Ngati inu kapena wokondedwa wanu muli ndi MS wopita patsogolo , mungakhale oda nkhawa kapena okhumudwa kuti palibe mankhwala ovomerezeka a mtundu wanu wa matenda. Koma zitsimikizirani kuti, ofufuza akugwira ntchito mwakhama, ndipo akuchiritsira akuyamba.
Njira imodzi yotereyi ndi mavitamini biotin. Tiyeni tiwone bwinobwino kafukufuku wa sayansi yemwe amachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda.
Zotsatira za MS vs. Kubwezeretsanso-kukumbukira MS
Ngakhale kuti anthu ambiri omwe ali ndi multiple sclerosis amatha kubwezeretsa MS (pafupifupi 85 peresenti), kachigawo kakang'ono (pafupifupi 10 mpaka 15 peresenti) ali ndi MS apamwamba kwambiri. Izi zikutanthauza kuti iwo sakhala ndi chizoloŵezi choyambiranso bwino cha matenda osokoneza ubongo.
Biology pambuyo pa kubwezeretsedwa kwa MS ndiko kuti chitetezo cha mthupi cha munthu chimagonjetsa chitetezo cha myelin. Mwa kuyankhula kwina, kubwereranso ndi njira yotupa yotupa. Koma mu MS yomwe ikupita patsogolo, njira yowonjezera yotupa komanso yowonjezereka imapezeka, pomwe mitsempha ya mitsempha imayamba kuchepa. Kotero munthu yemwe ali ndi MS akupitirizabe kuwonjezereka kuwonongeka kwa ubongo wa mphuno popanda nthawi za kukhululukidwa.
Mawu akuti MS omwe amapitabe patsogolo akufotokozera munthu yemwe adayamba kubweranso, koma tsopano wasintha njira yopita patsogolo ya MS. Anthu ambiri omwe ali ndi MS obwezeretsa kachiwiri amatha kusintha kupita ku MS wachiwiri.
Ngakhale, izi zingasinthe ndi kugwiritsa ntchito mankhwala ochiritsira oyambirira.
Biotin monga Thandizo Labwino
Popeza kuti mankhwala omwe amachititsa kuti chitetezo cha mthupi cha munthu chitetezedwe sichigwira bwino ntchito yochizira MS (kupatula ngati munthu akuyambiranso kubwereza), ofufuza akhala akuyesera kupeza mankhwala omwe angapangitse chitsanzo cha multiple sclerosis.
Mwa kuyankhula kwina, mankhwala omwe amamenyana ndi machitidwe a mitsempha aakulu osati mawonekedwe a chitetezo cha mthupi.
Kwa ochita kafukufuku, vitamini biotin imawoneka ngati njira yabwino, poyesa kuti yapezeka kuti imatha kuchiza matenda enaake oopsa a m'mitsempha yapamwamba kwambiri. Sayansi, kodi biotin ingathandize bwanji MS kupititsa patsogolo kwa munthu? Biotin amathandizira kupanga mavitamini amtundu m'thupi, ndipo chida cha myelin ndi chophimba. Choncho, asayansi amanena kuti biotin ikhoza kuyambitsa kusakaniza kwa mafuta acids, omwe angapangitse kuti ndisamangidwe komanso kutetezedwa ku chiwonongeko cha mitsempha ndi kutayika.
Kafukufuku Wotsatira Biotin
Phunziro loyambirira lomwe linaphunzirira kupatsa MS patsogolo ndi biotin ndi kuphunzira kwa French ku Multiple Sclerosis ndi Related Disorders . Phunziro ili, anthu 23 omwe ali ndipakati pazaka 14 (14) kapena MS omwe amapita patsogolo (anthu asanu ndi anayi) adapatsidwa mlingo wa biotin tsiku lililonse (100mg kufika 600mg) kwa miyezi pafupifupi 9.
Zotsatira za phunziroli zinaulula izi:
- Anthu anayi adasowa masomphenya achilendo ochokera ku MS-optic nerve matenda musanaphunzire. Onse anali ndi maonekedwe abwino owonetsetsa bwino ndi biotin yapamwamba (300mg / tsiku).
- Munthu m'modzi adali ndi dzina lamanzere la munthu wotchedwa Hemianopia asanayambe kuphunzira (kutanthauza kuti mbali ya kumanzere kwa diso lililonse sinali bwino). Munthuyu anali ndi masomphenya, ngakhale kuti vuto lachilendo ku ubongo wake la MRI linali losasinthika.
- Anthu 18 ali ndi mimba ya msana asanayambe kuphunzira-11 anthu omwe ali ndi ziwalo zoopsa zowonjezereka (zowonongeka kapena zowonongeka kwa miyendo inayi) komanso anthu asanu ndi awiri omwe ali ndi paraparesis (kupunduka pang'ono kapena kwathunthu kwa miyendo iwiri). Anthu khumi ndi atatu (18) mwa iwo (89 peresenti) anali atakula (pakuchitika miyezi iwiri kapena eyiti pambuyo pa mankhwala a biotin anayamba).
Mwa iwo amene anakula (zomwe zinayesedwa ndi katswiri wochititsidwa khungu akuwonera mavidiyo a kanema wa kafukufuku wothandizira), kusintha kwakukulu kunayesedwa ndi mlingo waukulu wa biotin, pa 300mg / tsiku.
Zizindikiro zina zokhudzana ndi MS zowonongeka zomwe zikuphatikizapo:
- kutopa (anthu asanu)
- kumeza mavuto (anthu anayi)
- kulankhula mofulumira kapena kosasunthika (anthu atatu)
- zizindikiro zosonyeza (anthu awiri)
- kuyenda mosagwirizana-kutchedwa gait ataxia (anthu awiri)
Potsirizira pake, kulemala, monga kuyesedwa ndi chiwerengero cha EDSS , kunakula mwa anthu anayi (23 peresenti).
Zotsatira zovuta zokha zomwe zinaperekedwa mu phunziroli zinali kutsekula m'mimba mwa anthu awiri. Munthu mmodzi anafa chifukwa cha kufooka kwa mtima patatha zaka zitatu atayamba mankhwala a biotin ndipo patapita chaka chimodzi, munthu anamwalira ndi chibayo atachita opaleshoni yam'kati. Zitsanzo ziwiri za imfa sizinali zogwirizana kuti zikugwirizana ndi mankhwala ndi biotin.
Komanso, kumbukirani kuti anthu omwe ali ndi MS akupitirizabe kubwereranso nthawi zina. Phunziroli, anthu anayi (13 peresenti) adakumana ndi kachilombo kakang'ono kamodzi ka MS. Koma malinga ndi ochita kafukufuku, nambala iyi inali yofanana ndi zomwe zimawonedwa mwa anthuwa musanayambe mankhwala ndi biotin. Mwa kuyankhula kwina, biotin sanawoneke molakwika kapena mobwerezabwereza kumakhudza zochitika za MS kachiwiri.
Phunziro lina la Biotin lochiza MS patsogolo
Phunziro lina lachifalansa la Multiple Sclerosis , anthu omwe ali ndi MS oyambirira kapena apamwamba omwe amawunikira amadziwika kuti alandira 100mg biotin kapena placebo (mapiritsi amayang'ana ndikulawa chimodzimodzi) tsiku ndi tsiku (pafupifupi 300mg biotin tsiku lililonse, ngati si placebo ).
Ophunzirawo kapena ofufuza omwe anafufuza adadziwa kuti adalandira mapiritsi a biotin ndipo adalandira mapiritsi a placebo. Izi zinachitika kwa chaka chimodzi (chotchedwa gawo loyamba). Pamapeto pake, anthu 91 adalandira mapiritsi a biotin ndipo anthu 42 adalandira mapiritsi a placebo.
Kenaka kwa chaka china, onse omwe adagwira nawo ntchito (kuphatikizapo olowa nawo pa placebo) adalandira 100mg biotin katatu tsiku ndi tsiku (kutchedwa extension extension). Iwo sankadziwa ngati iwo analandira biotin chaka choyamba kapena placebo.
Zotsatira zake zasonyeza kuti 13 (12,6 peresenti) ya omwe anachitapo kanthu ndi biotin kuyambira pachiyambi anali ndi kuchepa kwaumphawi wawo wokhudzana ndi MS, ndipo khumi mwa khumi ndi atatuwa 13 adapitiliza kukonzanso pomaliza maphunziro (miyezi 24). Anthu awiri omwe analandira biotin m'gawo loyamba sanawonetsere bwino m'miyezi 12 yoyambirira koma anachita mapeto a miyezi 24.
Kukula kwaumalema kunayesedwa pang'onopang'ono mu chiwerengero cha EDSS ndi / kapena kuchepetsa nthawi yomwe amayenda kuyenda mamita 25. Wotsatsa apa ndikuti panalibe kusintha kwa gulu la placebo, kutanthauza kuti biotin inakhala ndi zotsatira zabwino. Komanso, mofanana ndi phunziro loyambirira lomwe latchulidwa, biotin inalekereredwa bwino, popanda zotsatira zoopsa.
Zonsezi zikunenedwa, ponena za vuto lomwe olemba owerenga amaphunzira ndi lakuti omwe adalandira biotin anali ndi zilonda zamakono kapena zofutukula za ubongo (monga momwe zikuwonedwera pa MRI) kuposa omwe ali mu gulu la placebo. Ndiye funso likubwera ngati biotin ikuyambitsa kubwezeretsa poyambitsa chitetezo cha mthupi cha munthu? Ichi ndi chifukwa chake kufufuza kwakukulu kumafunikira.
Mawu Ochokera
Kodi maphunzirowa akusonyeza chiyani? Amanena kuti biotin ikhoza kuthandizira kusintha kwaumphawi kwa anthu omwe ali ndi MS oyambirira kapena apamwamba. Ngakhale zili choncho, kufufuza kwakukulu komanso kozama kumafunika kuti zisanachitike. Mwachitsanzo, zingakhale bwino kuyang'ana zilonda za ubongo pa MRIs mu maphunziro amtsogolo.
Komanso, kafukufuku wofufuzira amasonyeza kuti biotin ikhoza kukhala yothandiza kuchiritsa kuona bwino, zomwe zimapangitsa akatswiri kuti aziwombera mitu yawo pang'ono. Pafupipafupi, pakufunika maphunziro akuluakulu kuti athetse phindu lenileni la biotin mu multiple sclerosis. Izi ndizovuta, ndipo pamene mukudya nthawi, zimakhala zabwino kwambiri kwa inu kapena mnzanuyo.
> Zotsatira:
> National MS Society. Mafunso Ofunsidwa Kawirikawiri Za SPMS.
> Sedel F et al. Mankhwala apamwamba a biotin mu matenda osapitirira ambiri a m'mimba: kuphunzira kwa woyendetsa. Kusokonezeka kwa Mbale Scler Relat . 2015 Mar 4 (2): 159-69.
> Tourbah A et al. MD1003 (high-dose biotin) pochizira matenda opitirira maulendo ambiri: Kuphunzira kosawerengeka, kawiri khungu, kopanda malo. Mult Scler. 2016 Nov; 22 (13): 1719-31.