Lipoprotein (a), amadziwikanso kuti Lp (a), ndi otsika kwambiri lipoprotein (LDL, kapena "choipa" cholesterol) omwe ali ndi mtundu wina wa mapuloteni, wotchedwa glycoprotein, womangirizidwa kwa iwo. (Dzina la glycoprotein iyi ndi apolipoprotein (a). )
Ofufuza akugwirabe ntchito kuti amvetse lipoprotein (a) ndi njira zomwe zingakhudze thanzi lanu. Komabe, kafukufuku wina akusonyeza kuti kukhala ndi lipoprotein (a) yothamanga kwambiri m'magazi anu kungakuike pangozi yowopsa ya matenda a mtima .
Kodi Lipoprotein (a) Kodi
Kupangidwa mu chiwindi ndiyeno kulowa m'magazi anu, lipoprotein (a) yasonyezedwa kuti imangidwe pansi pa makina amkati a mitsempha. Izi zimathandiza kuti chitukuko cha matenda a atherosclerosis chikhale chonchi, chomwe chimayambitsa matenda a mtima, kupweteka kwa mtima, ndi kupwetekedwa ndi matendawa, polimbikitsa kutupa kwa thupi (redness ndi kutupa) komanso kupanga maselo ofooketsa, omwe amakhala nawo atherosclerotic plaques. Kuphatikiza apo:
- Maseŵera apamwamba a lipoprotein (a) amakhulupirira kuti ndi owopsa kwambiri ku makoma ozungulira pamene mnofu wa munthu wa LDL ("woipa") wa cholesterol umakhalanso wapamwamba.
- Maphunziro apamwamba a lipoprotein (a) awonetsedwa kuti athetse mwayi wopulumuka mwa munthu amene ali ndi vuto la mtima.
Makhalidwe Okhazikika
Zofufuza za magazi m'magulu a lipoprotein (a) amafotokozedwa mu milligrams per deciliter (mg / dL). Mlingo wa 30 mg / dL umaonedwa ngati wabwino. Zomwe zilipo kuposa 30 mg / dL zingasonyeze kuti chiwopsezo cha matenda a mtima chikuwonjezereka mpaka 2 mpaka 3.
Komabe, lipoprotein (a) ndondomeko sizili mbali ya chizoloŵezi choyesa magazi, chomwe chimayambitsa mafuta ambiri m'thupi , LDL, ndi cholesterola cha HDL, ndi triglycerides (mawonekedwe a mafuta omwe amapezeka mthupi lonse). Ndichifukwa chakuti 1) sikokwanira kumadziwika kuti lipoprotein (a) zimakhudza thanzi la mtima ndi 2) zimapezeka pafupifupi 15 peresenti ya anthu ambiri, ndi anthu omwe si a ku Puerto Rico, a Chichewa, ndi a Chijapani omwe ali otsika kwambiri miyezo.
Izi zikuti, pali zinthu zingapo zomwe zingakhale bwino kuyang'ana lipoprotein (a) masitepe. Makamaka, awa ndi pamene munthu ali:
- Matenda a mtima komanso matenda a HDL, LDL, ndi triglycerides
- Mbiri yakale ya banja la matenda a mtima, komanso, yachibadwa HDL, LDL, ndi ma triglyceride
- Kupitiliza maulendo apamwamba a LDL ngakhale kulandira chithandizo chamwano
Kodi Mukuyesera Kuchepetsa Mavuto Anu?
Mwamwayi, chifukwa lipoprotein (a) miyezo imakhudzidwa kwambiri ndi majini anu, zomwe mumakonda-zakudya zabwino, kuchita masewera olimbitsa thupi, komanso (ambiri) mankhwala otsika kwa kolesterolini -sakhala ndi zotsatira zochepetsa. Niacin wasonyeza malonjezo ena mu maphunziro achipatala pofuna kuchepetsa lipoprotein (a) masitepe. Komabe, sizimagwiritsidwa ntchito nthawi zonse.
Ngati mukuyesera kuchepetsa chiopsezo cha matenda a mtima, ndi bwino kuika lipoprotein (a) pa chithandizo cha "mankhwala obwerera m'mbuyo" pakalipano komanso kugwiritsira ntchito njira zochepetsera zifukwa zomwe zimayambitsa matenda a mtima. Monga momwe mukudziwira, izi zimaphatikizapo kuchepetsa kuthamanga kwa magazi ngati kuli kotsika kwambiri, kutsika kwa mkulu wa cholesterol LDL, ndi kukweza cholesterol cha HDL. Kafukufuku wambiri wasonyeza kuti kukonzekera zifukwazi zingathandize kuchepetsa chiopsezo cha matenda a mtima kapena kupwetekedwa mtima.
Zotsatira:
Erquo S, Kaptoge S, Perry PL ndi al. Lipoprotein (a) ndondomeko ndi chiopsezo cha matenda a mtima, kudwala, ndi kufa kwapachilendo. JAMA 2009; 302: 412-423.
Boffa MB, Koschinsky ML, Berglund L. Lipoprotein (a): chowopsa choopsa cha matenda a mtima. Clin Lab Med 2006; 26: 751-772.
"Chidziwitso: LIPA-lipoprotein (a) seramu." Chipatala cha Mayo-Mayo Medical Laboratories (2016).
Kang S. "Kodi lipoprotein (a) ndi chiyani chomwe chimatanthauza kwa inu?" HealthCentral (2008).