Mankhwalawa amachiritsidwa ndi penicillin, mankhwala omwe amagwiritsidwa ntchito pochiza matendawa kuyambira 1943. Ngakhale kuti matenda a bakiteriya amatha kuchiritsidwa ndi mitundu ina ya maantibayotiki, pali nthawi yomwe penicillin ndiyo yokha. Wokondedwa wa munthu yemwe ali ndi kachilomboka angathenso kutetezedwa kuti asateteze ku matenda. Zina osati maantibayotiki, palibe njira ina yothandizira yothetsera matenda a syphilis.
Mankhwala
Chithandizo cha khungu nthawi zambiri amafuna jekeseni imodzi. Njira yothandizira makamaka imayendetsedwa ndi siteji ya matenda (choyamba, chachiwiri, latent, chapamwamba) ndi zina zowonjezera.
Penicillin G imatengedwa ngati mankhwala osankhidwa. Anthu amadwala penicillin , mankhwala ena monga doxycycline, tetracycline, azithromycin, ndi ceftriaxone angagwiritsidwe ntchito. Chinthu chokhacho chingakhale neurosyphilis (kumapeto kwa nthawi yokhudza ubongo ndi pakatikati ya mitsempha) kapena congenital syphilis (kumene matendawa amaperekedwa kuchokera kwa mayi kupita kwa mwana pamene ali ndi mimba) yomwe penicillin ndiyo njira yokhayo.
Nthaŵi zambiri, mankhwalawa adzaperekedwa ndi jekeseni (IM), mwakachetechete. Pa milandu yoopsa, mankhwalawa akhoza kuperekedwa mwachangu (kudzera mwa IV).
Mosiyana ndi matenda ena a bakiteriya amene anthu amachiritsidwa atachiza, anthu omwe ali ndi syphilis ayenera kuyesedwa kuti athe kutsimikizira kuti matendawa atha.
Ngakhale kuti nthawi zambiri munthu saganiziridwa kuti ali ndi kachilombo ka HIV pakatha maola 24 atatha kuchiza, madokotala ena amalimbikitsa kudziletsa mpaka mayesero atsopano atatha.
Malingaliro a Chithandizo
Mu 2015, Centers for Disease Control and Prevention (CDC) inapereka ndondomeko zatsopano zokhudzana ndi chithandizo cha syphilis zomwe zikutsatiridwa lero:
- Tizilombo toyambitsa matenda, pulasitala, kapena oyambirira: Mmodzi wodwala jekeseni wa Benzathine penicillin G
- Kachirombo kameneka kameneka, katemera wosakwanira wa nthawi yosadziwika, kapena syphilis yapamwamba: jekeseni zitatu zamatenda a Benzathine penicillin G anapereka sabata imodzi
- Neurosyphilis kapena chiwindi cha mawanga: Aqueous crystalline penicillin G IV amatsitsa maola anayi alionse masiku 10 mpaka 14, omwe amatha kutsatiridwa ndi jekeseni imodzi ya Benzathine penicillin G; Mankhwala othandizira ndi procaine penicillin G akhoza kuonedwa nthawi zina
Ngakhale kuti penicillin G imayesedwa bwino kwambiri poyeretsa matenda a syphilis, anthu ena angafunike mankhwala ena ngati mayesero atsatizanowu akuwonetseratu kuchepa kwa mphamvu ya mankhwala a syphilis. Kuwonjezera apo, mavuto aakulu a ubongo ndi opangidwa akhoza kugwidwa ndi kupitirira ngakhale atatha kuchipatala.
Zomwe tatchula pamwambazi zapachiyambi, zapakati, zoyambirira, ndi zotsalira za syphilis zimagwiritsidwa ntchito kwa makanda ndi ana, komanso akuluakulu. Chifukwa chakuti nthawi pakati pa matenda oyambirira ndi syphilis yapamwamba ndi yaitali kwambiri (nthawi zambiri zoposa zaka 10 mpaka 20), chithunzithunzi chapamwamba chimakhala chosowa kwambiri mwa ana.
Azimayi Oyembekezera
Chithandizo cha syphilis chomwe chimapezeka pa nthawi ya mimba chimatsatira ndondomeko zomwezo kwa akuluakulu omwe atchulidwa pamwambapa. Komabe, ndi penicillin G okha amene amadziwika kuti ndi othandiza popewera kufalitsa kwa mwana wosabadwa.
Ngati mayi ali ndi vuto la penicillin, dokotala wake amafunika kumukhumudwitsa ndi zovuta zowonjezera . Izi zikutanthauza kuti amaika maiyo ku penicillin ang'onoang'ono ndikuwonjezerapo mlingo pang'ono kuti pakhale kupirira kuti athe kuchitidwa ndi antibiotic.
Zodetsa nkhaŵa
M'zaka zaposachedwapa, pakhala pali nkhaŵa yowonjezereka yowopsa kwa mankhwala osokoneza bongo omwe amachiza matenda opatsirana pogonana.
Zambiri mwazifukwazi zimachokera ku kugwiritsa ntchito mankhwala opatsirana pogwiritsa ntchito mankhwala opatsirana pogonana, zomwe zimachititsa kuti anthu ayambe kutsutsa komanso kusiya njira imodzi ya mapiritsi. Zotsatira zake, gonorrhea masiku ano amachiritsidwa ndi kuphatikiza kwa mankhwala ophera jekeseni ndi olankhula.
Pakalipano, sipanakhale zisonyezero za izi zikuchitika ndi syphilis ndi penicillin. Komabe, pali zizindikiro zotsutsana ndi azithromycin , makamaka zogwirizana ndi mankhwala osakanikirana a syphilis omwe anawonekera koyamba m'ma 1950 ndi kuyamba ma antibiotic.
Choncho, pamene odwala epidemiologist akupitiriza kufufuza kuti adziwe ma antibayotic resistance, penicillin ayenera kuonedwa kuti ndi njira yabwino komanso yodalirika kwambiri yothetsera syphilis.
Ogonana
Ngati mwapezeka kuti muli ndi chiphuphu, okondedwa anu akuyenera kudziwitsidwa ndi kuchiritsidwa, kachiwiri, pa gawo lanu la matenda:
- Ndi chithandizo chachikulu , chidziwitso chiyenera kutumizidwa aliyense yemwe mwakhala mukugonana naye kwa masiku 90 asanaoneke.
- Ndi kachilombo kachisanu , chidziwitso chiyenera kutumizidwa kwa wina aliyense amene wagonana naye kwa miyezi isanu ndi umodzi musanakhale zizindikiro.
- Ndili ndi matenda oyambirira a syphilis , chidziwitso chiyenera kutumizidwa ndi aliyense yemwe wagonana naye chaka chimodzi musanakhale zizindikiro.
Malinga ndi chithandizo chamankhwala, madokotala ambiri amachititsa munthu wina aliyense wogonana naye ngati matenda, chifukwa amatha masiku 90 kuti apeze zotsatira zoyenera . Komabe, ngati chithandizochi chinachitika patatha masiku 90 chizindikiro chikuoneka, dokotala angasankhe kuyesa woyambayo poyamba.
Chifukwa chiopsezo chotenga kachilombo kamachepa mofulumira pambuyo pa chaka choyamba, chidziwitso cha mnzanu chikhoza kapena sichikutsatiridwa. Monga matenda ochiritsidwa , dokotala wanu amafunidwa ndilamulo kuti apereke chidziwitso cha matendawa kwa akuluakulu a zaumoyo; Komabe, dzina lanu silikuphatikizidwa mu lipoti ili.
> Zotsatira:
> Zolinga za Kuletsa ndi Kuteteza Matenda. "2015 Matenda Opatsirana pogonana Njira Zothandizira: Chinyezi." Atlanta, Georgia; zasinthidwa pa June 27, 2017.
> Stamm, L. "Global Challenge ya Treponema pallidum ya Antibiotic-Resistant." Antimicrob Agent Chemo. 2010; 54 (2): 583-589. DOI: 10.1128 / AAC.01095-09.