Kukhala ndi mitsempha yapamwamba ya cholesterol ya LDL ingakuike pangozi yoyambitsa matenda a mtima. Malangizo amalangiza kuti ma LDL anu akhale pansi pa 100 mg / dL. Komabe, sikuti kokha kukhala ndi LDL ya mitsempha ya cholesterol imaika pachiopsezo cha matenda a mtima, mtundu wa LDL particles ukuyenda m'magazi anu ukhozanso kupanga kusiyana. Diso la LDL lingathe kukhala pakati pa zikuluzikulu ndi zamtundu wazing'ono.
Zing'onozing'ono za LDL particles zimakhala zowonjezereka, zomwe zimawapangitsa kuvulaza thanzi lanu la mtima. Oxidized LDL angapangitse kutupa m'mitsempha yomwe imapereka magazi kwa ziwalo zanu ndi ziwalo zina, motero zimayambitsa matenda a atherosclerosis ndikuwonjezera chiopsezo chanu chokhala ndi matenda a mtima kapena kupwetekedwa mtima.
Fomu ya LDL ya Oxidized?
Madzi ojambulidwa a LDL akuganiziridwa kuti amachitika pamene LDL cholesterol particles mu thupi lanu zimagwira ntchito zowonjezera. LDL yodetsedwayo imakhala yogwira ntchito kwambiri ndi ziwalo zozungulira, zomwe zingapangitse kuwonongeka kwa minofu. Zina mwa zinthu zomwe zimawoneka kuti ziwonjezere kuchuluka kwa LDL zowonjezera ndizo:
- Kugwiritsa ntchito zakudya zomwe zili ndi mafuta ambiri
- Kusuta
- Kudwala matenda a shuga
- Kupezeka ndi matenda opatsirana
Pomwe LDL imakhala yodididwa, imalowa mkati mwachitsulo (endothelium) ya mitsempha iliyonse m'thupi, kuphatikizapo mitsempha yamakono , mitsempha yamakono kapena mitsempha yomwe imapereka miyendo ndi manja ndi magazi.
Pomwepo, imalimbikitsa maselo opweteka, monga macrophages, ndi mapaleletsiti pa malo a chotengera ndikulimbikitsanso kumalo owonongeka. Ma macrophages ambiri, cholesterol ndi zina zamadzimadzi zimayamba kusonkhanitsa pa webusaitiyi, kupanga choyika chomwe chikuyamba kukula.
Pakapita nthawi, izi zikhoza kuchepa - kapena kuchepetsa - kuchuluka kwa magazi omwe amapita kumalo amodzi kapena angapo a thupi. Izi zingachititse kuti munthu akhale ndi thanzi labwino, kuphatikizapo matenda a mtima, matenda a mitsempha, kapena matenda a 'dementia'.
Kodi Mungatani Kuti Mulephere Kupanga Oxidized LDL?
Pali zinthu zambiri zomwe mungachite kuti mutha kupanga mapuloteni a LDL, ndipo ambiri a iwo akuphatikiza kupanga kusintha kochepa pa zizoloŵezi zanu za tsiku ndi tsiku kuti muchepetse cholesterol chanu cha LDL , monga:
- Lekani kusuta.
- Musalole mafuta otengera kuchokera ku zakudya zanu. Chakudya chomwe chimakhala ndi mafuta ophatikizapo zakudya, zakudya zokazinga, mbatata ndi zakudya zina zophikidwa ndi mafuta.
- Onjezerani zipatso ndi ndiwo zamasamba kuti muzidya. Sikuti ali ndi zakudya zambiri zokha ndipo ali ndi mafuta ambiri, amakhalanso ndi antioxidants ndi anti-inflammatory properties zomwe zingathandize kuchepetsa kutayidwa kwa LDL.
- Ngati mwapezeka kuti muli ndi shuga kapena matenda opatsirana , chitani izi. Izi ziphatikizapo kuchepetsa kulemera, kudya wathanzi komanso kuchita masewera olimbitsa thupi. Ngati kusintha kwa moyo sikukuthandizani kuti muchepetse shuga ndi kulemera kwanu, wothandizira zaumoyo wanu angakuuzeni za kumwa mankhwala kuti muwathetse vutoli.
Nthaŵi zina, mungafunike mankhwala kuti muthe kuchepetsa cholesterol yanu. Ena mwa mankhwala otsika kwa kolesterolini, monga statins, amakhalanso ndi anti-inflammatory katundu omwe angachepetse cholesterol yanu ndi kupewa kutupa komwe kumathandiza kukhazikitsa mapangidwe a atherosclerosis.
> Zotsatira:
Gawo Lachitatu la Maphunziro a Mtundu wa Cholesterol (NCEP) Gulu la Atafufuza pa Kuzindikira, Kufufuza, ndi Kuchiza kwa Mwazi Wambiri Wamagazi mu Akuluakulu (PDF), July 2004, National Institutes of Health: National Heart, Lung, ndi Blood Institute.
Dipiro JT, Pharmacotherapy: Njira Yophatikiza Pathophysiological., Edition 9. Maphunziro a McGraw-Hill 2014.
Trpkovic A, Resanovic, Stanimirovic J et al. Oxyidized Low-Density Lipoprotein monga Biomarker ya Matenda a Mtima. Crit Rev Clin Lab Sci 2015; 52: 70-85