Alli ndi dzina la mphamvu yocheperachepera pa tsamba lachitsulo cha dzina lachidziwitso mankhwala osokoneza bongo Xenical (omwe amadziwika ngati orlistat).
Orlistat yapangidwa kuti anthu azaka 18 kapena kupitirira omwe ali olemera kwambiri, ndipo ali ndi BMI (chiwerengero cha mthupi) cha 30 kapena kuposa (oposa), kapena 27-29 (kupitirira muyeso) ndipo ali ndi zinthu zina zoopsa zaumoyo.
Orlistat amagwira ntchito potseka ma enzyme omwe amameta mafuta m'matumbo.
Mankhwalawa amangogwira ntchito m'matumbo anu ndipo apangidwa kuchepetsa pafupifupi 25% mwa mafuta omwe mumadya.
Orlistat yapangidwa kuti igwiritsidwe ntchito mogwirizana ndi kuchita masewera olimbitsa thupi nthawi zonse komanso zakudya zochepa zowonjezera mafuta. Zakudya zopitirira 30 peresenti za chakudya chilichonse zimachokera ku mafuta, izi zimathandiza kuchepetsa kupweteka m'mimba komanso zotsatira zina zoipa. Kudya kwambiri mafuta ndi orlistat kungayambitse kupweteka m'mimba ndi kutsekula m'mimba.
Orlistat ikhoza kukhala yothandiza kwambiri kulemera kwa anthu ena. Wopanga amanena kuti akagwiritsidwa ntchito mogwirizana ndi zakudya zochepa zowonjezera mafuta / mafuta ochepa, akuluakulu amatha kutaya pafupifupi 50 peresenti ya kulemera kwake-makamaka, pa mapaundi awiri omwe mumatayika, mutayika mapaundi atatu pogwiritsa ntchito orlistat.
Kafukufuku wina, komabe, asonyeza kuti ikagwira ntchito, amaletsa zotsatira zolemera zolemera pa mapaundi asanu pachaka, poyerekeza ndi placebo. Anthu ambiri amakhalanso olemera chaka chimodzi atatha kumwa mankhwalawa.
Kafukufuku winanso anapeza kuti zakudya zochepa kwambiri zamagidchadirate zimagwira ntchito monga kuphatikizapo zakudya zokhala ndi mafuta ochepa.
Kuyanjana ndi Chenjezo
Orlistat ikhoza kuyanjana kwa odwala ndi zifukwa zotsatirazi. Ngati muli ndi vuto lililonse la thanzi, muyenera kukambirana za odwala mankhwalawa, musanayambe:
- Matenda a chithokomiro
- Matenda a shuga
- Kuphatikizika kwa mtima
- Matenda a mtima
- Kugonjetsa
SUNAYANKHA kulembetsa ngati:
- Ali kale kulemera kwabwino
- Ali ndi pakati kapena akuyamwitsa
- Khalani ndi vuto ndi kuyamwa kwa chakudya
- Wakhala ndi chiwalo chokhalira, ndi / kapena kutenga Neoral, Sandimmune, Cyclosporine, ndi mankhwala ena osamalidwa bwino.
Zotsatira Zotsatira
Imodzi mwa mavuto akuluakulu a orlistat ndi zotsatira, zomwe zingakhalepo:
- Oles stools
- Maulendo ambiri omwe amapezeka m'mimba
- Zovuta kulamulira kayendedwe ka m'mimba
- Kumva ululu / kusokonezeka
- Kutaya kwa mafuta kuchokera ku anus
- Mafuta amafuta pazovala
- Gasi ndi mafuta odzaza mafuta
- Mutu
- Ululu wammbuyo
- Matenda opatsirana kwambiri
- Kuvutika kwapadera
- Nkhawa
- Kusintha kwa msambo
Zotsatira zoopsa komanso zoopsa zitha kuwonetsa kuwonongeka kwa chiwindi. Aitaneni dokotala mwamsanga mukakumana ndi zizindikiro izi mukamatenga orlistat:
- Mtsinje wakuda
- Fever
- Khungu la Jaundiced kapena maso
- Zovala zamitundu yowala
- Kutaya njala
- Njuchi, zimapitirizabe kuyabwa
- Kutopa kwambiri
- Kufooka
- Kuthamanga
Pazochitika zosayembekezereka za zotsatira zoyipa-zomwe zingaphatikizepo kuvutika kukumeza, kupuma kovuta, kuyabwa kosasintha / ming'oma, kapena kupweteka kwambiri m'mimba / m'mimba-muyenera kuitanitsa 911 kapena kupeza chisamaliro mwamsanga.
Orlistat ndi Thy Thyroid
Mu 2009, a FDA adavomereza kuti mapulogalamu a levothyroxine a sodium (ie, Synthroid, Levoxyl, etc.) asinthidwe kuti asamalidwe ndi orlistat.
Malangizo a Levothyroxine akuphatikizapo chenjezo limene limasonyeza kuti kugwiritsa ntchito orlistat kungachepetse levothyroxine kuyamwa ndi kutsogolera hypothyroidism ndi kuti madokotala amalangizidwa kuti azigwira levothyroxine ndi orlistat maola anayi pambali ndikuchita kafukufuku wokhazikika wa chithokomiro.
Zosintha za Xenical zasinthidwa kuti zisonyeze kugwirizana pakati pa orlistat ndi levothyroxine. Makamaka:
- Pansi pa "Kuphatikizana kwa Mankhwala Osokoneza Bongo," imati "Hypothyroidism yakhala ikudziwika kwa odwala omwe amachiritsidwa mosavuta ndi orlistat ndi levothyroxine"
- Pansi pa "Zochitika Zoipa / Zochitika Zina Zapatala kapena Zomwe Zikuyang'anitsitsa Posakhalitsa," imati: "Hypothyroidism yakhala ikudziwika kwa odwala omwe amachiritsidwa mosavuta ndi orlistat ndi levothyroxine."
- Pansi pa "Ndingathe kutenga XENICAL ndikumwa mankhwala ena?" iwo awonjezera "XENICAL ndi levothyroxine iyenera kutengedwa pafupifupi maola 4 pambali"
Pansi
Ngati muli ndi matenda a chithokomiro mukuyesera kuchepetsa thupi, monga ambiri akukumbukira kuti kulembetsa mankhwala kumakhudzanso kuyamwa kwa mankhwala anu a chithokomiro, ndikukupangitsani kukhala ndi hypothyroid.
Tengani mankhwala anu a chithokomiro osachepera maola 4 kupatula Alli kapena Xenical. Ndipo chitani chithokomiro chanu chiwerengedwe mobwerezabwereza pamene mukugwiritsa ntchito mankhwala, kuti muonetsetse kuti simukuyenera kusintha mlingo wa mankhwala anu a chithokomiro chifukwa cha kuchepetsa kuyamwa.