Zolemba Zothandizira Kupweteka ndi Kupatsirana Mankhwala Oposa
Kupweteka kwapweteka ndilo cholinga chachikulu cha mankhwala odwala matenda a osteoarthritis. Kutupa komweko, komwe kumachitika ndi osteoarthritis, kumatulutsanso mwakumwa mankhwala opatsirana m'magazi.
Mankhwala osokoneza bongo
Mapuloteni ndi mankhwala omwe amagwiritsidwa ntchito kuti athetse ululu. Zizindikiro zimathandiza kupwetekedwa mtima mwa kulepheretsa zizindikiro zopweteka zomwe zimapita ku ubongo kapena kusokoneza malingaliro a ubongowo, popanda kutulutsa anesthesia kapena kutaya chidziwitso.
Pali mitundu iwiri ya manyowa: osati mankhwala osokoneza bongo komanso mankhwala osokoneza bongo.
Osati mankhwala osokoneza bongo
Acetaminophen ndi mankhwala oyamba operekedwa ndi American College of Rheumatology pofuna kuchiza osteoarthritis, makamaka m'chiuno ndi mawondo. Odwala ena amatha kupeza mankhwala osokoneza bongo (NSAIDs) omwe amatha kupweteka kwambiri kuposa acetaminophen. Pakhala pali maphunziro ndi zokambirana zomwe ziri zothandiza - acetaminophen kapena NSAIDs? Chotsatira ndi chakuti njira za mankhwala zimayenera kukhala payekha.
Zosokoneza Bongo
Nthaŵi zina amatha kupwetekedwa ndi mankhwala osokoneza bongo kwa odwala osteoarthritis omwe aswa mankhwala ena. Ultram (tramadol) sizomwa mankhwala osokoneza bongo koma mankhwalawa ali ndi zowawa zowononga komanso zopweteka. Ultram yatsimikiziridwa kuchepetsa ntchito ya NSAID ndipo imathandiza kuti odwala matenda a osteoarthritis azivutika kwambiri.
Zojambula Zosudzo
Zilonda zamatenda ndi zamtengo wapatali kapena zowonjezera zomwe zimagwiritsidwa ntchito pazowonjezera kunja. Zimagulitsidwa pa-counter-counter. Zosakaniza zowonjezera ndizo:
- Otsutsa - wintergreen mafuta, camphor, eucalyptus
- Salicylates
- Capsaicin
Mankhwala Osakaniza Mankhwala Opanda Matenda (NSAIDs)
NSAID zasonyezedwa kukhala zothandiza kwa osteoarthritis mu maphunziro osiyanasiyana.
Popeza kuti NSAID zambiri zimakhala zofanana mofanana ndi kupumula kwa ululu, chisankho cha NSAID choti chigwiritse ntchito chingakhale chogwirizana ndi mtengo, ndondomeko ya mlingo, ndi chiopsezo cha zotsatirapo. Kuopsa kwa m'mimba komanso poizoni, komanso matenda a mtima, ayenera kuganiziridwa ndi ntchito ya NSAID.
NSAID zikuphatikizapo:
- Ansaid (Flurbiprofen)
- Arthrotec (Diclofenac / Misoprostol)
- Cataflam (potassium ya Diclofenac)
- Clinoril (Sulindac)
- Daypro (Oxaprozin)
- Dolobid (Diflunisal)
- Feldene (Piroxicam)
- Ibuprofen (Motrin, Advil)
- Indocin (Indomethacin)
- Ketoprofen (Orudis, Oruvail)
- Lodine (Etodolac)
- Meclomen (Meclofenamate)
- Mobic (Meloxicam)
- Nalfon (Fenoprofen)
- Naproxen (Naprosyn, Aleve)
- Ponstel (Mefenamic Acid)
- Relafen (Nabumetone)
- Tolectin (Tolmetin)
- Voltaren (Sodium ya Diclofenac)
COX-2 Selective Inhibitors
COX-2 selective inhibitors ali ndi mphamvu zochepetsera m'mimba kuposa NSAID zachikhalidwe. Dokotala wanu ayenera kulingalira zopindulitsa potsata zoopsa ndikuwonanso mtengo pamene mukufuna NSAID yabwino kapena COX-2 inhibitor kwa inu.
NSAID amagwira ntchito poletsa ntchito ya enzyme, cyclooxygenase, yomwe imatchedwanso COX. Kafukufuku wasonyeza kuti pali mitundu iwiri, yotchedwa COX-1 ndi COX-2. NSAID zimakhudza mitundu yonseyi. COX-1 imakhudzidwa ndi kusunga minofu yathanzi, pamene COX-2 ikukhudzidwa ndi kutupa njira.
COX-2 selective inhibitors anakhala a Subsese of NSAIDs, ndipo chisankho chabwino kwa odwala omwe ali pachiopsezo cha m'mimba poizoni.
Panthawi ina, panali atatu COX-2 selective inhibitors pamsika: Celebrex, Vioxx, ndi Bextra. Ngakhale awiri omalizira atachotsedwa pamsika, Celebrex ndiyo yokha COX-2 yokha inhibitor yomwe ilipo.
Majekeseni Odziwika
Odwala nyamakazi ya osteoarthritis omwe amagwiritsidwa ntchito palimodzi kapena kutupa kwadzidzidzi angapindule ndi jekeseni ya corticosteroid ya intra-articular .
Katemera wina wamtunduwu umene ungapindulitse odwala matenda a mitsempha ya knee amaphatikizapo jekeseni yeniyeni ya hyaluronan kapena zochokera (mwachitsanzo, Synvisc, Orthovisc , Hyalgan, Euflexxa, Supartz).
Njirayi imadziwika kuti viscosupplementation.
Zotsatira:
Choyamba pa Rheumatic Diseases. Kopezera 12. Lofalitsidwa ndi Arthritis Foundation. Osteoarthritis Treatment Options. Arthritis Foundation.