Zindikirani Izi Kuyanjana kwa mankhwala a Statin

Lankhulani ndi dokotala wanu za mankhwala onse

Ma Statins amalembedwa kuti achepetse mitsempha ya cholesterol. Komabe, amakhalanso ndi mwayi wothandizana ndi mankhwala, kuphatikizapo mankhwala ambiri omwe amagwiritsidwa ntchito kwambiri pa mankhwala komanso mankhwala owonjezera. Statins iyeneranso kupeŵedwa ndi anthu omwe ali ndi matenda ena kapena kungogwiritsidwa ntchito mosamala.

Pazifukwa izi, ndizofunika kuti mukambirane mbiri yanu yachipatala ndi zonse zomwe mukuchita ndi dokotala wanu.

Statins Si Onse

Statins ndi gulu la mankhwala osokoneza mafuta m'thupi omwe amakhudza mbali zonse za mbiri yanu. Amatha kuchepetsa cholesterol cha LDL (cholesterol "choipa") ndi triglycerides popatsa cholesterol cha HDL ("chabwino").

Ngakhale kuti amachepetsa kwambiri mafuta m'thupi, zilembo sizingakhale za aliyense. Palinso zinthu zina zomwe muyenera kuletsa wothandizira zaumoyo wanu musanayambe mankhwala a statin.

Izi zikuphatikizapo matenda aliwonse amene mungakhale nawo kapena mankhwala omwe mukuwutenga. Mankhwala samangoperekedwa kwa omwe adakulamulirani ndi dokotala wina koma amaphatikizapo pa-counter-a-counter (OTC) ndi zakudya kapena zowonjezera zowonjezera mankhwala.

Kuonjezerapo, ngati mutalandira chithandizo chamankhwala kuchokera kwa munthu wina kupatulapo wothandizira zaumoyo wanu, mulole kuti munthuyo adziwe kuti mukutsatira malamulo.

Zochitika Zamankhwala Zofunika Kulipoti

Lolani wothandizira zaumoyo wanu kuti adziwe ngati muli ndi chimodzi kapena zingapo zomwe zikukukhudzani musanayambe kutenga statin:

• Matenda a Chiwindi: Kaya akugwira ntchito kapena ayi.
• Mimba: Zolemba zimayambitsa zilema zobereka.
• Kuyamwitsa: Mankhwala a Statin akhoza kuwoloka mkaka wa m'mawere ndikukamwa ndi mwana wanu.
• Kuledzeretsa Mowa: Ma Statins amatha kuonjezera mavitamini a chiwindi.

Kuyanjana Koyenera Mankhwala

Mankhwala ena angagwirizane ndi statins mwa kuchepetsa kupambana kwa statin kapena kuonjezera chiwerengero cha statin m'magazi mpaka pamene chingakhale chovulaza thupi.

Onetsetsani kuti mumauza chithandizo chako chaumoyo ngati mutenga kale mankhwala aliwonsewa pansipa.

Chifukwa chakuti muli pamodzi mwa mankhwalawa, sizikutanthauza kuti simungathe kutenga chikhalidwe. Komabe, wothandizira zaumoyo wanu angafunike kukuyang'anani mwatcheru panthawi iliyonse ya izi chifukwa akhoza kuonjezera chiopsezo chanu.

Kumbukirani kuti iyi si mndandanda wathunthu ndipo muyenera kufunsa wothandizira zaumoyo wanu kuti mudziwe zambiri. Mufunanso kutchula mfundo za statin ngati mukufuna Crestor (rosuvastatin), Zocor ( simvastatin ), Mevacor (lovastatin), Lescol (fluvastatin), Lipitor ( atorvastatin ), kapena pravachol (pravastatin).

Uwu ndiwo mndandanda wa mankhwala ndi mankhwala omwe muyenera kudziwa:

• Nicotinic acid , kapena niacin, pa mlingo waukulu (oposa 1 gram pa tsiku) ikhoza kuonjezera chiopsezo chokumana ndi zowawa za statin.
• Zomwe zimayambitsa ma acid amachepetsa mphamvu za statins ena. Pofuna kupewa izi, zingakhale zolimbikitsidwa kuti mulekanitse mankhwala anu a statin ndi bile acid sequestrant mlingo kwa maola anayi.
• Mafuta amatha kuonjezera chiopsezo chokhala ndi zotsatira za chikhalidwe.
• Mchenga kapena Neoral (cyclosporine) ukhoza kuonjezera chiwerengero cha zilembo zomwe zilipo m'magazi ndipo zingawonjezere zotsatirapo.

• Fluvoxamine ingapangitse kuchuluka kwa ziwalo zina zomwe ziri m'magazi ndipo zingakhalenso kuonjezera zotsatira za statin.
• Mankhwala osokoneza bongo omwe amathera "-azole", monga Nizoral (ketoconazole), Diflucan (fluconazole), Mycelex (miconazole), kapena Sporanox (itraconazole), akhoza kuwonjezera kuchuluka kwa ma statins omwe ali m'magazi komanso angapangitse zotsatira za statin .
• Mankhwala oletsa antibiotic omwe amatha "-mycin" monga erythromycin kapena Biaxin (clarithromycin) angawonjezere maimidwe omwe alipo m'magazi ndipo angapangitse zotsatirapo.
• Mankhwala opatsirana kwambiri a magazi, monga diltiazem ndi verapamil, akhoza kuwonjezera maimidwe omwe alipo m'magazi ndipo akhoza kuonjezera zotsatira.

• Cordarone (amiodarone) ingapangitse kuchuluka kwa zilembo zina zomwe ziri m'magazi ndipo zingakhalenso kuonjezera zotsatira za zilembo.
• Matenda a HIV Protease, monga Norvir (ritonavir), Agenerase (amprenavir), Crixivan (indinavir), kapena Viracept (nelfinavir), amatha kuchulukitsa kuchuluka kwa ziwalo zina zomwe zimapezeka m'magazi ndipo zingawonjezere zotsatirapo.
• Coumadin (warfarin) pamodzi ndi statin ikhoza kuchepetsa mphamvu ya magazi yophimba.
• Prilosec (omeprazole) akhoza kuonjezera kuchuluka kwa zilembo zina zomwe ziri m'magazi ndipo zingathenso kuonjezera zotsatira za zilembo.
• Tagamet (cimetidine) ingapangitse kuchuluka kwa zilembo zina zomwe zili m'magazi ndipo zingakhalenso kuonjezera zotsatira za zilembo.
• Zantac (ranitidine) zingawonjezere kuchuluka kwa zilembo zina zomwe ziri m'magazi ndipo zingakhalenso kuonjezera zotsatira za zilembo.
• Mankhwala ovomerezeka a pamlomo ndi maimidwe omwe amachitidwa panthawi imodzi angathe kuwonjezera mahomoni ambiri m'thupi.
• Lanoxin (digoxin) ingapangitse kuchuluka kwa maonekedwe ena mu thupi.
• Antacids okhala ndi magnesium kapena aluminium hydroxide angachepetse chiwerengero cha ma statins m'thupi. Izi zikhoza kutetezedwa ndi kulekanitsa mlingo wanu wa dozi ndi mlingo wa mankhwala osapatsirana mwa maola awiri osachepera.
• Wotchedwa St. John's Wort angachepetse mphamvu za statins ena.

Mawu Ochokera

Ngakhale kuti statins ikhoza kukhala yopindulitsa kuchepetsa cholesterol ndi kuchepetsa chiopsezo cha matenda a mtima, mukhoza kuona kuti pali zowonongeka zoti ziganizidwe. Izi ndi zochepa zokha zothandizana ndi mankhwala, chifukwa chake ndi kofunika kuti mukambirane mbiri yanu yachipatala ndi mankhwala onse-mankhwala kapena ayi-ndi gulu lanu lachipatala musanatenge chikhalidwe.

> Zotsatira:

> Dipiro JT, Talbert RL. Pharmacotherapy: Njira ya Pathophysiologic. 10th ed. New York, NY: Maphunziro a McGraw-Hill. 2017.

> Lacy CF, Armstrong LL, Goldman MP, et al. Lexicomp's Drug Information Handbook. 26th ed. Hudson, OH: Lexi-Comp Inc.; 2017.