Melatonin ndi momwe zingathandizire ndi kugona ndi kugulitsa masoka mu Alzheimer's
Matenda a Alzheimers ndi matenda oopsa, koma mankhwala osiyana ndi a hormonone a melatonin amatha kuwongolera zizindikiro zovuta monga kusowa tulo komanso kutentha.
Alzheimer's ndi Melatonin
Melatonin ali ndi maudindo ambiri m'thupi, koma ndi ofunika kwambiri mu lamulo la kugona. Melatonin imapangidwa mu ubongo ndi pineal gland. Mtundu uwu umatulutsa chiwerengero chake cha melatonin madzulo, ndipo mahomoni amawoneka ngati othandiza pa kusintha kwa kusintha komwe timati timagona.
Kafukufuku wakhala atakhazikitsidwa kale kuti ma melatonin amatha kuchepa ndi zaka, koma anthu omwe ali ndi matenda a Alzheimers amakhala otsika kwambiri - nthawi zina ndi theka kwambiri ngati anthu a msinkhu womwewo omwe alibe matendawa. Ndiponso, kusokonezeka kugona kawirikawiri ndi chizindikiro cha Alzheimer's. Zaka zaposachedwapa, kafukufuku wambiri wanena kuti amapindula ndi melatonin yowonjezerapo, osati kuchepetsa mavuto okhudza kugona kwa Alzheimer, koma chifukwa cha kugwa kwa dzuwa.
Sundowning imatanthauzanso kusokonezeka kwa makhalidwe omwe ali ofala mu matenda a Alzheimer ndipo amayamba kuchitika madzulo. Pazifukwa zomwe siziri zomveka bwino, anthu ambiri omwe ali ndi chiwonetsero cha Alzheimer anawonjezereka chisokonezo , nkhawa , kusokonezeka komanso kuzunzidwa kumapeto kwa tsiku. Malingana ndi Alzheimer's Association, pafupifupi munthu mmodzi pa asanu mwa anthu omwe ali ndi matenda a Alzheimer adzakhala ndi nthawi yowonongeka, kawirikawiri m'katikati mwa matendawa.
Sundowning imabweretsa mavuto kwa iwo omwe ali ndi Alzheimer ndipo amathandiza kwambiri kusamalira nkhawa ndi kutopa. Mwamwayi, pali umboni wosonyeza kuti melatonin ingathandize pakagwa dzuwa komanso kusokonezeka komweku.
Ubwino Wina wa Melatonin mu Alzheimer's
Melatonin ingakhalenso ndi phindu lina. Ndi antioxidant amphamvu, yochitapo kanthu polimbana ndi zotsatira zoopsa za mankhwala zomwe zingawononge maselo.
Zikuwoneka kuti zili ndi makhalidwe enieni a ubongo, kutanthauza kuti amathandiza kuteteza maselo a ubongo ndi ubongo kuti asawonongeke. Palinso umboni wakuti kukhala ndi vuto la melatonin kumathandizira kuvutika maganizo.
Kafukufuku wina amasonyeza kuti mahomoni amatha kuchepetsa kuvutika maganizo , ngakhale kuti ochita kafukufuku amatsindika kuti zotsatira zake ndi zochepa ndipo kuti melatonin si "mankhwala" a matenda a Alzheimer's. Ochita kafukufuku ena amavomereza kuti mphamvu ya hormoni idzakhala yocheperachepera pa sitepe ya Alzheimer's .
Ochita kafukufuku ayamba kukhala ndi "melatoninergic" kapena mankhwala otchedwa melatonin omwe amagwira nthawi yaitali komanso amakhala ndi zolinga zowonjezereka. Mwachitsanzo, Rozerem (ramelteon) wagonjetsa FDA kuvomereza kwa nthawi yaitali kusokonezeka kwa tulo. Koma pakalipano, palibe mankhwala a mtundu wa melatonin omwe apangidwa makamaka pa matenda a Alzheimer's kapena sundowning.
Pansi
Maphunziro ochuluka a sayansi ayenera kuchitidwa pogwiritsira ntchito supplementation ya melatonin mu matenda a Alzheimers kuti amvetsetse ubwino wake weniweni (kapena ayi).
Koma popeza kuti melatonin imatchulidwa ngati chowonjezera, imapezeka popanda mankhwala. Izi zitanenedwa, musanapereke mankhwala kwa munthu amene ali ndi matenda a Alzheimers, muyenera kumufunsa dokotala yemwe angadziwe ngati ndizomveka.
Zotsatira:
Alzheimer's Association. "Nkhani Zogona ndi Sundowning
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KUDZIZIRANI: Zomwe zili pa tsamba ili ndi zolinga za maphunziro okha. Sitiyenera kugwiritsidwa ntchito ngati choloweza m'malo mwa chisamaliro cha munthu wodwala wovomerezeka. Chonde funsani dokotala wanu kuti apeze matenda ndi chithandizo cha chilichonse chokhudza zizindikiro kapena matenda .