira yachizolowezi, monga kupopera kapena kukopa - palibe omwe amadziwika bwino omwe ali ndi zibwenzi kapena achibale awo omwe ali ndi kachirombo ka HIV.
Zakudya Zogwiritsa Ntchito Ng'ombe
Milandu ya matenda a Creutzfeldt-Jakob akuwoneka kuti akugwirizana ndi kudya zakudya zonyama zonyansa ku Ulaya. Nthenda yomweyo, ikapezeka nkhosa, ikutchedwa "scrapie." Amakhulupirira kuti zogwiritsidwa ntchito zogwiritsidwa ntchito ndi nkhosa zogwiritsidwa ntchito zowonongeka zimagwiritsidwa ntchito poperekera ng'ombe, ndipo ndi momwe ziweto zinayambira.
Asayansi apeza kuti zomwe zimayambitsa matenda a BSE, scrapie, ndi Creutzfeldt-Jakob sizowopsa kapena mabakiteriya monga matenda ena, koma oimira mapuloteni otchedwa prion. Choyamba chimasintha mapuloteni omwe amakhala opatsirana, omwe amawapha.
Zotsatira za ubongo
Popeza matenda a Creutzfeldt-Jakob amakhudza ubongo, zizindikiro zomwe zimabweretsa zimakhala zapadera. Zingayambe mwakuya ndi kusowa tulo, kupanikizika, kusokonezeka, umunthu ndi kusintha kwa khalidwe, ndi mavuto ndi kukumbukira, kugwirizana, ndi kuona. Pamene ikukula, munthuyo amakula mofulumizitsa matenda a maganizo komanso osasamala, kuyenda kosasinthasintha kotchedwa myoclonus.
Pachigawo chomaliza cha matendawa, wodwala amatha kugwira ntchito zonse zamaganizo ndi thupi, amatha kulowa m'thupi, kenako amamwalira. Kawirikawiri matendawa amatenga chaka chimodzi. Matendawa amakhudza anthu a zaka za pakati pa 50 ndi 75, komabe matenda osiyanasiyana a Creutzfeldt-Jakob adakhudza anthu ali aang'ono - ngakhale achinyamata (zaka zapakati pa 18 ndi 53).
Zovuta Kuzindikira
Palibenso chidziwitso chothetsera matenda a Creutzfeldt-Jakob, ndipo chitsimikiziro cha matendawa chingangopangidwa pambuyo pa imfa kupyolera mwazidziwitso. Popeza kuti matendawa ndi osowa, madokotala ena sangaganizire ngati matendawa ndipo akhoza kukhumudwitsa matenda ena a ubongo monga matenda a Alzheimer's kapena Huntington . Asayansi amati zatsopano, zovuta kuyesa ma laboratory m'tsogolomu zidzatha kuona mapepala amagazi a munthu amene ali ndi kachilomboka.
Zotsatira:
Collins, S., A. Boyd, A. Fletcher, MF Gonzales, CA McLean, CL Masters. "Kupitako patsogolo posachedwapa kufafanizidwa kwa matenda a Creutzfeldt-Jakob." J Clin Neurosci 7 (2000): 195-202.
"vCJD (Zosiyana ndi Matenda a Creutzfeldt-Jakob)." NCIDOD. 29 Nov 2006. Zomwe Zingayambitse Kuletsa ndi Kupewa Matenda. 28 Dec 2006 http://www.cdc.gov/ncidod/dvrd/vcjd.
Will, R., M. Zeidler, GE Steward, MA Macleod, JW Ironside, SN Cousens, J. Mackenzie, K. Estibeiro, AJ Green, R. Knight. "Kuzindikira matenda atsopano a Creutzfeldt-Jakob matenda." Ann Neurol 47 (2000): 575-582.
Wilson, K., C. Code, M. Ricketts. "Kuopsa kokhala ndi matenda a Creutzfeldt-Jakob kuikidwa magazi: Kukonzekera mwatsatanetsatane kafukufuku wotsutsa." BMJ 321 (2000): 17-19.