Tisanayambe, ndikufuna kuti anthu omwe ali ndi chidwi pa nkhani yonse yothandizira matenda opatsirana pogonana , nkhaniyi yokhudza chiphaso cha testosterone iyenera kuwerengedwera mu nkhani zina ziwiri zomwe ndalemba: piritsi lachikazi lopanda kukondweretsedwa . Kwenikweni, chiphaso cha testosterone chimaimira chigawo cha pakati pa chiwopsezo cha chiwerewere ichi: njira yomwe inayesedwa pambuyo Pfizer anasiya kukakamiza Viagra kwa amayi komanso chisanafike chitukuko cha flibanserin, mankhwala osokoneza bongo omwe amachititsa kuti thupi liziyenda bwino.
Kafukufuku Wokhudzana ndi Kugonana kwa Akazi
Kuwongolera kwa zoyesayesa zonse zothandizira zochitika zapakati zochitika zogonana mpaka chaka cha 1999 chomwe chinafalitsidwa mu JAMA chomwe chimatchulidwa kuti "43-31". Akatswiri ofufuza apeza kuti akazi oposa 4 (10%) ali ndi vuto la kugonana poyerekeza ndi amuna 31 peresenti. Phunziroli linafotokoza zomwe zikupitirira kutsutsana pazochitika zonse zokhudza chithandizo cha kugonana kwa amayi; phokoso limene limaphatikiza makampani opanga mankhwala ndi akatswiri ambiri okhudza kugonana kumbali imodzi, ndipo otsutsa amanena kuti kugonjetsa kugonana ndi chitsanzo china cha "matenda ozunguza" kumbali inayo.
Pa June 21, 2004, Proctor & Gamble adapempha kuti FDA ivomereze dongosolo la testosterone yatsopano (jargonese for testosterone patch), Intrinsa. Intrinsa inalinganizidwa monga:
Kuchiza kwa chisokonezo chokhudzana ndi kugonana pakati pa amayi opatsirana opatsirana pogonana omwe amalandira chithandizo cha conjection estrogen. Matenda a chilakolako chogonana (HSDD) ndi kusowa kosalekeza kapena kupezeka kwa malingaliro ogonana, malingaliro, ndi / kapena kukhumba kapena kuvomereza kugonana, komwe kumayambitsa zovuta zaumwini kapena zobvuta. Chilakolako chogonana chikhoza kugwirizanitsidwa ndi kugonana kochepa, mavuto okhudzana ndi kugonana kapena vuto lachilakolako.
Monga tafotokozera m'mbuyomo zokhudzana ndi kugonana kwa amayi , HSDD ndi nthawi yakale. Masiku ano, DSM-5 imalankhula za "chilakolako cha chilakolako cha kugonana / chilakolako cha kugonana" chomwe chikuphatikizapo mavuto a chilakolako ndikukwera ku chipatala chimodzi.
Zotsatira za mayesero a P & G a Phase 3 amasonyeza kuti mwa amayi omwe ali ndi zochitika zogonana ziwiri kapena zitatu pamwezi, kulamulira kwa 300 μg (koma osati 150 μg kapena 450 μg) kunalumikizidwa kuchithunzi chimodzi chokhutiritsa kugonana mwezi uliwonse.
Pa zifukwa ziwiri zomveka, a FDA anakana kuvomereza Intrinsa. Choyamba, zotsatirazi ndizopanda phindu. Kwa anthu omwe ali ndi chizoloŵezi chogonana nthawi zonse komanso chokhutiritsa , chiphaso cha testosterone chikuwonjezera chiwerengero cha zochitika zokhudzana ndi kugonana ndi mwezi umodzi! Chachiwiri, chifukwa chogonana chimodzi chokha chokhutiritsa, amayi omwe ali ndi vuto la kusintha kwa opaleshoni omwe ayamba kale kutenga estrojeni akhoza kupezeka ku mahomoni ena omwe angakhale oopsa, a testosterone. Ndiloleni ndifotokoze.
Panthawi yomwe P & G adafunsira kuti ayambe kuvomereza testosterone chigambacho, aliyense anali kutuluka kunja kwa zotsatira za maphunziro a Women's Health Initiative akuyang'ana mahomoni a supplementation. Panthawiyi, zotsatira za maphunzirowa zinkasonyeza kuti kasamalidwe ka estrogen ndi progesterone kwa amayi pambuyo poyeretsa chiwopsezo chimaonjezera chiopsezo cha zochitika zowopsya (kuganiza zolimbitsa thupi), zochitika za mtima ndi khansa ya m'mawere. A FDA anatsimikiza kuti popanda maphunziro a nthawi yayitali, zingakhale zoopsa kupatsa akazi a postmenopausal testosterone ndi mahomoni ena. Zindikirani, kufufuza koyambirira kwa P & G kunayesedwa testosterone supplementation mwa ophunzira kwa masabata 52 makamaka.
Malingana ndi chidzudzulo cha FDA, P & G adawona zopanda phindu zokankhira nkhaniyi ndi kutaya Intrinsa.
Poyang'anapo, zikuonekeratu kuti P & G akuyembekeza kuti madokotala angapereke chiphaso cha testosterone kuti chigwiritsidwe ntchito pamalopo-makamaka mwa amayi ena kupatula omwe adakumana ndi chiopsezo chakumbuyo kwa opaleshoni. Chifukwa cha kusowa kwa nthawi yaitali, a FDA adawopsya ndi mwayi umenewu.
Palinso zofukufuku zina zomwe zimatsutsanso kuti mphamvu ya testosterone ndiyothandiza bwanji anthu omwe ali ndi vuto la kugonana / chilakolako cha kugonana. Choyamba, ife tiribe umboni wa ntchito yochepa ya androgen kwa amayi omwe ali ndi vuto la kugonana. Chachiwiri, ngakhale kuti tingathe kuyeza intracrine kapena ma testosterone osakanikirana, sitimatha kuchuluka kwa testosterone m'magulu akuluakulu a mitsempha.
Masewera a Testosterone mkatikati mwa mitsempha yapamwamba amakhala ndi zotsatira zowonjezera komanso kukhumba.
Kodi Akazi Amafunikira Testosterone Yambiri?
Mwa kuyankhula kwina, sitidziwa ngati testosterone imafika mu ubongo ndi msana wa iwo omwe ali ndi vuto la kugonana lachikazi ndilokwanira mokwanira kuti apeze testosterone supplementation yodabwitsa, kuyamba ndi kuyamba. Chachitatu, ngakhale m'magalasi a testosterone omwe amapangidwa kuti azisamalira amuna, sitikudziwa momwe testosterone imathandizira kuti tichite testosterone supplementation zambiri.
Koma apa pali chinthucho. Kwa amayi ambiri, kupezeka kwa testosterone m'njira ina n'kotheka. Mwachitsanzo, amayi omwe ali ndi matenda okhudzana ndi kugonana / chilakolako chogonana angathenso kupatsidwa ma telo a testosterone ndi zizindikiro zopanda mankhwala (kutenga mankhwala a amuna). Testosterone zowonjezeranso zowonjezera zimabwera ndi mitundu ya naturopathic yomwe ingagulidwe pa intaneti. Pomalizira, m'mayiko ena, nthawi zina testosterone imaperekedwa kwa amayi omwe ali ndi vuto la kugonana kwa amayi.
Choncho zonsezi, pali njira zopezera testosterone manja kuti asamalidwe ndi kugonana kwa amayi ; Komabe, tapatsidwa zomwe tikudziwa, ndizo lingaliro loyenera kuchotsa zinthuzo. Kafukufuku samasonyeza kuti pulogalamu ya testosterone supplementation imathandiza kwambiri amayi omwe ali ndi vuto la kugonana lachikazi, kuphatikizapo sitidziwa ngakhale ngati ma teti a testosterone ndi ofooka kwa amayi omwe ali ndi vuto logonana. Ndipo, ndithudi, testosterone ndi hormone, ndipo mahomoni akhala akudziwika kuti akhoza kukhala ndi zotsatira zowawa monga stroke, magazi, khansara ndi zina zotero.
> Zotsatira:
> Mutu > wotchedwa "Testosterone mankhwala ochepetsera libido mwa amayi" mwa R Basson wofalitsidwa mu Kupititsa patsogolo kwachipatala mu Endocrinology ndi Metabolism yofalitsidwa mu 2010. Anapezeka pa 3/13/2015.
> Nkhani > yotchedwa "Kusintha kwa Chiwawa: Makampani Opanga Mankhwala Oyesera Kugwiritsa Ntchito Mankhwala Osokoneza Bongo kwa Akazi" ndi Heather Hartley atafotokozedwa mu Sexualities mu 2006. Anapezeka pa 3/15/2015.