Hormone ya antidiuretic, kapena ADH, ndiyo hormone yomwe imapanga mu hypothalamus ndipo imatulutsidwa ndi chigoba cha pituitary. Ntchito yayikulu ndikuteteza kupanikizika kwa magazi, magazi ndi mitsempha ya madzi.
Azimayi omwe ali ndi matenda a polycystic ovarian , kapena PCOS, ali pangozi ya kuthamanga kwa magazi ndipo akhoza kukhala ndi kusiyana kwa ADH.
Katswiri wotchedwa vasopressin, ADH amalimbikitsa kupweteka kwa mitsempha yofewa ndipo amachititsa thupi kusunga madzi, kuteteza kutaya madzi.
Kuchetsa kwa ADH kumachitidwa pamene maselo apadera mu ubongo kapena mtima amadziwa kusintha kwa magazi kapena kuthamanga kwa magazi.
Atatulutsidwa, ADH amapita ku impso kumene imasonyeza maselo enieni kuti abwezeretsenso madzi mumtsuko womwe umasungidwa mu impso, kuteteza madzi kuti asatayike mwa kukodza. Izi zimawonjezera mphamvu ya magazi ndi kuthamanga kwa magazi.
Zotsatira za ADH zosinthika
Mipamwamba ya ADH ingayambitse kusunga madzi. Chinthu chodziwika kuti Syndrome of Inappropriate Anti-Diuretic Hormone (SIADH) chimapangitsa ADH yochuluka kuti ikamasulidwe ngati sikufunika.
Mazinga akuluakulu a ADH angakhale ndi zotsatira za mankhwala ena, kapena amayamba chifukwa cha matenda kapena chotupa m'mapapo, hypothalamus kapena pituitary gland.
Kumwa zakumwa mowa, kumaletsa kumasulidwa kwa ADH, zomwe zimapangitsa kuchuluka kwa mkodzo ndikupanga madzi.
Zizindikiro za kusabvomerezeka kwa ADH zimaphatikizapo kunyoza, kusanza, kupweteka kwa minofu, kusokonezeka ndi kusokonezeka.
Kuyesedwa kwa ADH
Dokotala wanu akhoza kuitanitsa mayeso a ADH ngati muli ndi ludzu lopweteka, nthawi zambiri mumasaka kapena mumadzikayikira , kapena muli ndi magawo osaneneka a sodium. Mayeso angathenso kutchedwa AVP kapena arginine vasopressin.
Kupeza muyeso wolondola wa ADH, komabe, kungakhale kovuta, chifukwa ndi molekyu kakang'ono kwambiri ndi moyo waufupi.
Nthaŵi zina madokotala amagwiritsira ntchito copeptin ngati mankhwala a ADH. Copeptin yakhala ikugwirizanitsidwa ndi matenda a atherosclerosis ndi matenda a mtima, ndipo ingagwiritsidwe ntchito pozindikira matenda a mtima pamayambiriro oyambirira.
ADH ndi Matenda a Mtima
Kafukufuku waposachedwapa wofalitsidwa mu Journal of Ovarian Research anapeza kuti apamwamba amatha kugwira ntchito yofunika kwambiri poyankha magetsi komanso kukula kwa matenda a atherosclerosis mu insulini osagonjetsedwa , amayi oopsa omwe ali ndi PCOS.
Kafukufuku wina anapeza, mwa amayi omwe ali ndi PCOS, magulu othandizira ali oposa odwala kuposa olemera, ndipo amalimbikitsa kuyezetsa magazi kuti aone ngati ali ndi vuto la mtima m'magulu a PCOS.
Zotsatira:
Karbek B, Ozbek M, Karakose M, et al. Copeptin, chizindikiro chodziwika bwino cha arginine vasopressin, amatsutsidwa ndi matenda a mtima kwa odwala polycystic ovary syndrome. J Ovarian Res . 2014 Mar 14; 7:31. lembani: 10.1186 / 1757-2215-7-31.
Taskin MI, Bulbul E, Adali E, Hismiogullari AA, Inceboz U. Kuzungulira maseŵera obestatin komanso kumathandiza amayi omwe ali ovuta komanso osobese ndi matenda a polycystic ovary. Eur J Obstet Gynecol Wotsutsidwa . 2015 Jun; 189: 19-23. lembani: 10.1016 / j.ejogrb.2015.03.006.