Mungathe Kutenga Estrogen Ndi Khansa ya M'mimba
Kwa zaka zambiri, amayi ndi madokotala awo akuda nkhaŵa kuti kutenga estrogen kungapangitse khansa ya m'mawere. Ndinafotokozera mwachidule chifukwa chake izi sizinali choncho posakhalitsa kuti ndifalitsidwe buku, The Estrogen Window, ndi momwe estrogen, yotengedwa m'ndandanda ya estrogen, imachepetsa chiopsezo cha khansa ya m'mawere. Komabe, kuopa kutenga estrogen kwakhala kochuluka kwambiri moti amayi omwe ali kale ndi khansa ya m'mawere samamvetsetsa mtundu uliwonse wa estrogen kuphatikizapo vaginitis.
Izi zakhala zovuta makamaka kwa amayi omwe ali ndi kansa ya m'mawere. Kuwonjezera pa kusintha kwa thupi komwe kumachitika chifukwa cha kuchotsedwa kwa khansa kapena nthawi zambiri, bere, palinso zizindikiro za kusamba kwa mimba. Nkhani yabwino ndi yakuti zinthu zakuthupi zingathe kuthandizidwa ndi opaleshoni yokonza komanso popanda njira yabwino yothetsera vutoli.
Komabe, zizindikiro za kusamba kwa thupi zakhala zovuta kwambiri kuti zithetse popeza estrogen ndi mankhwala othandiza kwambiri. Pakhala mankhwala awiri atsopano omwe si a-estrogen omwe amavomerezedwa kuti athetsere zizindikiro za kusamba. Mafuta otentha (Brisdelle) ndi owuma (Osphena), koma kuuma kwa ubenda ndi kugonana kowawa kumakhalabe nkhani zazikulu kwa amayi ambiri amatha kuchiza khansa ya m'mawere.
Tsopano pali lipoti losintha masewera lofalitsidwa ndi American College of Obstetricians ndi Gynecologists (ACOG).
Mfundo Yatsopano ya Komiti yochokera ku American College of Obstetricians ndi Gynecologists (Namba 659, March 2016) imati ACOG imakhulupirira kuti pali umboni wokwanira kunena kuti zili bwino (kugwira ntchito ndi oncologist) kwa amayi omwe ali ndi kansa ya m'mawere yogonana ndi estrogen . Ngakhale estrogen imalowa m'magazi, sizikuwoneka kuti zimakhudza zotsatira.
Magazi a magazi samapitirira kuposa momwe magulu ambiri a magazi a estrogen aliri pakusamba kwake.
Ndipo pali umboni woti uyambe kumbuyo. Kaya mukudwala khansa ya m'mawere, mwakhala mukuchiritsidwa kale ndi khansa ya m'mawere, ndipo ngakhale mutatenga Tamoxifen, yomwe ndi anti-estrogen, zotsatira za kugwiritsira ntchito vaginomu ndizosiyana ndi zomwe simukuzichita. tengani. Ndimayankhula za izi ndi mfundo zofunika zokhudzana ndi estrogen m'buku langa latsopano, The Estrogen Window.
Izi ndi zazikulu kwa amayi chifukwa khansara ya m'mawere ndi khansa yowopsa kwambiri pakati pa mafuko onse. Ndichonso chimayambitsa matenda a khansa pakati pa a Hispanics. Ku United States, khansa ya m'mawere imakhudza akazi amodzi mwa asanu ndi atatu ndipo pakalipano pali amayi oposa 2 miliyoni a ku United States omwe apatsidwa chithandizo cha khansa ya m'mawere.
Pali mitundu yosiyanasiyana ya vaginitis:
| Zimaperekedwa bwanji | Kodi Muli Chiyani? | Zimatengedwa bwanji |
| Cream Yamagazi | 17 beta estradiol | Kawirikawiri 1-2 magalamu tsiku lililonse kwa masabata 1-2, ndiye 1 gramu 1-3 nthawi / sabata |
| Cream Yamagazi | Anagwedeza equine estrogen | Pang'onopang'ono makilogalamu 0,5 kwa masiku 21 amachoka masiku asanu ndi awiri, kapena kawiri mlungu uliwonse ngati osakhala ochepa |
| Mphuno Yamagetsi | 17 beta estradiol | Mphindi 2-mg kumasula 7.5 micrograms / tsiku kwa masiku 90 |
| Vaginal Tablet | Estradiol hemihydrate | Piritsi imodzi ya microgram / tsiku kwa milungu iwiri kenako pulogalamu imodzi ya microgram piritsi / tsiku 2-3 nthawi / sabata |
Mankhwala ambiri omwe amagwiritsidwa ntchito pa khansa ya m'mawere ndi mbali imodzi mwa kuthetsa kapena kutchinga zochitika zonse za estrogen. Chotsatira chake, amayi omwe ali ndi chizoloŵezi cha kumaliseche amatha msinkhu kuti ayambe kusamba ndipo amayi omwe ali kale kumaliseche omwe tsopano ali ndi m'mimba otsika a estrogen amapatsidwa mankhwala ochiza matenda omwe amachititsa maere awo otsika ndi otsika.
Chimodzi mwa zotsatira zoipitsitsa za kukhala ndi estrogen ndi kuyanika kwaumayi, kupatulira kwa mazira ndi chikhodzodzo chotchedwa atrophic vaginitis. Mawu atsopano a zamankhwala pa izi ndi Genitourinary Syndrome of Menopause (GSM) yomwe imayambitsa kugonana kowawa ndipo nthawi zina imatsutsa maubwenzi.
Izi ndizosintha kwambiri masewera kwa amayi omwe ali ndi khansa ya m'mawere. Ngakhale kuti ndakhala ndikupereka maantirojeni kumaliseche kwa odwala khansa kwa zaka zambiri, ambiri adakana chithandizo chifukwa awo oncologists adanena kuti asatenge ndipo akhala omveka bwino. Khansara ya m'mimba ndekha ndi yoipa. Ndipo ngakhale mankhwala osachiritsika ali okwanira kuti athe kuchiza zizindikiro za GSM kwa ena, palibe kukayika kuti amayi ambiri amapindula ndi kugwiritsidwa ntchito kwa vaginisitrogeni; Ndi njira yabwino kwambiri yothetsera zizindikiro za GSM. Tsopano estrogen idzakhala njira yoyenera kwa amayi ambiri omwe ali ndi khansa ya m'mawere.