Kufufuza momwe Viagra amagwiritsira ntchito pa chilakolako cha kugonana / chiwonongeko chachikazi
Kuyambira pachiyambi chakumayambiriro kwa nyengo, chiwopsezo cha kugonana kwa amayi (FSD) chakhala chikuwombera, ndi makampani osokoneza bongo ndi akatswiri ena azachipatala (taganizirani alongo a Berman) ndikuwongolera chifukwa chake. Chidwi chonsechi n'chopanda nzeru; mmbuyomo mu 2005, msika wa Zofalitsa za FSD unali wokwana madola 1.7 biliyoni.
Mpaka pano, pakhala palibe mapiritsi ovomerezedwa ndi FDA kuti azisamalidwa ndi FSD.
Koma, ndikukhulupirirani, palibe chivomerezo cha FDA sikuti ndikulephera. Choyamba, Pfizer anayesera kutsimikizira kuti mankhwala ake a juggernaut angathandize ndi FSD. Chachiwiri, mu 2004, P & G anayesera kugulitsa FDA pa testosterone chigamba, Intrinsa. Nthawi sizingakhale zovuta. Mwatsopano ku Vioxx, kudabwa kwambiri ndi FDA kunanena za nkhawa za intrinsa zomwe zimatanthauza kuteteza komanso chitetezo. Posachedwapa - ndipo palibe - Sprout Pharmaceuticals amayesa kupeza mankhwala ake opatsirana pogonana, flibanserin, ovomerezeka.
Poyesera kupereka ndemanga yeniyeni ya mankhwala operekedwa kwa FSD, ndayesedwa kufufuza njira zitatu zomwe zikugwirizana ndi chikhalidwe ichi m'magawo atatu osiyana. Nkhaniyi ikufotokoza momwe Viagra amagwiritsira ntchito amayi, nkhani yachiwiri ikufufuza chigamu cha testosterone, ndipo nkhani yachitatu ikuyang'ana flibanserin . Komabe, ngakhale P & G akusiya mayesero awo pa chiopsezo cha amayi mu 2004, ndipo FDA imatseka Intrinsa chaka chomwecho, madokotala ena adakali kupereka mankhwala osokoneza bongo ndi testosterone kwa amayi omwe ali ndi FSD.
Flibanserin, komabe, siyenela kuvomerezedwa.
Kodi Chiwawa Chimachitika Bwanji?
Viagra ndi inhibitor ya phosphodiesterase ya mtundu wa 5 (PDE5). Imathandizira kupanga guanosine monophosphate. Guanosine monophosphate imayambitsanso maselo osasuntha ndi vasodilates ndikuwonjezera magazi kupita ku ziwalo zoberekera. Monga ife tonse tikudziwira, mwa amuna, Viagra zotsatira ndi erection.
Komabe, PDE5 imasonyezedwanso mu minofu yosalala ya vagini, clitoris, ndi labiya zomwe zimapangitsa kuti vaginal vaginal and clitoris erection. Amakhulupirira kuti mwa amayi omwe ali ndi chifukwa cha FSD, magazi amapita kumaliseche amachepetsedwa. Pazowonjezereka, kafukufuku amasonyeza kuti mwa amayi ena omwe ali ndi matenda a atherosclerosis, magazi amapita kumaliseche amachepetsedwa.
Monga mankhwala onse, Viagra imakhala ndi zotsatira zoyipa kuphatikizapo kupweteka mutu, kupweteka, kunyowa, kusokonezeka kwa maso ndi zina zotero. Kuwonjezera apo, anthu omwe amatenga nitrates kuti athetse angina ayenera kupewa Viagra chifukwa cha mantha a hypotension kapena kutsika kwa magazi.
Kugonana Kwachikazi (FSD) Malingaliro
Pakalipano, kugwiritsiridwa ntchito kwa Viagra kuli ndi amayi omwe ali ndi mtundu wina wa FSD wotchedwa kugonana ndi chilakolako chogonana . Mawu awa ndi atsopano ndipo athandizidwa mu DSM-5. Mkazi wachikazi / chilakolako chogonana chingatanthauzidwe monga zotsatirazi:
- Kukhumudwa kopanda (kapena kuchepetsedwa) kugonana ndi chidwi chokhudzidwa chokhudzana ndi kugonana. malingaliro ogonana, chidwi pa kugonana, kukondweretsa thupi, kuyamba kugonana ndi zina zotero;
- Miyezi isanu ndi umodzi yokha kapena yoposa;
- Osati bwino kufotokozedwa ndi matenda ena kapena zikhalidwe;
- Kaya moyo wanu wonse kapena wopeza;
- Zonsezi kapena zachikhalidwe;
- Ofatsa, ochepa kapena ovuta kwambiri.
Monga momwe nthawi zina zimakhalira ndi kafukufuku wowonjezera, kusagwirizana koyambirira kwa kugonana kunabweretsa zotsatira zafukufuku. Mwapadera, maphunziro oyambirira okhudza mankhwala osokoneza bongo anagwiritsidwa ndi mawu otchulidwa kale omwe amachititsa mavuto ndi kudzutsa mavuto ndi chilakolako m'magulu awiri osiyana: matenda okhudzana ndi chiwerewere ndi kugonana kwachisokonezo .
Pazifukwa zina, mitundu ina ya FSD imaphatikizapo matenda a orgasmic odwala, ululu wa genito-pelvic / matenda opatsirana, ndi mankhwala osokoneza bongo / mankhwala.
(Mwachiwonekere, DSM imakwera.)
Kafufuzidwe pa Zachikazi M'mayi
Phunziro lapamwamba kwambiri lomwe limasonyeza kuti Viagra lingapindulitse akazi ndi FSD lapangidwa ndi Dr. Jennifer Berman, wogonana ndi wogonana, ndi Dr. Laura Berman, katswiri wa zachipatala ndi urologist, akadali mu maphunziro. Zotsatira za zomwe apeza zikusonyeza kuti Viagra ikhoza kuyambitsa ntchito yogonana mwa amayi omwe ali ndi mavuto odzutsa, koma osati amayi omwe ali ndi zofuna zawo. Komanso, zotsatira za phunziroli zinali zolemedwa ndi zotsatira za heavyboat.
Tiyenera kuzindikira kuti alongo Achilendo ali ndi maganizo awo kuphatikizapo a Dr. Heather Hartley, a "public" ndi a zachipatala komanso ovomereza zaumoyo azimayi amene adatsutsa kwambiri mankhwalawa. N'zomvetsa chisoni kuti Hartley anamwalira ali ndi zaka 39. (Hartley anali moyo wosachepera.)
M'nkhani ya 2006 yotchedwa "The 'Pinking' ya Viagra," Hartley amatsutsa kwambiri alongo a Berman. Amatsutsa alongo ngati "odziwa kugwiritsa ntchito makampani kuti azilimbikitsa malonda awo." Hartley amatsutsanso anthu a Bermans omwe amawakonda kwambiri mankhwalawa. Komanso, adanena kuti alongo a Berman '"anapitirizabe kunena kuti Viagra ndi zina zoterezi zimagwiritsa ntchito mankhwala osokoneza bongo kwa amayi amasonyeza kuti achoka pazochitika za sayansi ndikuvomereza chikhalidwe cha Viagra."
Chochititsa chidwi ndi chakuti Hartley amajambula chithunzi cha alongo Achimwene monga ochita zofuna zawo kuti azipereka ndalama zambiri pazochita zawo zamalonda. Hartley amanena kuti kupambana kwa Bermans kumaphatikiziridwa ndi kuwonetserana kwapadera kwa cholinga chokulitsa "kukhala ndi chibwenzi ndi momwe amaonera anthu, monga umboni, mwachindunji, ndi kugwirizana pa webusaiti yawo kuvidiyo ya" yosamalitsa "ya Jennifer wosankha kubadwa, kumaliza ndi zofotokozera zake za momwe iye amachira. "
Zaka zaposachedwapa, alongo a Berman akhala ndi mwayi wofalitsa nkhani. Panopa, Jennifer Berman ndi mmodzi mwa a Madokotala , ndipo Laura Berman ndi wolimba kwambiri ndi Oprah ndi Dr. Oz.
Ndi zosiyana kwambiri ndi maphunziro a Berman, kafukufuku wina wasonyeza kuti Viagra sichigwira ntchito pochiza nkhani zodzutsa ndi zofuna. Mwachitsanzo, vuto linalake lolamulira la Basson ndi anzake linasonyeza kuti Viagra sizinayambe kusintha kwakukulu pachithupi cha kugonana pakati pa amayi awiri omwe ali ndi amayi omwe amachititsa chiwerewere. Kafukufuku wina anawonetsa kuti chifukwa cha kuchepa kwa PDE5 m'munsi mwa chiberekero ndi msinkhu poyerekeza ndi mbolo, zotsatira za Viagra zimachepetsedwa mwa amayi.
Ngati inu kapena wokondedwa wanu mukukumana ndi chilakolako cha kugonana / chiwopsezo chachikazi monga momwe DSM-5 ikufotokozera, mwina mukuganiza ngati mutenga Viagra. Ponena za vutoli, ndikukupatsani ndemanga ya ndemanga ya 2014 ya Lo Monte ndi anzake kuchokera ku Drug Design, Development and Therapy :
FSAD [chilakolako cha kugonana / chivomezi chaukwati] ndi matenda ovuta, omwe ali ndi chifukwa chovuta kuchidziwitsa. Kufufuza koyambirira kwa mbiri yokhudza kugonana, maganizo, ndi zachipatala ndiloyenera kuti pasapezeke matenda omwe angatengeke komanso kuzindikira mtundu wa FSAD. Ma Generalists ayenera kuyendetsa dziko lonse lapansi kwa wodwala ndi zovuta zokhudzana ndi kugonana, ngakhale kuti mankhwala osagwiritsa ntchito mahomoni monga PDE5 inhibitors (mwachitsanzo, sildenafil citrate) [Viagra] ayenera kusungidwa ngati njira yotsiriza.
M'mawu ena, mungafune kuganizira za Viagra ngati mankhwala otsiriza pambuyo pofufuza mwatsatanetsatane za chilakolako chanu chogonana / matenda opatsirana ndi dokotala wamkulu [kapena katswiri].
Zotsatira
Mutu wotchedwa "Chitetezo ndi Mphamvu ya Sildenafil Citrate for Treatment of Women's Sexual Arousal Disorder: Phunziro Lolimbitsa Thupi Lachiwiri, JR Berman, LA Berman, omwe analemba nawo buku lofalitsidwa mu Journal of Urology mu 2003. Atapezeka pa 3 / 15/2015.
Nkhani yotchedwa "The Pinking of Viagra Culture: Mankhwala Ogwiritsa Ntchito Mankhwala Ogwiritsa Ntchito Mankhwala Ogwiritsa Ntchito Mankhwala Ogwiritsa Ntchito Mankhwala Ogwiritsa Ntchito Mankhwala Osokoneza Bongo" ndi Heather Hartley anafalitsidwa mu Sexualities mu 2006. Anapezeka pa 3/15/2015.
Nkhani yonena kuti "akazi omwe amatenga" mapiritsi a buluu "(sildenafil citrate): chinthu chachikulu choterechi?" inalembedwa mu Drug Design, Development and Therapy mu 2014. Inapezeka pa 3/15/2015.