Magazini yotchedwa Platelet Volume (MPV) pa Lab Lab Results

Kufunika kwa MPV monga gawo la Complete Blood Count (CBC)

Mwinamwake mwawona makalata "MPV" monga gawo la mayeso anu a Complete Blood Count (CBC) , mayesero omwe amagwiritsidwa ntchito poyesera kuwonetsetsa zaumoyo, komanso pofuna kuchiza matenda ambiri. Mayeso a CBC amayesa maselo ofiira anu (maselo omwe amanyamula oksijeni), maselo oyera a maselo (maselo olimbana ndi matenda), ndi mapuloletsiti (maselo opanga ma clot). MPV (yomwe imatanthauza mapepala a platelet) ndiyeso ya kukula kwa mapuloletsiti (thrombocytes), gawo limodzi mwa magazi anu omwe amathandiza magazi anu kuundana.

Pa CBC yanu mudzakhala ndi lipoti la chiwerengero chanu cha mapepala komanso "zizindikiro za platelet" monga MPV. Mudzazindikira kuti palinso zizindikiro za chiwerengero cha maselo ofiira a magazi ndi kuchuluka kwa maselo oyera. Zizindikirozi zimapereka molongosola molondola mavuto aliwonse ndi maselo anu. Ndipotu, nthawi zina munthu akhoza kukhala ndi maselo amagazi abwino, koma kuwerengera kwa nambala zopanda malire kungamulangize dokotala. MPV ndi yothandiza kwambiri pakuzindikira chifukwa cha thrombocytopenia, chiwerengero chochepa cha platelet, koma chingakhale chithandizo chothandizira ngakhale ngati chiwerengero chanu chaplatelet ndi chachilendo.

N'chifukwa chiyani kukula kwa mapaleletti n'kofunikira, ndipo kumatanthauzanji ngati MPV yanu ilipamwamba kapena yayitali kusiyana ndi yachibadwa? Tiyeni tiwone za zomwe zingayambitse MPV wapamwamba kapena yochepa, komanso momwe MPV ingagwiritsidwire ntchito kulongosola chiopsezo kwa anthu omwe ali ndi matenda ena.

Magazini yotchedwa Platelet Volume (MPV) ndi Health Your

Ma plateti ndi maselo omwe amayenera kupanga mapulasitiki.

Zili zofunika kuti tisatenge magazi kwambiri pamene tadulidwanso komanso kutaya magazi mkati mwa matupi athu. Pamene khungu limatuluka khungu lathu kapena mkati mwa matupi athu, mapaleletti amagwirizana kuti akhululukire dzenje. Zinthu zina zowonongeka (monga zina zomwe sizipezeka mu hemophilia) zimatchedwanso kuti zisawononge magazi.

Mabala a pulasitiki amapangidwa m'mafupa ndi maselo otchedwa megakaryocytes. Ma plateletseni okha ndi zidutswa za megakaryocytes, popanda nuclei, zotulutsidwa m'magazi kuchokera mumtambo. Kawirikawiri, mapiritsi ang'onoang'ono amakhala aakulu kuposa mapulateletti akale.

Makhalidwe Okhazikika a Platelets ndi MPV

Poyang'ana MPV, nkofunika kuyang'ana pa chiwerengero chonse cha mapaleti ndi MPV.

Mtundu wochuluka wa mapalelet (awa akhoza kusiyana pakati pa mabala) ndi 150,000 mpaka 450,000 pa mililita. Kawirikawiri, anthu amatha kulekerera makapu 50,000 ndi kupweteka pang'ono. Mbali yamapiritsi pansipa 20,000, komabe, ikhoza kuika moyo pachiswe. Mapepala a Platelet ndi awa:

• MPV (ikufotokozedwa apa).
• PDW (mapulogalamu apadera ogawa). PDW ikufotokoza kusiyana kwa kukula kwa mapulateletti.

Pofuna kudziwa zomwe zingatheke chifukwa cha MPV yowonongeka, ndikofunika kuyang'ana ngati chiwerengero cha platelet chiri chachilendo, chapamwamba, kapena chapansi.

Zoperewera Poyesedwa / Zolondola za MPV

Chinthu choyamba pamene dokotala akuwona kuti muli ndi MPV wosazolowereka kuti muyesetse kulondola kwa mayesero. Ngati zikuwoneka ngati pangakhale cholakwika ndi kukopa kwa magazi, mayesero adzabwerezedwa.

Kuyezetsa kwa CBC kumafuna magazi osakanizidwa (magazi omwe amalowetsedwa mu chubu yomwe ili ndi anticoagulant kotero kuti magazi sadzatseka) ndipo kawirikawiri amakoka mu chubu chofiirira.

Ngati magazi alowetsedwa mu chubu popanda tizilombo toyambitsa matenda, idzaphimba, kupereka zotsatira zosalongosoka za kuwerengera kwa platelet ndi MPV. Ngati dokotala wanu akukhulupirira kuti kugwidwa kungakhale kochitika, zitsanzo zina zidzatengedwa. Anthu ena amafunika kuti magazi awo alowe mu chubu chosiyana, monga momwe mapulaneti awo amatha kukhalira ndi anticoagulant yomwe imagwiritsidwa ntchito mu chubu chofiirira.

Pamene mtengo wa MPV uli wapamwamba, labu nthawi zambiri amawunika ndi kusiyana kwa magazi, mayeso omwe amawoneka manambala a mitundu yosiyanasiyana ya maselo oyera a magazi. Katswiri wamakono amapanga ndi kutaya magazi anu ndikuyang'anitsitsa pansi pa microscope kuti muone ngati mapuloteni akuphatikizana pamodzi kapena muli ndi mapaleletti akuluakulu.

Izi zikunenedwa, anthu ena ali ndi mapaleti akuluakulu kapena akuluakulu chifukwa cha zifukwa zomwe zili pansipa.

Zifukwa za Platelet Volume High (MPV)

MPV wapamwamba nthawi zambiri ndi chizindikiro choti pali mapiritsi ang'onoang'ono omwe amazungulira m'magazi anu. Ngati mwachitapo kanthu monga opaleshoni yayikulu, thupi lanu likugwiritsa ntchito mapulateletti kuti akonze mdulidwe ku mitsempha ya magazi. Poyankha, fupa lanu la mafupa limatulutsa zina zambiri, mapepala akuluakulu, ndi mapu anu a MPV.

Kufufuza MPV yapamwamba kumathandiza kwambiri pakudziwa chifukwa cha kuchuluka kwa mapuloteni, ndipo chifukwa chofala kwambiri ndi "chiwonongeko," kapena mapulateletti akuwonongedwa mwanjira ina, monga ma antibodies omwe mumabweretsa (onani ITP pansipa).

MPV yapamwamba yokhala ndi mapiritsi apamwamba , mosiyana, kawirikawiri, imakhala chifukwa cha thrombocytosis yoyamba kapena yofunikira (momwe thupi limapangira mapulaneti ambiri, kawirikawiri chifukwa cha kusintha kwa chibadwa), kapena khansara.

MPV yapamwamba yokhala ndi chiwerengero chokhala ndi mapiritsi ambiri imasonyeza zinthu monga hyperthyroidism, kapena matenda aakulu a myelogenous leukemia.

Zinthu zomwe zingayambitse MPV yowonjezera ndi:

• Idiopathic thrombocytopenic purpura (ITP): ITP ndi chikhalidwe chomwe chitetezo cha mthupi chimayesa mbale. Matenda a idiopathic thrombocytopenic purpura ali ndi dzina lautali, koma kuyang'ana pa lirilonse la mawu mu ITP limapangitsa kuti mumvetse mosavuta. Idiopathic ndi mawu omwe amagwiritsidwa ntchito kufotokoza chikhalidwe chosadziwika. Ndi dokotala lingo chifukwa "tilibe chidziwitso" chifukwa chimachitika. Liwu loti "thrombo" limatanthauza clot (ntchito ya mapalelet) ndi "penia" amatanthauza kusowa, choncho thrombocytopenia imatanthawuza kusowa kwa mapuloleteni. Purpura ndilo lingaliro lachipatala chifukwa cha kuvulaza, kawirikawiri kumvunda kwakukulu. (Liwu lakuti petechiae limatanthauzira zizindikiro zofiira phungu (zovulaza zazing'ono) zomwe sizimatsuka pamene mukuziika patsogolo.)
• Magazi a magazi monga khansa ya m'magazi.
• Osakhala chidakwa cha chiwindi matenda.
• Matenda osokoneza bongo m'mapulaneti.
• Matenda a Bernard-Soulier (matenda aakulu a platelet).
• Mankhwala osokoneza bongo, monga erythropoietin kapena thrombopoietin.
• Matenda a shuga.
• Matenda Opuma.
• Sepsis.
• Hyperthyroidism.
• Chiwonongeko cha mtima (onani m'munsimu).
• Pre-eclampsia (toxemia of pregnancy) ndi matenda a HELLP.
• Magetsi a mtima wopangira.

Zifukwa za Platelet Low (MPV)

Zomwe zingayambitse MPV yapamtunda zingakhalenso zosiyana malinga ndi chiwerengero cha platelet. Pulogalamu ya PV yochepa yokhala ndi mtengo wochepa wa platelet ikhoza kutsogoloza zovuta zomwe zimakhudza mafupa omwe amachepetsa kapena kuchepetsa kupanga mapaleti, monga matenda otchedwa aplastic anemia . Ma MPV otsika omwe ali ndi chiwerengero cha mapiritsi ambiri amatanthauza matenda, kutupa, kapena khansa. Mtundu wapansi wa MPV wokhala ndi chiwerengero chokhala ndi mapiritsi ambiri amapezeka ndi matenda aakulu a impso.

Zomwe zingayambitse MPV yochepa ndi izi:

• Kuperewera kwa mafuta a mitsempha (mapaleletti akuluakulu ndi ochepa, kotero MPV ndi yotsika ngati mafupa sakubereka ambiri).
• Splenomegaly (kutambasula kwa mpeni). Pokhala ndi hypersplenism, mapuloletti nthawi zambiri amakhala "otetezedwa" mu ntchentche.
• Kulephera kwa impso
• Mankhwala omwe amalepheretsa kupanga mapuloteni (monga chemotherapy mankhwala).
• Hypothyroidism.
• Kuperewera kwa chuma kwa iron.
• HIV / AIDS.

Kudziwa

Kupezeka kwa MPV yapamwamba kapena yochepa kumadalira zinthu zambiri kuphatikizapo kuchuluka kwa mapulogalamu, maselo ofiira a magazi, ndi maselo oyera a magazi. Kuyezetsa mongofu kungafunikire ngati pali nkhawa yokhudzana ndi mafupa osagwira ntchito kapena kuti kansa ikhoza kukhalapo. Izi zanenedwa kuti, kuyesa kungakhale kosavuta ngati kuyang'ana mayeso a chithokomiro.

Wapamwamba MPV, Heart Disease, ndi Stroke

Zaka zaposachedwapa zakhala zikupezeka kuti MPV ikhoza kuthandizira pa matenda oyambirira a mtima. Kafukufukuyu ndi wamng'ono, koma akuganiza kuti MPV wapamwamba akhoza kufotokozera chiopsezo kuti munthu amene ali ndi matenda a mtima adzakhala ndi matenda a mtima, ndipo amaneneratu kuti anthu omwe ali ndi matenda opatsirana pogwiritsa ntchito matenda a mtima amakhala odwala. Mofananamo, MPV yakwezeka ingakhale yowonongeka, komanso imapereka chithunzithunzi kwa iwo omwe angachite mofulumira. Kafukufuku akuyang'anitsitsa kuti aone ngati MPV yakwezeka ingakhale ndi mbali iliyonse poyesa chiopsezo cha mitsempha ya magazi (deep vein thrombosis ndi pulmonary emboli), komanso matenda opatsirana ammimba.

MPV Monga Chizindikiro cha Kugonjetsa

Kuwonjezera pa zomwe zingatheke kulosera zotsatira za matenda a mtima ndi kupwetekedwa mtima, kafukufuku apeza kuti MPV ikhoza kukhala ndi nthawi yowonongeka pamatenda monga chifuwa cha khansa ya m'mawere, poyerekeza ndi khansa ya m'mawere kuchokera ku khansa ya m'mimba. , komanso pozindikira kuti thupi limakhala lopweteka kwambiri.

Pulogalamu Yofunika Kwambiri ya Platelet

Kutanthauza mapuloteni voliyumu (MPV) ndiyeso ya kukula kwa mapuloletsiti ndipo amatha kugwira ntchito yofunikira kuti apeze matenda ngati chiwerengero cha platelet chiri chapamwamba, chochepa, kapena chachibadwa. Kuwonjezera pa kuyezetsa matenda, timaphunzira kuti MPV ikhoza kukwanitsa kugwira ntchito monga matenda a mtima, ndipo ngati zili choncho, akhoza kutsogolera madokotala kuti adziwe kuti anthu akutsatidwa kwambiri kapena kulandira zamwano mankhwala.

> Zotsatira:

> Fixter, K., Rabbolini, D., Valecha, B. ndi al. Njira Zowonjezerapo za Platelet Zopangira Thrombocytopenias Cholowa. International Journal of Laboratory Hematology . 2017 Nov 16. (Epub patsogolo pa kusindikiza).

Kasper, Dennis L .., Anthony S. Fauci, ndi Stephen L .. Hauser. Mfundo za Harrison za Mankhwala a M'kati. New York: maphunziro a Mc Graw Hill, 2015. Print.

> Mtsogoleri, A., Pereg, D., ndi M. Lishner. Kodi Ndondomeko ya Mapulogalamu a Platelet of Clinical Use? Ndemanga ya Multidisciplinary. Annals of Medicine . 2012. 44 (8): 805-16.

> Noris, P., Melazzini, F., ndi C. Balduini. Ntchito Zatsopano Zopangira Platelet Powonongeka Pomwe Momwe Mungagwiritsire Ntchito Pachipatala? . Platelets . 2016. 27 (7): 607-612.