Maantibayotiki Ena Angayambitse Kutentha Kwambiri Kapena Matenda Ena
Nthawi zina mankhwala opha tizilombo amayenera kuthandizira matenda a bakiteriya. Komabe, nthawi zina, kutenga mankhwala opha tizilombo toyambitsa matenda, matenda a khutu, kapena chibayo akhoza kukhala ndi zotsatira zosayembekezereka komanso zosatha. Kodi ma antibayotiki angayambitse kutsegula m'mimba ndipo n'chifukwa chiyani zimachitika?
N'chifukwa Chiyani Maantibayotiki Amayambitsa Kutsekula m'mimba?
Chinthu choyamba kumvetsa za mabakiteriya m'matupi athu ndikuti si "zoipa." Zomwe zimatiyambitsa matenda opweteka ndi omwe sitikufuna.
Koma kwenikweni, matumbo akulu ali ndi nambala yambiri ya mabakiteriya. Izi ndi mabakiteriya omwe amayenera kuti azikhalapo, ndipo amafunikira kuyamwa bwino. Mabakiteriyawa amawononga chakudya ndikuwathandiza kuchimba. Popanda izo, chimbudzi sichitha bwino.
Maantibayotiki Amapha Mabakiteriya Onse
Antibayotiki sangathe kusiyanitsa mabakiteriya omwe amathandiza thupi ndi mabakiteriya omwe amavulaza thupi-imapha mtundu uliwonse wa mabakiteriya omwe amapeza. Ngati mabakiteriya ena omwe amatha kukhala m'matumbo akuluakulu amatha kufa, mabakiteriya abwino / oipa amawonongeka. Popanda ziweto zonse zopangira digseti, kutsegula m'mimba kapena zotayirira zingakhale zotsatira.
Clostridium difficile: Mtundu Wina wa Mabakiteriya Oipa
Timafuna mabakiteriya opindulitsa m'magazi athu, koma sizikutanthawuza kuti mabakiteriya onse omwe akukhala kumeneko akuchita ntchito zabwino kwa matupi athu. Palinso mabakiteriya owopsa omwe amakhala m'magazi.
Nkhani yabwino ndi yakuti nthawi zambiri, mabakiteriya abwino amabwetsa mabakiteriya owopsa, kusunga zinthu zoipa ndikuziletsa kuti zisapangitse matenda.
Aliyense ali ndi vutoli la mabakiteriya, ndipo nthawi zambiri sadziwa kanthu kalikonse, koma kuti kusintha konse pambuyo pa mankhwala ophera tizilombo kumene mabakiteriya othandizira amaphedwa.
Mu 1% mpaka 2% ya anthu, mtundu umodzi wa mabakiteriya owopsa omwe amakhala mu colon- Clostridium difficile- amayamba kuchulukana ndi kutenga chidebe pambuyo pa mankhwala opha tizilombo. Izi zikhoza kuchititsa mavuto ambiri azachipatala kuphatikizapo:
- Matenda otsekemera a C ovuta
- Colitis (kutukuza kwachilendo kwa koloni)
- Pseudomembranous colitis
- Megacolon yoopsa, yoopsa yowopsa yopaleshoni
Kodi Ndi Ma antibayotiki Angachititse Mavuto?
Mankhwala amtundu uliwonse akhoza kusokoneza zomera mumatumbo akulu ndipo amachititsa kuti mabakiteriya azifa kumeneko. Komabe, si mitundu yonse ya maantibayotiki yomwe imakhala ndi mwayi wowonjezera ku matenda a C difficile . Ngakhale ziri zoona kuti kutenga mankhwala aliwonse othetsa ma antibayotiki kungayambitse matenda a C difficile , pali mankhwala ena omwe amakhala ndi chiopsezo chachikulu kuposa ena.
Mankhwala ophera tizilombo omwe amachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo timene timakhala timene timayambitsa matendawa ndi omwe amapangidwa kuti aphe mabakiteriya osiyanasiyana, omwe ali oyenera, chifukwa ali ndi zotsatira zosiyanasiyana pa mabakiteriya osiyanasiyana, kuphatikizapo abwino. Maantibayotiki omwe amagwirizana kwambiri ndi matenda a C difficile ndi awa:
- ma antibayotiki ambiri (clindamycin, cephalosporins [cephalexin], fluoroquinolones),
- penicillin wambiri (ampicillin, amoxicillin)
Maantibayotiki omwe ali ndi chiopsezo chokwanira ndi awa:
- imipenem
- tetracyclines
- macrolides
- sulfa-trimethoprim
Maantibayotiki omwe ali ndi vuto lalikulu kwambiri ndi awa:
- metronidazole
- vancomycin
- aminoglycosides
- sulfa
- nitrofurantoin
- linezolid
Kodi Thandizo la Probiotics Lingathandize Kutsekula Kumadzi?
Maantibiotiki amapezeka kwambiri m'masitolo akuluakulu komanso malo osungiramo mankhwala osokoneza bongo koma si onse omwe analengedwa mofanana. Zikhoza kukhala ndi mitundu yosiyana ya mabakiteriya ndi ndalama zosiyana, ndipo zimakhala zosavomerezeka, ngakhale pali zinthu zina zodalirika kuposa zina. Kuwonjezera pamenepo, sizinadziwe kuti ndi ziti zomwe zingathandize, kapena ngakhale kuchuluka kwa izo zomwe ziyenera kutengedwa.
Choncho, palibe ndondomeko ya bulangete yokhudzana ndi kumwa maantibiotiki pambuyo pa mankhwala ophera tizilombo. Akuti mwina nthawi zina ma probiotic angathandize, koma sizingakhale zoona nthawi zonse, ndipo mtengo wa mankhwala opatsirana ndi omwe angawonongeke angaganizirenso.
Kwa anthu omwe ali ndi matenda opatsirana (IBD) , makamaka omwe ali ndi ostomy kapena j-pouch , ndikofunika kulankhula ndi gastroenterologist za antibiotic. Mankhwala opha tizilombo akhala akugwirizana ndi IBD, ndipo gastroenterologist angakhale ndi malingaliro onena ngati ma probiotic angakhale othandiza, ndi mtundu uti umene ungagwiritse ntchito.
Mawu Ochokera
Matenda a bakiteriya angafunikire kuwachiritsidwa ndi mankhwala opha tizilombo, ndipo sipangakhale njira yowombera. Kusankhidwa kwa maantibayotiki osagwiritsidwa ntchito sikungapangidwe ngati ayi kapena ali ndi chiopsezo chochepa cha matenda a C difficile , koma makamaka ndibwino kusankha kupha mabakiteriya omwe akuyambitsa matendawa. Kamodzi mankhwala atayamba kale, amayenera kutsirizidwa kuti asamapangitse tizilombo toyambitsa matenda tizilombo toyambitsa matenda.
Ngati muli ndi nkhawa zokhudzana ndi matenda otsekula m'mimba mutatha kumwa maantibayotiki, kambiranani ndi dokotala wanu. Nthawi zina, pamakhala njira zina zomwe maantibayotiki angagwiritse ntchito, koma ziyenera kukhala zogwirizana ndi mabakiteriya omwe akuyambitsa matendawa. Kugwiritsa ntchito maantibiotiki kungakhale njira yowonjezeretsa chigoni ndi mabakiteriya abwino, koma izi ziyenera kukambidwa ndi dokotala, chifukwa kachiwiri, oyenerera ayenera kusankhidwa.
Zotsatira:
> Issa I, Moucari R. "Mapulojekiti othandizira kutsekula m'mimba: Kodi tili ndi chigamulo?" World J Gastroenterol. 2014 Dec 21; 20: 17788-17795.
Sachar DB, Walfish AE. "Clostridium difficile-Indedi Colitis." Merck Manual. Sep 2006.
Schroeder MS. "Clostridium difficile - kutsegula m'mimba." Am Phys Physician . 1 Mar 2005.