Michael J. Fox, wa zaka 54, amadziwika ndi zinthu zambiri. Wochita masewera olimbitsa thupi, wapambana mphoto kwa ntchito yake mu "Mbale," "City Spin," ndi "The Good Wife." Komabe, kupindula bwino kwa Fox - Grammy, Emmys, ndi Golden Globe Awards pambali - kungakhale ntchito yake kuthetsa matenda a Parkinson. Wojambulayo adakhazikitsa Michael J. Fox Foundation ya Parkinson's Research (MJFF) mu 2000, zaka zisanu ndi zinayi atapezeka kuti ali ndi vutoli.
Chifukwa chodziwitsa anthu zachipatala m'chaka cha 1998, Fox wanena kuti akuthandizira kufufuza zowonongeka kwa maselo ndipo wagwira ntchito mwakhama kuti apeze ndalama zofufuza. Fox panopa ndi amene anayambitsa bungwe ndipo akukhala pa bwalo la oyang'anira.
Michael J. Fox Foundation ya Research of Parkinson
Michael J. Fox Foundation ya Research of Parkinson ikudzipereka kupeza chithandizo cha matenda a Parkinson. Mpaka pano, maziko adakweza zoposa 450 miliyoni pofuna kufufuza za Parkinson. MJFF imalimbikitsanso kulandira chithandizo chamankhwala pa zizindikiro za matendawa - monga kudzimbidwa, mavuto omeza, kuwonongeka, komanso kuchepa kwa chidziwitso - komanso zotsatira zovulaza za mankhwala a Parkinson.
Matenda a Parkinson ndi chiyani?
Matenda a Parkinson amakhudza dongosolo la mitsempha lopangitsa kuti thupi liziyenda.
Chizindikiro chozindikiritsa cha chikhalidwe ndi mantha, makamaka m'manja. "Parkinson's" ndilo lonse la magawo asanu ndi limodzi a matendawa, omwe ambiri amakhudza anthu a zaka zapakati pa 50. Akuluakulu omwe ali ndi zaka makumi asanu ndi awiri (62) ali ndi zaka 62. Pafupifupi anthu amodzi miliyoni ku America ali ndi matenda a Parkinson.
Pafupifupi 30 peresenti ya anthu omwe ali ndi Parkinson amapezeka kuti asanakwanitse zaka 50 - 20 peresenti ya anthuwa amapezeka asanafike zaka 40. Parkinson akamakula asanakwanitse zaka 50, amadziwika kuti ndi Parkinson. Michael J. Fox, amene anapezeka ali ndi zaka 30, ali m'gulu ili.
Anthu omwe ali ndi matenda a Parkinson ali ndi kusowa kwa mankhwala omwe amachititsa kusuntha (kutchedwa dopamine) mu ubongo wawo. Izi zimayambika ndi kusintha kwa maselo a nigra, a m'bongo omwe amapanga dopamine. Momwe kusintha kumeneku kumachitikira sikudziwika. Zolingaliro zikuphatikizapo kukalamba msanga, kutengeka kwa chibadwa, ndi zochitika zachilengedwe, pakati pa ena. Zikuoneka kuti matenda a Parkinson amayamba chifukwa cha kuphatikiza zinthu izi.
Kupeza Chithandizo
Chithandizo cha matenda a Parkinson kawirikawiri amakhala ndi mankhwala omwe angapangidwe kukhala dopamine mu ubongo (Sinemet), kapena mankhwala omwe amawoneka kuti amakhudza kugwiritsa ntchito dopamine mu ubongo (Symmetrel, Eldepryl). Chithandizo chingaphatikizepo dopamine agonists (Parlodel, Permax, Mirapex, Requip), zomwe zimayambitsa maselo a ubongo a dopamine.
Njira zopangira opaleshoni zilipo. Imodzi mwa opaleshoni yotchuka kwambiri ndi opaleshoni ya ubongo (DBS).
DBS inakhazikitsidwa mu zaka za m'ma 1990 ndipo tsopano ndiyo njira yeniyeni yothetsera vutoli. Ngakhale kuti DBS ingathandize kuthana ndi zizindikiro, sizimachiza matendawa kapena zimalepheretsa kupita patsogolo. Njira ya Thalamotomy ndi pallidotomy, zomwe zimawononga maselo "ovuta" m'bongo pogwiritsa ntchito electrode, amapezekanso.
Zotsatira
Michael J. Fox Foundation ya Research of Parkinson (2016)
The Parkinson's Disease Foundation (2016)