Mtundu wa Matenda a Nyamakazi Kawirikawiri Amadziwika Ngati Gout
Matenda a calcium pyrophosphate (CPPD) ndi mtundu wa nyamakazi. Amayambitsa makatani a calcium phosphate m'magulu ndipo ali ndi makhalidwe ofanana ndi gout. Nkhondo ya CPPD ikhoza kuchitika mwadzidzidzi ndipo imachititsa ululu, kutupa, ndi kulemala.
CPPD imadziwika ndi mayina ena kuphatikizapo pseudogout , mawu achikulire omwe adagwiritsidwanso ntchito muzochita zambiri zachipatala, ndi chondrocalcinosis , yomwe imatchulidwa mwachindunji ndalama za calcium zomwe zimakhala m'malo ophatikizana.
Zizindikiro
Ndi CPPD, kupangika kwa calcium m'mapangidwe kungachititse kuti zizindikiro za nyamakazi zikhale zopweteka, kuphatikizapo kupweteka, kutupa, kutopa, kutentha thupi, komanso kuthamangitsidwa.
Chiopsezo cha CPPD chimawonjezeka ndi zaka. Malingana ndi kafukufuku wochokera ku American College of Rheumatology, chitukuko cha makandulo a calcium chimapezeka pafupifupi pafupifupi atatu mwa anthu akuluakulu ali ndi zaka 50. Chiwerengero chimenecho chikuwonjezeka kufika pafupifupi 50 peresenti panthawi yomwe munthu amafikira 90.
Sikuti aliyense amene amapanga CPPD kristalo adzawona zizindikiro. Pa 25 peresenti omwe amachita, ambiri amakhala ndi zowawa zopweteka zokhudzana ndi mawondo kapena kumva ululu ndi kutupa pamapazi , mabala , manja , mikono , kapena mapewa . Kuthamanga kwa CPPD kumatha masiku angapo kupita masabata angapo.
Kuthamanga kwa CPPD kungayambitse matenda aakulu, opaleshoni, kupwetekedwa mtima, kapena kupambanitsa kwambiri. Kwa zaka zambiri, matendawa amachititsa kuti ziwalo zowonongeka ziziyenda bwino, zomwe zimayambitsa kulemala kwa nthawi yaitali.
Pafupifupi asanu pa anthu 100 alionse odwala matendawa amayamba kukhala ndi matenda a nyamakazi odwala matenda a nyamakazi, omwe ali ngati ziwalo zozungulira (kutanthauza ziwalo zofanana pambali zosiyana siyana za thupi, monga zida kapena mawondo).
Kudziwa
Kafukufuku wa CPPD nthawi zambiri amachedwa chifukwa zizindikiro zimakhala zolakwika chifukwa cha matenda ena a nyamakazi monga osteoarthritis , nyamakazi yamagazi, ndi gout (matenda omwe amadziwika ndi kupanga ma uric acid).
Matendawa amayamba kukhala ndi aspirin yamadzimadzi kuchokera kwa ophatikizidwa omwe akugwiritsidwa ntchito komanso kusanthula kwa depositall deposits mu labata.
Dokotala akhoza kuitanitsa mayeso ojambula monga ultrasound, scanned computing tomography (CT) , kapena kujambula kwa maginito (MRI) kuti athandizire kuzindikira mawerengedwe ozungulira pamodzi.
Chithandizo
Mosiyana ndi gout, momwe uric acid amakristasi amatha kusungunuka ndi mankhwala, makristasiwa amaphatikizapo CPPD osasungunuka (kutanthauza kuti sangathe kusungunuka).
Choncho, chithandizochi chikuwongolera kuchepetsa zizindikiro ndi kupeĊµa chiwonongeko cha mtsogolo. Njira zamankhwala ndizo:
- Mankhwala otsutsana ndi kutupa (nonsteroidal anti-inflammatory drugs (NSAIDs) kuti athetse ululu ndi kutupa
- Colcrys yochepa (colchicine) , yomwe imagwiritsidwa ntchito kwambiri kwa gout, kwa anthu omwe sangalekerere NSAIDs
- Mankhwala a Cortisone (steroid) m'magulu okhudzidwa kuti apereke chithandizo chokhazikika, chachangu kwa kutupa
- Plaquenil (hydroxychloroquine) kapena methotrexate (MTX) pa milandu yowopsa kwambiri pofuna kuteteza chitetezo cha mthupi ndi kuchepetsa kutupa
Kuchita opaleshoni kungatengedwe kuti kuchotsa chiwerengero chowerengeka kuchokera ku mgwirizano, ngakhale kuti chikayesedwa kuti chiyesedwe ndi deta yochepa kuti zithandize ntchito yake.
> Zotsatira:
> American College of Rheumatology. "Calcium Pyrophosphate Deposition (CPPD)." Atlanta, Georgia; zasinthidwa mwezi wa March 2017.
> Schlee, S .; Bollheimer, L .; Bersch, T. et al. "Crystal Arthritides: Gout ndi Calcium Pyrophosphate Arthritis / Gawo 1: Epidemiology ndi Pathophysiology." Zina Gerontol Geriatr. 2017. DOI: 10.1007 / s00391-017-1197-3.