Kusakaniza zowawa ziwiri zothandizira
Kawirikawiri, madokotala amayesa kuchepetsa kuperekera kwa polypharmacy kapena kuwonetsera kwa mankhwala owonjezera kapena ovuta. Choncho, ngati mupereka ndi zilonda zomwe zimafuna antibiotic, mudzalandira mankhwala a mtundu wina wa antibiotic osati mankhwala a mitundu ingapo ya maantibayotiki. Koma kodi chitsogozochi chikugwiritsidwa ntchito ku mankhwala opweteka kwambiri, komanso?
Zambiri Zokhudza Kukula kwa Zopuma
Zifukwa zolepheretsa kugwiritsira ntchito polephereka pakati pa madokotala ndizochuluka.
Choyamba, mankhwala omwe mumakhala nawo, amakhala ndi chiopsezo chachikulu chogwiritsira ntchito mankhwala osokoneza bongo. Mankhwala osiyana akhoza kuthandizana m'njira zambiri zoopsa.
Chachiwiri, ngati n'kotheka, dokotala amayesa kupereka mankhwala omwe amachiza matenda ndipo amayamba kumayambitsa matenda. Kawirikawiri nthawi zambiri amatha kufotokozera njira zolepheretsa kuthetsa zizindikiro za matenda m'malo molimbana ndi matendawa.
Chachitatu, monga momwe zimagwiritsira ntchito mankhwala osokoneza bongo, kuperewera kwa poizoni kungawononge thanzi labwino. Mwachindunji, kutenga ma antibiotic ambiri mwakamodzi ndi kusamaliza kafukufuku kumawonjezera mwayi woti mabakiteriya osagwiritsidwa ntchito ndi mankhwala adzafalikira pakati pa anthu ambiri. Mabakiteriya osagwiritsidwa ntchito mankhwala osokoneza bongo ndi nkhani zoipa chifukwa amatsutsa mankhwala ndi maantibayotiki ochiritsira.
Chinthu chimodzi chosiyana ndi chitsogozo chachikulu cha kupewera kwa polypharmacy ndi ntchito yapadera ya mankhwala ena opweteka monga acetaminophen (Tylenol) ndi ibuprofen (Motrin).
Mankhwalawa samasokonezana. Komanso, chithandizo cha ululu ndi chovuta komanso kuphatikiza acetaminophen ndipo ibuprofen ikhoza kuchepetsa kupweteka kwambiri pamene mukupewa mankhwala opioid. Kugwiritsa ntchito mowa mopitirira muyeso kukukula, ndipo panopa tikuvutika kwambiri ndi vuto la opioid.
Zolemba, opioids ndi mankhwala omwe ali ndi zotsatira zoopsa monga kupuma kwa maganizo ndi kuthekera kozunzidwa.
Kuwonjezera pamenepo, mapangidwe ena a opioid monga Vicodin kapena Norco onsewa ndi hydrocodone-acetaminophen, ndipo, motero, atatengedwa ndi Tylenol, ma opioidswa amatha kukhala ndi acetaminophen. Kuchuluka kwa acetaminophen kungawononge chiwindi.
Tylenol
Tylenol ndi mtundu wa analgesic umene umasintha momwe timamverera kupweteka ndikuchepetsa kutentha kwa matupi athu (mwachitsanzo, antipyretic). Nthawi zambiri zimakhala pamodzi ndi mankhwala ena opanga ululu wosiyana.
Ngakhale kuti njira yeniyeni ya Tylenol sichidziwikiratu, timakhulupirira kuti mankhwalawa amagwira ntchito mwa kuletsa cyclo-oxygenase (makamaka COX-2). Chifukwa Tylenol imagwiritsidwa ntchito ndi chiwindi, anthu omwe ali ndi vuto la chiwindi ayenera kupewa mankhwalawa ngati n'kotheka.
Motrin
Motrin ndi mankhwala osakanikirana ndi anti-inflammatory (NSAID), omwe, monga Tylenol, amakhala ndi zotsatira zake pa cyclo-oxygenase motero amaletsa prostaglandin kaphatikizidwe. Prostaglandins amalumikizana ndi ululu, kutupa, ndi malungo.
Kuletsedwa mu prostaglandin kaphatikizidwe kumathandizanso kuti vasoconstriction ndi vuto la chiwerewere likhale ndi vuto la impso. Choncho, anthu omwe ali ndi mavuto a impso ayenera kuchoka pa Motrin.
Mwa zina, Motrin angayambitsenso zilonda zam'mimba ndi kutuluka m'magazi.
Kuphatikiza Awiri
Chochititsa chidwi n'chakuti, ngakhale kuti chizoloŵezi chofala, kafukufuku wochuluka sanachitidwe pofufuza kayendetsedwe ka kayendedwe ka Tylenol ndi Motrin.
Zina mwafukufuku oyambirira pa mutuwo unkachitidwa pa ana. Komabe, ndi zovuta kukoka zolumikizana zenizeni pakati pa kupweteka ndi kupuma kwa malingaliro kwa ana poyerekeza ndi akuluakulu. Mwachindunji, ana omwe atchulidwa onse Tylenol ndi Motrin chifukwa cha ululu ndi malungo amatenga mankhwalawa ngati mankhwala ena.
Zotsatira za kafukufuku wina waung'ono wofalitsidwa ku British Journal of Anesthesia zimasonyeza kuti pamene Tylenol ndi Motrin atengedwa pamodzi (monga mafilimu otchedwa Maxigesic) odwala omwe atangopangidwa opaleshoni yamlomo, kuphatikiza kumeneku kumabweretsa mpumulo wopweteka kwambiri.
Mofananamo, zotsatira za kafukufuku wodzisanthula kufufuza mayesero owonetseredwa mosavuta komanso zofalitsidwa mu Mankhwala Opweteka amasonyeza kuti "kuphatikiza kwa paracetamol [acetaminophen] ndi NSAID zinali zogwira ntchito kuposa paracetamol kapena NSAID yokha mu 85% komanso maphunziro 64, mwachindunji."
Pansi
Kotero zikuwoneka kuti-mosiyana ndi kuphatikiza kwa aspirin ndi Motrin , zomwe zonse NSAID-kutenga acetaminophen ndi ibuprofen pamodzi ndizokhala zotetezeka komanso zothandiza.
Koma musanapereke zosowa zanu zopumula, ndimayankha yankho ili ndi katatu.
Choyamba, ngati muli ndi vuto la chiwindi kapena impso, simuyenera kutenga acetaminophen kapena Motrin (mwachitsanzo, NSAID), motero.
Chachiwiri, analgesics yowonjezereka ngati Tylenol kapena Motrin ndi cholinga chogwiritsira ntchito kanthawi kochepa chabe. Chonde kumbukirani kuti ululu si chizindikiro chokha komanso chizindikiro cha kuvulala kapena matenda. Ngati ululu wanu ukupitirira, muyenera kuwona dokotala.
Chachitatu, mungathe kuwonjezera pa zizindikiro za Tylenol ndi Motrin motero kukhala ndi lingaliro lokwanira kuti mukhale ndi mlingo womwewo wa mankhwala omwe amawunika ndi dokotala.
> Zotsatira:
Borazan NH, Furst DE. Mankhwala Osakaniza Mankhwala Opaka Opaleshoni, Matenda-Kusintha Mankhwala Osakaniza Mankhwala, Mankhwala Osokoneza Bongo, ndi Mankhwala Ogwiritsidwa Ntchito ku Gout. Mu: Katzung BG, Trevor AJ. eds. Basic & Clinical Pharmacology, 13e . New York, NY: Hill ya McGraw; 2015. Idapezeka pa October 11, 2015.
Cliff KS et al. Kuphatikizana ndi Paracetamol (Acetaminophen) ndi Mankhwala Osakaniza Opanda Matenda Osagwiritsiridwa Ntchito: Kuthandizidwa Kwambiri Kogwiritsira Ntchito Zowonongeka kwa Mavuto Othandiza Pogwira Ntchito Zovuta. Kupweteka kwa mankhwala . 2010. > https://doi.org/10.1213/ANE.0b013e3181cf9281
Sungani AF ndi al. Kuphatikizidwa kwa Acetaminophen ndi Ibuprofen chifukwa cha Kupulumutsidwa Kwapweteka Pambuyo Opaleshoni Yamakono mu Akuluakulu: Mayesero Oletsedwa Okhazikika. British Journal of Anesthesia . 2010. https://doi.org/ > 10.1093 / bja / aep338
Olson KR. Mutu 4. Acetaminophen. Mu: Olson KR. eds. Kuchepetsa & Kudyetsa Mankhwala Osokoneza Bongo, 6e . New York, NY: Hill ya McGraw; 2012.