Chifukwa Choyambira Pakati pa Mlungu Wonse
Mlingo wa methotrexate wa nyamakazi ya nyamakazi ndi zina zotupa za nyamakazi ziyenera kutengedwa mlungu uliwonse, osati tsiku lililonse monga mankhwala ambiri. Chifukwa ndizosiyana ndi nthawi yothandizira mankhwala, zimasokoneza poyamba, kupatula ngati dokotala wanu atenga nthawi kuti afotokoze bwinobwino.
Zolakwitsa zapangidwa ndi odwala amene amaganiza kuti "sabata iliyonse" ndi zolakwika chabe zolemba za bothotrexate mankhwalawa.
Ngati muli ndi kukayikira, itanani dokotala wanu ndikuitana dokotala wanu. Fufuzani kawiri kapena katatu-fufuzani zomwe mukufunikira. Ndikofunika kuti mupeze bwino. Kawirikawiri, Institute of Health Safe Practices imalandira mapepala okhudza kumwa mankhwala ochepetsa kumwa mankhwala chifukwa cha vuto lililonse la tsiku ndi tsiku.
Mlingo wa Mlungu wa Methotrexate
Methotrexate inali mankhwala osokoneza khansa isanavomerezedwe kuti nyamakazi ikhale ndi nyamakazi. Mlingo umene umagwiritsidwa ntchito pa matenda a nyamakazi ndi matenda ena opweteka ndi ochepa poyerekeza ndi omwe amagwiritsidwa ntchito ndi khansa. Kawirikawiri, anthu omwe ali ndi matenda a nyamakazi amalembedwa mapiritsi a 2.5 milligram methotrexate (7,5 milligrams) kuti aziwatenga kamodzi pamlungu, tsiku lomwelo la sabata (mwachitsanzo, Loweruka lirilonse). Ngati pakufunika, dokotala akhoza kuchulukitsa mlingo, koma amatengedwa mlungu uliwonse, osati tsiku lililonse.
Malinga ndi katswiri wa mafupa a zinyama, Scott J. Zashin, MD, "Kutenga methotrexate kamodzi pamlungu kumapereka mphamvu koma kumachepetsa chiopsezo cha kuwonongeka kwa chiwindi ndi mafupa a mafupa." Pali zotsatira zowopsa kwambiri, makamaka hepatoxicity, ngati methotrexate imatengedwa molakwika tsiku ndi tsiku.
Musayambe kuchulukitsa mlingo woyenera wa methotrexate kapena kusintha nthawi yanu.
Mlingo wokwanira wa Methotrexate Mlingo wa Chifuwa cha Matenda a Nyamakazi
Mlingo wachizolowezi wamtundu wa methotrexate wa nyamakazi ya nyamakazi ndi, monga tanenera pamwambapa, 7.5 milligrams ngati mlingo umodzi wa mlungu umodzi. Zingatengedwe ngati mlingo wogawikana: 2.5 milligrams omwe amatchulidwa pakamwa pa maola khumi ndi awiri (12) pa mlingo umodzi pamlungu (mwachitsanzo, 00:00, 12:00, ndi 23:59 tsiku lomwelo).
Mlingo waukulu wa mlungu uliwonse wa mlungu wa mlingo wa mankhwala ovomerezeka ndi ma milligrams 20. Chizoloŵezi chachizolowezi cha ana cha mankhwala cha methotrexate cha nyamakazi ya nyamakazi ndi mamiligalamu 5 mpaka 15 kamodzi pamlungu.
Malingana ndi zotsatira zofufuza zomwe zafalitsidwa mu Annals ya Rheumatic Diseases , mlingo woyenera "umboni" wovomerezeka wa umboni ndi njira zoyendetsera anthu akuluakulu odwala matenda a nyamakazi amayamba ndi mlingo woyambira wa mamiligita 15 oral methotrexate kamodzi kamodzi pamlungu. Mlingo umenewo ukhoza kuwonjezeka ndi milligrams 5 pamwezi pa 25-30 milligrams pa sabata kapena mlingo wokwera kwambiri. Mankhwala otchedwa methotrexate angapangidwe ndi anthu omwe ali ndi nyamakazi ya mafupa omwe amapeza yankho lokwanira ndi methotrexate ya pamlomo kapena kwa iwo omwe sangathe kulekerera malemba. Ziribe kanthu kusintha komwe kumapangidwa, ziyenera kukhala ngati mlingo wa mlungu uliwonse.
Machenjezo Enanso a Methotrexate
Methotrexate ikugwirizana ndi kuwonjezeka kwa poizoni ngati atengedwa ndi mankhwala ena, monga mankhwala osakanikirana ndi anti-inflammatory (NSAIDs) , mankhwala a acid reflux, ndi mankhwala ena oletsa tizilombo. Kugwiritsa ntchito mankhwalawa kungawononge poizoni, komanso ngakhale imfa. Onetsetsani kuti dokotala ali ndi mndandanda wathunthu wa mankhwala omwe mumatenga ndikukambirana momwe mungagwiritsire ntchito ndi methotrexate.
Methotrexate sayenera kutengedwa ndi anthu omwe ali ndi matenda a chiwindi, matenda aakulu a impso, uchidakwa, matenda a magazi (mwachitsanzo, kuchepa kwa magazi , leukopenia) kapena matenda a mafupa. Methotrexate sayenera kugwiritsidwa ntchito ndi amayi omwe ali ndi mimba kapena omwe akuyamwitsa. Iyenso iyenera kuyimitsidwa ndi amayi ndi abambo omwe akukonzekera kutenga mimba.
Ngati mukupeza zizindikiro zowonongeka pamene mukutsata methotrexate, funani thandizo lachipatala. Zizindikiro zoterezi ziphatikizapo ming'oma, kukhudza khungu, kupuma kovuta, kutupa nkhope, milomo, lilime, kapena mmero. Muyenera kusiya mankhwala oterewa ndikuitanitsa dokotala mukakhala ndi chifuwa chouma, kupuma pang'ono, kutsegula m'mimba, kusanza, zofiira zoyera kapena zilonda m'kamwa mwako , magazi mumtsuko kapena chotupa, kupindula mwamsanga, kuchepa kwa mkodzo, kupweteka, malungo, zizindikiro za chimfine, kufooka, kumutu, kapena chizindikiro china chirichonse chachilendo.
Zotsatira zambiri zomwe zimagwirizanitsidwa ndi methotrexate ndi miseche, kumutu, chizungulire, kutopa, ndi masomphenya ophwanyika. Anthu ena omwe amavutika ndi zotsatira zofanana ndi mankhwalawa amatha kupeza njira yowonjezera yowonjezera.
Mawu Ochokera
Methotrexate ikhoza kukhala mankhwala abwino komanso othandiza pa matenda a nyamakazi ngati atengedwa bwino. Iyenera kutengedwa molingana ndi malangizo, popanda kupotoka pazolowera. Musati mutenge zochuluka kuposa zomwe mwalamulidwa ndipo musasinthe ndandanda ya mlungu uliwonse. Dziwani zowopsa, makamaka zovuta kwambiri, ndipo dziwitsani dokotala mwamsanga ngati pali vuto lililonse.
Mudzafunikanso kukhala ndi mayesero a ma laboratory nthawi zonse kuti muwone kuwerengera kwa maselo a magazi, mavitamini a chiwindi , ndi ntchito ya impso . Musamamwe mowa mukamatenga methotrexate. Lolani dokotala wanu kuti adziwe ngati mukudwala matenda opatsirana. Funsani dokotala wanu za kumwa mankhwala opha tizilombo toyambitsa matenda. Ndikofunika kukambirana za katemera ndi dokotala. Anthu omwe ali ndi mlingo waukulu wa methotrexate ayenera kupewa katemera wamoyo. Mfundo yofunika-kuti muteteze kugwiritsa ntchito methotrexate, muyenera kutsatira mosamalitsa malangizo ndi kumvetsera machenjezo ndi zodziletsa. Lankhulani momasuka ndi dokotala wanu za chirichonse chomwe sichidziwika bwino, kapena chirichonse chokhudzana ndi inu.
> Zotsatira:
> Ngakhale Methotrexate Yosavuta Kwambiri Imayambitsa Vuto Kapena Imfa Ngati Ikutengedwa Tsiku Lililonse Kapena ndi Mankhwala Ena. ConsumerMedSafety.org. November 30, 2015.
> Methotrexate. Drugs.com. Adakonzedwanso August 4, 2015.
> Visser K. et al. Mlingo wokwanira ndi Njira Yoyang'anira Methotrexate mu Chifuwa Cha Matenda a Nyamakazi: Kufufuza Kwambiri kwa Mabuku. Annals wa Rheumatic Diseases. July 2009.