Nutropenia Yowonongeka Kwambiri

Neutropenia yodziwika bwino imafotokoza izi mkhalidwe mwangwiro. Ndikumabereka (kutanthauza kuti wabadwa nawo) chikhalidwe chokhala ndi neutropenia (kutanthauza kuti neutrophil count

Kodi Zizindikiro Ndi Ziti?

Zizindikiro zimayambira posachedwa atangobereka.

Neutrophils ndi mtundu wa selo loyera la magazi lomwe limalimbana ndi matenda a bakiteriya. Kuwerengeka kochepa kwambiri kwa neutrophil kumawonjezera chiopsezo cha matenda opatsirana. Chiwopsezo ndi chizindikiro chofala, koma ndi chifukwa cha matenda osati neutropenia. Ziwalo zoberekera sizikuwoneka.

• Otitis media (matenda a khutu)
• Cellulitis (matenda a khungu)
• Zilonda zakumwa
• Gingivitis (kutupa kutupa)

Kodi Zimapezeka Bwanji?

Zikuoneka kuti nthawi imodzi mwa matendawa, dokotala wanu adzalandira malipiro athunthu (CBC) . Neutropenia yoopsa (<500 maselo / microliter) iyenera kukhala yodwala ya magazi okha. Maselo ofiira a magazi ndi mapiritsi ayenera kukhala achilendo. Kawirikawiri ma monocytes (mtundu wina wa selo woyera wa magazi udzakwezedwa). Ngati mitundu yambiri ya magazi imakhudzidwa, matenda ena (monga Shwachman Diamond Syndrome) ayenera kuganiziridwa.

Kamodzi kowopsa kwambiri kwa neutropenia, dokotala wanu angaganizire kukufikitsani kwa katswiri wamagazi, dokotala wodziwika bwino m'magazi.

Poyamba mukhoza kukhala ndi CBC yomwe imakokera 2 kapena 3 mlungu uliwonse kuti muyambe kuyambitsa matendawa ( neutropenia ) ngati vuto.

Khwerero lotsatira ndi fupa la mafupa. Chiyesochi chimaphatikizapo kuchotsa pang'onopang'ono kachidutswa ka fupa kuti muyese fupa la mafupa, malo omwe maselo oyera amagazi amapangidwa.

Pachimake chochuluka chotchedwa neutropenia, maselo amapangidwa kawirikawiri koma kenako amamwalira asanamasulidwe.

Ngati mafupa anu ali osiyana kwambiri ndi matenda a chiwindi, dokotala wanu angatumize mayesero achibadwa kuti adziwe momwe mutha kusintha. Izi ndi zofunika pamene zidzatsimikizira ngati mungapereke chikhalidwe ichi kwa ana anu kapena momwe mungathere.

Kodi mankhwalawa ndi otani?

• Chojambulira cha Granulocyte Colony (G-CSF kapena filgrastim): G-SCF imaperekedwa monga jekeseni (pansi pa khungu) tsiku lililonse. Mankhwalawa amachititsa kupanga mafupa a mafupa ndi kusasitsa kwa ma neutrophils. Cholinga chake ndi kubweretsa chiwerengero cha neutrophil kuti chizoloŵezi chiteteze matenda.
• Kusakaniza mafupa a mafupa: Kutsegula mafupa a mafupa kungakhale kochepetsera. Izi kawirikawiri zimaganiziridwa kwa anthu omwe alibe yankho labwino kwa G-CSF. Ngati kulandira kokhala mafupa a mchimwene wake ndikofunika kuti awonetsetse kuti alibe njira yowopsya yokhala ndi ubongo wambiri.
• Mankhwala opha tizilombo: Ngati muli ndi ntheropenia yowopsa kwambiri ndipo mukhale ndi malungo, muyenera kupeza chithandizo chamankhwala mwamsanga. Chiwopsezo chingakhale chizindikiro chokha cha matenda aakulu. Ntchito yamagazi iyenera kutumizidwa kuti ipeze chifukwa chothetsera matenda. Panthawiyi mudzaikidwa pa IV (kudzera mu mitsempha) mankhwala opha tizilombo ngati muli ndi matenda.

Kodi Pali Mavuto Ambiri Othawa?

Pochita chithandizo chabwino, chiyembekezo cha moyo kwa anthu omwe ali ndi chiwopsezo chochuluka kwambiri chokhala ndi chiberekero chakhala cholimba kwambiri. Ndili ndi zaka zambiri, muli ndi chiopsezo chowonjezeka cha myelodysplastic syndrome (MDS) ndi khansa ya m'magazi (makamaka yovuta myeloid leukemia) poyerekeza ndi anthu ambiri. Izi zinkangoganiziridwa kuti ndizochiwiri kwa chithandizo cha G-CSF koma zikuwoneka kuti ndizovuta kwa chikhalidwe.

Kuchiza ndi G-CSF kungayambitse splenomegaly (kutsekula kwa mpeni). Nthaŵi zina kuwonjezeka kumeneku kwa nthonje kumapangitsa kuti chiwerengero chochepa chotchedwa platelets (thrombocytopenia) chikhale chochepa. Ngati thrombocytopenia ndi yovuta, mungafunike splenectomy.