Matenda Ofanana ndi Parkinson koma Ndi Zosiyana Kwambiri
Wojambula wina wa ku Britain ndi wachikondi Dudley Moore adafa pa March 27, 2002, chifukwa cha imfa chomwecho chidalembedwa ngati chibayo. Koma, moona, Moore anali akulimbana ndi vuto lodziwika bwino lodziwika bwino la progresy palsy (PSP) lomwe limapangitsa kuti mbali zina za ubongo ziwonongeke mofulumira, kuyendetsa minofu, kugwira ntchito, kuzindikira ndi kuyendetsa ena mwadzidzidzi monga kumeza ndi diso kuyenda.
Zifukwa za Kukula kwa Mphulupulu ya Supranuclear
Ngakhale kuti chifukwa cha kupweteka kwapirinkikukukudziwika bwino sikukudziwikiratu, chinkaganiza kuti chikugwirizana ndi kusintha kwa mbali ina ya jini yotchedwa chromosome 17.
Mwatsoka, sizinthu zonse zomwe si zachilendo kusintha. Ngakhale kuti pafupifupi munthu aliyense ali ndi PSP ali ndi vutoli, choncho, awiri mwa magawo atatu a anthu ambiri. Kotero, kusinthika kwathukuwoneka kuti kumawathandiza m'malo mongowonjezera vutoli. Zoizoni zapansi ndi zina zokhudzana ndi majini zingasinthe gawo.
Asayansi samadziwansobe kuti PSP ikugwirizana bwanji ndi matenda a Parkinson kapena Alzheimer omwe amagawana zizindikiro zinazake.
PSP ikuyenera kuti iwononge munthu mmodzi mwa anthu 100,000 mosasamala mtundu, geography, kapena ntchito. Amuna amakonda kumakhudzidwa kwambiri kuposa akazi. Zizindikiro zimayambira pakati pa zaka 50 ndi 60.
Zizindikiro za PSP
Chimodzi mwa makhalidwe abwino kwambiri, "zizindikiro" za PSP zimaphatikizapo kuyendetsa kayendedwe ka maso, makamaka makamaka kuyang'ana pansi. Matendawa, omwe amadziwika kuti ophthalmoparesis, amachititsa kufooka kapena ziwalo za minofu inayake kuzungulira diso. Kusinthasintha kwa maso kumakhudzidwa kwambiri.
Pamene mkhalidwewo ukufalikira, kuyang'ana pamwamba kungawonongeke.
Chifukwa cha kusowa kwa mphamvu, anthu omwe ali ndi ophthalmoparesis nthawi zambiri amadandaula za masomphenya awiri, masomphenya osowa, komanso kumva mphamvu. Mavuto osowa maso a zikopa amatha kuchitika.
Monga mbali zina za ubongo zimakhudzidwira, PSP idzawonetsa ndi zizindikiro zambiri zomwe zimakhala zovuta kwambiri pakapita nthawi. Izi zikuphatikizapo:
- Kusasinthasintha komanso kusawonongeka
- General kuchepetsa kuyenda
- Kusuntha kwa mawu
- Kuvuta kumeza (dysphagia)
- Kutaya kwaiwala
- Maonekedwe a minofu
- Kutembenukira kumbuyo kwa mutu chifukwa cha kuuma kwa minofu ya khosi
- Kusakaniza kwamtendere
- Kusintha kwa khalidwe, kuphatikizapo imfa ya chilema ndi kutuluka mwadzidzidzi
- Kuchepetsedwa kwa lingaliro lovuta komanso losamveka
- Kutayika kwa luso la bungwe kapena kukonza (monga kuyang'anira ndalama, kutayika, kusunga malonjezo a ntchito)
Kuzindikira kwa PSP
PSP kawirikawiri sadziwa bwinobwino matendawa ndipo nthawi zambiri imatengeredwa ku matenda a mkati, matenda a chithokomiro, kupweteka, kapena matenda a Alzheimer (makamaka okalamba).
Kuzindikira kumapangidwa makamaka pogwiritsa ntchito zizindikiro. Ndi njira yomwe madokotala amafunika kuti asatuluke zina zomwe zingayambitse. Kujambula kwa magnetic resonance imaging (MRI) ya brainst ingagwiritsidwe ntchito kuthandizira matendawa.
Pa nthawi ya PSP, kaŵirikaŵiri zidzakhala zizindikiro za kuwonongeka (atrophy) mu gawo la ubongo lomwe limagwirizanitsa ubongo ku msana wa msana. Pa MRI, mbali ya ubongo uwu ingasonyeze zomwe ena amachitcha "penguin" kapena "hummingbird" chizindikiro (chotchulidwa chifukwa mawonekedwe ake ali ngati mbalame).
Izi, pamodzi ndi zizindikiro, kufufuza zosiyana, ndi kuyesedwa kwa majini, zingapereke umboni wofunikira kuti mudziwe.
Mmene PSP Imasiyanirana ndi Matenda a Parkinson
Pofuna kusiyanitsa PSP ndi Parkinson, madokotala adzalingalira zinthu monga chithunzi ndi mbiri yachipatala.
Mwachitsanzo, anthu omwe ali ndi PSP nthawi zambiri amakhala ndi malo owongoka kapena osamalidwa, pamene anthu omwe ali ndi Parkinson adzakhala ndi malo otsogolera.
Komanso, anthu omwe ali ndi PSP amatha kugwa chifukwa chosowa malire. Ngakhale anthu omwe ali ndi Parkinson ali ndi chiopsezo chachikulu chogwera, iwo omwe ali ndi PSP amakonda kuchita zimenezi kumbuyo chifukwa cha kuuma kwa mkhosi ndi msana.
Pomwe zikunenedwa, PSP imaonedwa kuti ndi mbali ya matenda opatsirana ndi matenda omwe amatchedwa Parkinson-plus syndrome omwe ena amakhalanso ndi Alzheimer's.
Njira Zothandizira
Palibe mankhwala enieni a PSP. Odwala ena angayankhe mankhwala omwewo omwe amagwiritsidwa ntchito kuti asamalire Parkinson, monga levodopa , ngakhale kuti yankho limakhala losauka (lingaliro loti limatengera matenda).
Mankhwala ena opatsirana pogonana, monga Prozac, Elavil, ndi Tofranil, angathandize ndi zizindikilo zina kapena zizindikiro zomwe munthu angakhale nazo. Kuwonjezera pa mankhwala, magalasi apadera (bifocals, prisms) angathandize ndi mavuto owona, pamene zothandizira kuyenda ndi zipangizo zina zowonongeka zingapititse patsogolo kuyenda ndi kuteteza kugwa.
Ngakhale kuti mankhwala opaleshoni sangasinthe mavuto a magalimoto, angathandize kusunga maulamuliro a ziwalo ndikuletsa kuwonongeka kwa minofu chifukwa chosagwira ntchito. Panthawi yovuta dysphagia, chubu chodyetsa chingakhale chofunika.
Ma electrode opangidwa ndi makina oyambitsa magetsi omwe amagwiritsidwa ntchito mu ubongo wopangitsa kuti Parkinson asathenso kuthandizira kuti athetse PSP.
Mawu Ochokera
Ngakhale kuti sakudziwa za PSP ndi njira zochepetsera chithandizo, nkofunika kukumbukira kuti matendawa alibe njira ndipo amasiyana kwambiri ndi munthu aliyense. Pokhala ndi kuyang'anitsitsa kwachipatala komanso zakudya zabwino, munthu amene ali ndi PSP angathe kukhala ndi moyo kwa zaka zambiri, ngakhale atatha zaka makumi ambiri, atagwiritsidwa ntchito.
Kwa anthu ndi mabanja omwe amakhala ndi matendawa, ndikofunika kufunafuna chithandizo kuti muteteze kudzipatula komanso kuti mudziwe zambiri zokhudza odwala. Izi zikuphatikizapo mabungwe monga CurePSP yatsopano ya New York City yomwe imapereka magulu a anthu othandizira payekha komanso pa intaneti, bukhu la madokotala azatswiri, ndi gulu la othandizira anzawo ophunzitsidwa.
> Chitsime:
> Ling, H. "Njira Yopititsira Patsogolo Kukula Kwambiri Kwambiri Kwambiri Kwambiri." Journal of Trouble Movement. 2016; 9 (1): 3-13.