Momwe HIV imakhalira, Momwe Mumakhalira, Mmene Mumatetezera Mthupi, ndipo DNA Yanu Imakhudzana
Palibe amene amadziwa chomwe chimayambitsa matenda ambiri a sclerosis (MS). Izi zanenedwa, zifukwa zinayi zikuluzikulu zakhala zikuyesa kufotokoza chifukwa chake anthu ena amapanga MS ndipo ena samatero. Ngakhale chimodzi mwazifukwazi zingathe kufotokozera gawo la MS puzzle, palibe amene angathe kufotokoza chirichonse. Zifukwa zinayi izi ndi izi:
- chitetezo cha mthupi
- chilengedwe
- matenda opatsirana
- zojambula
Chitetezo cha Immune ndi MS
Ngakhale palibe amene amadziwa chifukwa chake, ambiri ofufuza amavomereza kuti MS imayambitsidwa ndi chitetezo cha mthupi choukira thupi. Makamaka maselo a chitetezo cha thupi amateteza maselo mu ubongo ndi msana , kuwononga mzere wamkati (myelin) wamatope. Kuwonongeka kumapangitsa kuti mitsemphayo ikhale yogwira bwino-gwero la MS zizindikiro ndi kulemala. Mankhwala opangidwa ndi matenda amagwira ntchito pogwiritsa ntchito njira zosiyana zothandizira chitetezo cha thupi kuti chiteteze dongosolo la mitsempha.
Chilengedwe ndi MS
Anthu m'madera ndi madera ena ali ndi chiopsezo chachikulu kwa MS kuposa ena. Powerenga anthu omwe amachoka kudera lina kupita kumalo ena, ofufuza aphunzira kuti kusintha kwachangu kumadalira malo.
Ndipotu, MS imapezeka zambiri m'madera akutali ku equator. Ofufuza ambiri amakhulupirira kuti vitamini D ikhoza kufotokozera zochitika izi. Vitamini D imapangidwa ndi thupi pamene khungu limakhala ndi dzuwa.
Kumadera akutali ndi equator, mlengalenga imasungunula mazira a dzuwa omwe amachepetsa mavitamini D opanga thupi.
Kafukufuku watsopano akusonyeza kuti mavitamini D apamwamba angateteze munthu kuti asapange MS, ndipo amateteze munthu yemwe ali ndi MS kuti abwererenso.
Palinso zinthu zina zachilengedwe zomwe asayansi anazifufuza ngati zowonongeka za MS kuphatikizapo:
- Kusuta
- zakudya zamchere zam'mwamba
- kunenepa kwambiri (makamaka paunyamata)
Matenda ndi MS
Mavairasi ena amadziwika kuti amawononga zofanana ndi zomwe zimawonedwa mu MS. Akatswiri ena amakhulupirira kuti matenda ena amachititsa kuti chitetezo cha mthupi chiteteze maselo a mitsempha. Kwenikweni, kachilombo (kapena mabakiteriya) omwe amachititsa matenda oyambirira "amayang'ana" ngati selo la mitsempha. Chitetezo cha mthupi chimayambitsa T-maselo kuti amenyane nawo. Ma T-maselowo amakhalabe m'thupi mwathu mutatha kale matendawa atasokonezeka pamene "awone" maselo a mitsempha, akuyesa kuti ndi othawa. Zotsatira zake ndikuti chitetezo chanu cha mthupi chimasokoneza dongosolo lanu la mitsempha.
Vuto limodzi lomwe limagwirizanitsidwa ndi MS ndi kachilombo ka Epstein-Barr-komwe kumayambitsa "mono." Iyi ndi kachilombo kawirikawiri komwe imakhudza anthu ambiri panthawi ina. Kutanganidwa koyambirira kwa kachirombo ka HIV kungathandize kwambiri pakukula kwa MS, koma akatswiri samadziwa kwenikweni pa nthawi ino.
Panthawiyi, palibe matenda opatsirana (kachilombo, mabakiteriya, kapena bowa) atapezeka kuti akuyambitsa MS.
DNA yanu ndi MS
Ochita kafukufuku amakhulupirira kuti maselo ena amtunduwu amachititsa kuti munthu apange MS. Ndipotu, asayansi atulukira mitundu yambiri ya majeremusi yomwe imawoneka kuti ikugwirizana ndi MS, yomwe ili pafupi ndi majini omwe amagwirizana ndi chitetezo cha munthu.
Kuphatikiza pa kukhala ndi MS, ndizotheka kuti majini anu amatha kufotokozera mtundu wa MS womwe muli nawo, momwe matenda anu alili, komanso ngati mumayankha bwino mankhwala omwe ali ndi matenda a MS.
Izi zikunenedwa, ndizofunika kumvetsetsa kuti MS si "matenda a chibadwa" -kutsutsa kuti palibe jini limodzi lobadwa kapena magawo a jini omwe apezeka omwe akusonyeza kuti munthu atha kupeza MS. Mmalo mwake, zikuwoneka kuti majini ndi chinthu chimodzi, mwa ambiri, chomwe chimatsimikizira kuti munthu ali ndi chiopsezo cha MS.
Zomwe mungachite kuti mukhale ndi MS zikuwonjezeka ngati muli ndi wachibale ndi MS-chidziwitso china chomwe chibadwa chimathandiza pakukula kwa MS.
Mwayi wokhala ndi MS muli pafupifupi:
- 1 mwa 750 ngati mulibe achibale a MS
- 1 mwa 50 ngati muli ndi kholo la MS
- 1 pa 20 ngati muli ndi mchimwene ndi MS
- 1 mwa 4 ngati mapasa anu ofanana ali ndi MS
Zotsatira:
Birnbaum, MD George. (2013). Multiple Sclerosis: Buku la Clinician la Kufufuza ndi Chithandizo, 2 Edition. New York, New York. Oxford University Press.
Gourraud PA, Harbo HF, Hauser SL, & Baranzini SE. Genetics of Multiple Sclerosis: Kukambitsirana Kwatsopano. Immunol Rev. 2012 Jul; 248 (1): 87-103.
National Institute of Neurological Disorders ndi Stroke. Multiple Sclerosis: Chiyembekezo Kupyolera Mufufuza.
Salzer J et al. Vitamini D monga Chowongolera mu Multiple Sclerosis. atsogoleri. Neurol. 2012 Nov 20; 79 (12): 2140-5.