Pofika kumayambiriro kwa zaka za m'ma 1940, asayansi adawona kuti anthu okhala ndi dzuwa kwambiri amakhala ndi khansa yapakhungu yozama, koma ambiri a khansa. Kwa zaka zambiri, kafukufuku anapeza kusiyana kwa chiwerengero cha khansa 24, ndi khansa yaing'ono m'madera omwe dzuwa limakhalapo.
Masiku ano, n'zoonekeratu kuti mavitamini D ndi omwe amachititsa kuti mitunduyi ikhale yosiyana, ndipo tili ndi umboni wamphamvu wakuti kukhala ndi mavitamini D okwanira kumathandiza kupewa matenda osiyanasiyana a kansa ya khansa, kuphatikizapo matenda a mtima, matenda, komanso matenda osteoporosis.
Kugwirizana pakati pa Vitamin D ndi Khansa ya m'mawere
Mwa amayi omwe ali ndi khansara ya m'mawere , pafupifupi 75 peresenti alibe vitamini D. Amayi omwe ali ndi mavitamini O okwanira a magazi sangathe kupezeka ndi khansara ya m'mawere, ndipo omwe ali ndi khansa ya m'mawere sangathe kupezeka mobwerezabwereza. ngati mavitamini awo a vitamini D ali okwanira. Mu 2014, kufufuza kwa mayesero 56 kunapangitsa kuti vitamini D3 supplementation ikhale ndi kuchepetsa kufala kwa khansa iliyonse.
Vitamini D ikhoza kukhala ndi chitetezo makamaka pa khansa ya m'mawere. Izi zikhoza kuwonjezeka pamene kafukufuku wopitilira amayi opitirira 57,000 am'mbuyo aakazi anapeza kuti amayi omwe adatenga vitamini D zowonjezereka amalephera kuchepetsa chiopsezo cha khansa ya m'mawere. Chomwe chinachititsa chidwi ichi chinali chakuti chinachitika makamaka mwa amayi omwe adagwiritsanso ntchito mankhwala opangira mahomoni .
Kugwiritsidwa ntchito kwa mankhwala opatsirana pogwiritsa ntchito mahomoni ochepa pambuyo pa 2002, pamene phunziro lalikulu, lotchedwa Women's Health Initiative, linaimitsidwa msanga chifukwa cha kuwonjezeka kwa matenda a mtima, kupweteka, ndi khansa ya m'mawere m'gulu lomwe limalandira mankhwala a homoni.
Estrogen imadziwika kuti imalimbikitsa kukula ndi kufalikira kwa maselo a khansa ya m'mawere.
Kuchulukitsa kwa estrogen, chifukwa cha zinthu monga kumayambiriro kwa msambo ndi mafuta owonjezera thupi , zimakhala ndi chiopsezo chachikulu cha khansa ya m'mawere. Vitamini D zowonjezereka zingakhale zotsutsana ndi zotsatira za khansa zomwe zimalimbikitsa mahomoni.
Zinthu zina zomwe zimatsutsa zochita kapena kupanga estrogens zimakhala ndi chiopsezo cha khansa ya m'mawere. Zitsanzo zochepa: bowa zili ndi aromatase inhibitors (aromatase ndi mankhwala omwe amachititsa estrogen); soya ndi fulakesi ndi mbeu za chia zili ndi phytoestrogens zomwe zimayambitsa anti-estrogenic; chakudya chokwanira kwambiri chimapangitsa kuti excretion ya estrogen. Vitamini D ikuwoneka kuti ili ndi zotsatira zofanana.
Malinga ndi momwe mavitamini D amathandizira mavitamini a m'mawere, mavitamini D amagwira ntchito yotulutsa mavitamini, ndipo amachititsa kuti asrogen isachepetse. Vitamini D yasonyezedwanso kuchepetsa chiwerengero cha maselo a estrogen omwe ali ndi khansa ya pachifuwa ya m'mawere, zomwe zimapangitsa maselo kukhala osamvetseka ku zizindikiro za khansa zomwe zimalimbikitsa khansa.
Kodi Kutentha Kwambiri N'kwanira?
Vitamini D yothandizira pakhungu imasiyana pakati pa anthu. Palibe nthawi yeniyeni yowonekera kwa dzuwa yomwe ingagwire ntchito kwa aliyense, ndipo ambiri a ife, kutuluka kwa dzuwa koyenera sikungakhale kokwanira.
Kufufuza kwa anthu okhala ku Hawaii omwe ali ndi kuwala kwa dzuwa - pafupifupi maola 29 pa sabata - pafupifupi 50 peresenti anali ndi mavitamini D omwe anali pansi pa 30 ng / ml. Kuwonjezera apo, enafe timakhala m'madera apamwamba omwe amachititsa kuti Vitamini D akhale ovuta.
Njira yabwino yodziwira kuti ndiyeso yowona magazi (25). Timalimbikitsa kugwiritsa ntchito mankhwala okwanira kuti tipeze malo okoma a 30-45 ng / ml. Kwa anthu ambiri, mlingo wa tsiku ndi tsiku wa vitamini D3 wothandizira (pafupifupi 1000-2000 IU / tsiku) umayenera kufika pawindo la 30-45 ng / ml.
> Zotsatira:
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> Cadeau C, Fournier A, Mesrine S, et al. Kuyanjana pakati pa vitamini D supplementation ndi mankhwala a menopausal omwe amagwiritsa ntchito pa matenda a khansa ya m'mawere: umboni wochokera ku gulu la E3N. Am J Clin Nutr 2015, 102: 966-973.
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