Mankhwala Osokoneza Bongo ku America ndi Padziko Lonse

Methimazole, Carbimazole ndi Propylthiouracil / PTU

Matenda a chithokomiro akayamba kugwiritsidwa ntchito kwambiri - matenda omwe amadziwika kuti hyperthyroidism - gland imatulutsa mahomoni ambiri a chithokomiro. Izi zikhoza kuchititsa zizindikiro zosiyanasiyana, kuphatikizapo kuthamanga msanga, kuthamanga kwa magazi, nkhawa, kusowa tulo, kutenthedwa, kutaya thupi, kutsegula m'mimba, ndi zizindikiro zambiri za kuchepetsa mphamvu ya metabolism, ndi zilonda zopitirira mphamvu komanso ziwalo.

Chithandizo chachikulu cha hyperthyroidism ndi gulu la mankhwala omwe amadziwika kuti mankhwala osokoneza bongo. Mankhwala otchedwa Antithyroid amatchedwanso thioamides. Ndi mankhwala omwe amagwiritsidwa ntchito pochizira chithokomiro chowopsa - hyperthyroidism - kuphatikizapo chithokomiro chikutha mphamvu chifukwa cha matenda a Graves, goizdous toxic multinodular goiter, kapena mitsempha ya poizoni.

Mankhwala a Antithyroid amachititsa kuti chithokomiro chisamapange mphamvu yotulutsa timadzi timene timene timatulutsa tizilombo thyroxine (T4) ndi triiodothyronine (T3).

Mankhwala othandizira tizilombo toyambitsa matenda ku United States ali ndi methimazole ndi propylthiouracil (PTU). Kunja kwa United States, zosankhazo ndi methimazole, carbimazole, ndi PTU.

Methimazole

Mankhwala otchedwa antithyroid mankhwala a methimazole amaletsa chithokomiro kuti asagwiritse ntchito ayodini - kawirikawiri kuchokera ku zakudya kapena zowonjezereka - kuti apange hormone ya chithokomiro. Ndi mankhwala amene amatengedwa kamodzi patsiku ndi odwala.

Nthaŵi zina Methimazole amatchedwa thiamazole.

Mankhwala awa amagwiritsidwa ntchito kuzungulira dziko lapansi ndipo ndi mankhwala oyambirira a antitroyroid omwe amagwiritsidwa ntchito ku United States, kumene amapezeka pansi pa dzina lakuti Tapazole.

Okonzanso angapo amaperekanso mtundu wa methimazole.

Carbimazole

Carbimazole ndi mankhwala omwe, atagwiritsidwa ntchito, amatembenukira ku mankhwala a methimazole m'thupi, ndipo ndizofanana mofanana.

Chinthu chodziwika kwambiri cha carbimazole ndi Neomercazole.

Neomercazole ndi dzina la carbimazole ndipo amapangidwa ndi Amdipharm International (UK). Mankhwalawa anavomerezedwa mu 2004, ndipo amagulitsidwa ku UK ndi Europe, koma sichipezeka kapena kulamulidwa ku United States. Mukhoza kuona datasheet pa Neomercazole pano. Nazi zina zambiri zokhudzana ndi Neomercazole.

• Webusaiti ya Mankhwala: Amdipharm
• Kufotokozera Information

Neomercazole Zosakaniza : carbimazole Ph.Eur; lactose; starch chimanga; sucrose; magnesium stearate; sucrose; talc; mphukira; ferric oxide; propyl hydroxybenzoate; ndi gelatin.

Mphamvu zopezeka : 5 mg

Maina Ena / Mayina: Carbimazole amapezeka m'mayiko ena a ku Ulaya ndi Asia mwa mayina awa: Atirozidina, Basolest, CG1, Carbimazole Spofa, Carbotiroid, Mertiran, Neo-Mercazole, Neo-Thyreostat, Neo-Tireol, ndi Tyrazol.

Propylthiouracil / PTU

Njira yomwe PTU imachepetsera kutentha kwa kanseri ya hormone ndikuti imaletsa chithokomiro pogwiritsa ntchito ayodini pofuna kutulutsa hormone ya chithokomiro. Zimalepheretsanso kutembenuka kwa toni ya T4 mu T3. PTU ili ndi nthawi yochepa yochita, kotero odwala omwe amamwa mankhwalawa nthawi zambiri amauzidwa kuti amwe mankhwalawa katatu kapena katatu pa tsiku kuti athe kuchepetsa mahomoni a chithokomiro.

PTU imakhala ndi zotsatira zambiri kuposa mankhwala ena omwe atchulidwa pano, ndipo ndi mankhwala omwe amakonda kwambiri a hyperthyroidism pokhapokha pa nthawi zingapo (panthawi yoyembekezera mimba, chiwindi chachikulu cha chithokomiro komanso ngati wodwala akukumana ndi zotsatira zoyipa za methimazole).

Ku United States, PTU yowonjezera imapezeka; palibe maina a PTU ogulitsidwa ku United States. Amapangidwe angapo amapanga PTU yowonjezera.

Zambiri Zambiri

Phunzirani zambiri za hyperthyroidism ndi mankhwala ake, kuphatikizapo antithyroid mankhwala, muzinthu izi:

• Hyperthyroidism | Matenda a Manda. | Chithokomiro choposa
• Matenda a Manda ndi Hyperthyroidism 101

• Hyperthyroidism Kuopsa / Zizindikiro Zowunika
• Matenda a Manda a Manda ndi Hyperthyroidism
• Mafunso Omwe Amadzifunsa Kawirikawiri pa Matenda a Hyperthyroidism ndi Graves
• Njira 3 Zothandizira Hyperthyroidism

_Zotsatira:

_{Daily Med, Database ya US Food and Drug Administration Database, Online}

_{Kulankhulana kwa Drug Safety Drug: Kuchenjezedwa Kwatsopano pa Kuvulala Kwambiri kwa Chiwindi ndi propylthiouracil, pa 21 April 2010, Online}

_{Ross, Douglas MD, "Wodwala mankhwala: mankhwala osokoneza bongo," UpToDate . Idasinthidwa komaliza: November 13, 2009}