Yendani m'mipata ya pharmacy yanu yapafupi, ndipo mudzawona mitundu yambiri ya antibiotics monga mavitamini, salves, ndi mafuta ( onaninso Neosporin ndi Polysporin). Komabe, chifukwa chakuti mungagule mwachangu mankhwalawa ndi kuwagwiritsa ntchito ad adbitbit sichikutanthauza kuti amagwira ntchito bwino. Kuwonjezera apo, kugwiritsa ntchito kosayenera mankhwala opangira maantibayotiki kungawononge thanzi lachidziŵitso ngati njira yowonjezereka yotsutsana ndi maantibayotiki .
Zonsezi, ma antibayotiki apamwamba ali ndi zochepa zochepa (zogwiritsa ntchito umboni).
Zikodzo
Pogwiritsidwa ntchito pochizira nthendayi, ma antibiotic sayenera kugwiritsidwa ntchito ngati mankhwala okhaokha (monotherapy) kwa miyezi itatu.
Mankhwala osakanizika amatha kupangidwa ndi mankhwala opangira mankhwala monga clindamycin, erythromycin, ndi tetracycline kuwonjezera pa benzoyl peroxide. Pogwiritsidwa ntchito pamodzi. benzoyl peroxide ndi maantibayotiki apamwamba amachepetsa chiopsezo chakuti Propionibacterium acnes (P. acnes) adzatuluka. Zindikirani, P. acnes ndi mabakiteriya omwe amakula pang'ono, omwe amathandiza kuti chitukuko chizikula.
Clindamycin mwina ndi othandiza kwambiri kuposa erythromycin pamene akuchiza ziphuphu za nthawi yaitali. Komanso, clindamycin yathandizidwa kuchepetsa chiwerengero cha ma blackheads (comedones ndi microcomedones) omwe amafanana ndi ma acne. Kuphatikizana ndi kuphatikizidwa ndi peroxide ya benzoyl, clindamycin ikhoza kuphatikizidwanso ndi tretinoin pofuna kuchiza acne.
Mankhwala ena omwe angagwiritsidwe ntchito pochiza achule ali okha kapena osakaniza mankhwala ena ndi dapsone. Chochititsa chidwi n'chakuti dapsone poyamba ankagwiritsidwa ntchito pochiritsa anthu akhate pamene madokotala anaona kuti inachepetsanso ziphuphu. Mosiyana ndi dapsone yamlomo yomwe ingayambitse matenda ochepetsa magazi m'thupi mwa anthu omwe ali ndi vuto la G6PD; Komabe, dapsone yapamwamba imakhala yotetezeka chifukwa sichilowa m'magazi.
Zina mwazimene zimagwiritsidwa ntchito pochizira mavitamini, mankhwala enaake omwe amamenyana ndi mabakiteriya samangoteteza kachilomboka koma amachepetsa kutupa.
Mabala
M'zaka za m'ma 1960 ndi 1970, madokotala adapeza kuti kugwiritsa ntchito mankhwala opatsirana pogwiritsa ntchito mabala opangira opaleshoni kunachepetsa kwambiri chiopsezo cha matenda. Kuwonjezera apo, chilengedwe chaumphawi chomwe chinakhazikitsidwa ndi kugwiritsa ntchito mankhwala opangira maantibayoti amachititsa kuchiritsa. Posachedwapa, umboni wochepa umasonyeza kuti maantibayotiki amachititsa kuti matenda asatuluke. Komabe, ma pharmayi ambiri akugulitsabe mankhwala opatsirana pogwiritsa ntchito lonjezo loti amathandiza kuthana ndi matenda.
Pazifukwa zifukwa ziwiri, kugwiritsa ntchito mankhwala opangira maantibayotiki kungakhale kosaopsa. Choyamba, ma antibayotiki ndi ma antibayotiki ena omwe amagwiritsidwa ntchito ndi chisamaliro cha zilonda zimathandiza kuti mabakiteriya omwe asagwiritsidwe ndi ma antibiotic, makamaka MRSA . Chachiwiri, anthu nthawi zambiri amakhala ndi zizindikiro zotsutsana ndi antibiotic monga neomycin ndi bacitracin. Zomwe zimayambitsa matendawa zimawoneka ngati dermatitis kapena kutupa kwa khungu ndipo zikhoza kuwonjezeredwa ndi kupitiliza kugwiritsa ntchito mankhwala opangira maantibayotiki, omwe nthawi zambiri amachitika ndi chisamaliro cha zilonda.
Zosankha ngati mungagwiritse ntchito mankhwala opangira maantibayotiki kuti musamalidwe ndi zilonda ziyenera kukhala bwino kwa dokotala wanu. Pamapeto pake, mankhwala opangira maantibayotiki amathandiza kwambiri odwala omwe ali ndi zilonda zofanana ndi omwe amadzimva kuti alibe matenda kapena shuga.
Komanso, mabala ochepa opaleshoni opangidwa ndi aseptic amakhala ngati mankhwala a khungu-mankhwala opangira ma antibiotic mwina osatulutsidwa.
Impetigo
Impetigo ndi khungu lofala kapena matenda ofewa omwe amayamba chifukwa cha mabakiteriya a staph kapena strep. M'zaka za m'ma 1980 ndi 1990, ma antibiotic mupirocin ankaonedwa bwino kuposa neomycin kapena polymyxin pochiza impetigo. Masiku ano, chifukwa cha kuwuka kwa MRSA ndi mitundu ina ya mabakiteriya omwe sagonjetsedwa, mupirocin sichigwira ntchito nthawi zambiri impetigo. Ndipotu, ngati muli ndi khungu kapena zofewa, dokotala wanu angakupatseni mankhwala oletsa mankhwala monga Keflex kapena Trimethoprim-Sulfamethoxazole (TMP-SMX) yomwe ikugwirizana ndi MRSA.
Pomalizira, mankhwala opatsirana pogwiritsa ntchito mankhwala ophera mankhwalawa ali ndi mankhwala ochepa kwambiri. Ndibwino kuti, mutagula mankhwala opangira maantibayotiki kuti mudziwe nokha, mwina mukuwononga ndalama zanu. Poipa kwambiri, mukupereka mankhwala osokoneza bongo komanso matenda a khungu.
Zotsatira:
Bhatia A, Maisonneuve JF, Munthu Wokonda DH. PROPIONIBACTERIUM ACNES NDI MAVUTO A CHRONIC. Mu: Forum of Medicine (US) Forum pa Zowopsya Zoopsya; Knobler SL, O'Connor S, Lemon SM, et al., Okonza. Matenda Opatsirana Opatsirana: Kutanthauzira Ubale, Kupititsa patsogolo Kafukufuku, ndi Kuchepetsa Zotsatirapo: Chidule cha zokambirana. Washington (DC): National Academy Press (US); 2004. Zapezeka kuchokera: http://www.ncbi.nlm.nih.gov/books/NBK83685/
Nkhani yotchedwa "Kukonzekera kwa mankhwala opha tizilombo m'matumbo" ndi CR Drucker yofalitsidwa mu Dermatologic Therapy mu 2012.