Rash ya Khungu ndi Zizindikiro Zina Chifukwa cha Tarceva (Erlotinib)
Ngati mwakumana ndi mphutsi, khungu louma, kuyabwa, ndi msomali kusintha pamene mutenga Tarceva (erlotinib) simuli nokha. Kwa anthu ena omwe ali ndi khansa ya m'mapapu, mankhwala opatsirana Tarceva (erlotinib,) ndi ena odwala epidermal factor receptor (EGFR), amadzidabwitsa mankhwala m'njira ya anthu omwe ali ndi khansa ya m'mapapo yabwino ya EGFR. Mankhwalawa asintha khalidwe labwino pamene akukhala ndi khansa, kupulumuka, ndipo nthawi zambiri amakhala ndi zotsatira zochepa kuposa mankhwala a chibadwa .
Chotsatira chimodzi, komabe, chasamala kwambiri: mavuto a khungu
Ambiri omwe amagwiritsa ntchito mankhwala a Tarceva (ndi ena EGFR inhibitors) amakhala ndi chiphuphu, ndipo mwachidwi, kuoneka kwa kutukuka kwagwirizanitsidwa ndi kuyankhidwa kwa mankhwala. Popeza mankhwalawa amatengedwa nthawi yaitali, ndikofunika kukambirana za kasamalidwe kake kosasangalatsa ndi oncologist.
(Ngati muli ndi khansara yamapapu, makamaka mapapu adenocarcinoma, onetsetsani kuti dokotala wachita zoyeza za majini .
Kodi Ndi Matenda Otani a Khungu Amene Amagwirizana ndi Tarceva (Erlotinib)?
Matenda omwe anthu amakumana nawo ku Tarceva (ndi ena epidermal growth factor inhibitors) ndi awa:
- Mphuno ya acneiform - Kuphulika uku nthawi zambiri kumafanana ndi acne yomwe imawoneka achinyamata. Kawirikawiri imakhudza nkhope, dera kumbuyo kwa makutu, khosi, thunthu lapamwamba mofanana ndi V, komanso scalp. Kawirikawiri zimakhudza m'munsi kumbuyo, m'mimba, matako, ndi kumtunda ndi m'munsi. Kuthamanga sikuchitika pamanja a manja kapena mapazi. Zomwe zimachititsa kuti thupi lanu lisamamvetse bwino lingakhale losokoneza ngati mukuwerenga zambiri zokhudza kuthamanga uku, koma ziganizo zingapo zosavuta zingathandize. Papule kumangotanthauza chiphuphu pa khungu. Pustule imatanthawuza bump yomwe ikuwoneka kuti ikudzaza kapena ikukuta. Mawu akuti follicular amangotanthauza kuti zilonda za khungu zili pafupi kapena pamutu wa tsitsi.
- Khungu louma (xeroderma)
- Kuyamwa (pruritis)
- Kukoma mtima pamunsi pa chikhomo kapena toenil (paronychia)
Kodi Rash Ndi Yotani?
Anthu ambiri amachiza mankhwala monga Tarceva ali ndi khungu lofewa, makamaka kawirikawiri kamene kamakhala ngati khunyu, ndi khungu louma.
Zotsatira za Khungu Matenda a Tarceva
Matenda a khungu pa epidermal kukula factor receptor inhibitors angakhudze kwambiri maonekedwe ndi moyo wa anthu omwe amamwa mankhwalawa.
Kafukufuku wina anapeza kuti zotsatirazi zimakhudza thanzi, ntchito, maganizo, ndi chikhalidwe cha anthu odwala mankhwalawa. Zidandaulo zambiri zokhudzana ndi zizindikiro zakuthupi, kuphatikizapo kupweteka, kutentha, komanso kukhudzidwa.
Kodi Rash Imachitika Liti Ndipo Ndiyo Nthawi Yanji?
Kuphulika kwa khungu ku Tarceva kawirikawiri kumayamba masabata 1 mpaka 2 chithandizo chitayamba, ali pa masabata awiri kapena atatu odwala atayamba mankhwala, ndipo pang'onopang'ono akhoza kuthetsa kapena kuthera kwathunthu pa miyezi 2 kapena itatu yotsatira. Kudziwa kuti kuthamanga kumawongolera pakapita nthawi kwathandiza anthu ena kuthana ndi zizindikiro.
Kodi Rash Imatanthauza Tarceva Ukugwira Ntchito Yabwino Kwambiri?
Kafukufuku amasonyeza kuti anthu omwe amayamba kupweteketsa mankhwalawa amakhala ndi chiwerengero chabwino choyankhira komanso kukhala ndi moyo wabwino. Chifukwa cha izi, ndipo chifukwa chakuti mankhwalawa amatengedwa nthawi yaitali, ndikofunikira kuti athe kugwira ntchito pochiritsa zizindikiro.
Matenda a khungu okhudzana ndi mankhwala ena a khansa monga chemotherapy ndi mankhwala ochizira matendawa angakhalepo pamodzi ndi omwe akuchokera ku Tarceva ndipo ayenera kuwayang'anitsitsa mosamala ndi odwala.
Kulemera kwa Rash
Mitundu yambiri yamtundu wa rashes chifukwa cha Tarceva nthawi zambiri imasweka m'magulu atatu:
- Wofatsa: Tarceva yofatsa imatanthauzidwa ngati imodzi yomwe ilibe zilonda (malo otseguka) kulira (kukhetsa) kapena matenda. Kawirikawiri anthu amakhala ndi zizindikiro zochepa zokha ndipo sizimasokoneza zochitika zamoyo.
- Zosakaniza: Kuthamanga kwa Tarceva kumakhala kovuta kapena kofala. Kaŵirikaŵiri palibe zilonda, kulira, kapena matenda. Zizindikiro zosavuta zokhudzana ndi kuyabwa komanso chifundo zingakhalepo, koma pali zosokoneza zochepa zomwe zimachitika pa moyo.
- Kuwopsa: Kuphulika kwakukulu kwa Tarceva kumakhala kawirikawiri (kumaphimba nkhope, chapamwamba, ndi kumbuyo) ndipo kawirikawiri zimagwirizanitsidwa ndi zizindikiro zoopsa za kuyabwa ndi chifundo. Zimakhudza kwambiri khalidwe la moyo. Pakhoza kukhala zilonda (zilonda zotseguka) kulira (zivomezi) ndi zizindikiro za matenda ena achikopa monga kufiira, chikasu kapena kubiriwira, ndi malungo.
Kodi Nsalu Zamatenda Zochokera ku Tarceva Zimagwira Ntchito Motani?
Momwe mankhwala anu amathandizidwira adzadalira kuuma kwa chiwombankhanga, komanso zofuna zanu. Ngakhale kuti mphutsi ikufanana ndi ziphuphu, sizitsamba zamadzimadzi, ndipo sizidzayankhidwa ndi mankhwala ambiri a mavitamini.
Tarceva (Erlotinib) Kupewera Rash ndi Daily Care
Gawo loyambalo mu kasamalidwe ndikuteteza: Njira zothandizira kumaphatikizapo kusunga khungu loyera, kupeŵa kutentha kwa dzuwa, ndikugwiritsa ntchito zowonjezera kusungunuka khungu lanu. Njira yabwino yopewera dzuwa ndikuteteza kuwala kwa dzuwa masana, ndipo amagwiritsa ntchito zovala zoteteza, ngati dzuwa limakhala lopanda dzuwa. Kupeza ziphuphuzi ndi mankhwala opangira mafuta kungachititsenso kuti kupsa tsitsi kumapangitsa kuti kupweteka kwa tsitsi kukhale koopsa komanso kuwonjezereka kwambiri. (Fufuzani malangizo awa pa kutetezedwa kwa dzuwa pa chithandizo cha khansa .)
Ndikofunika kuzindikira kuti mankhwala ochiritsira chizindikiro chimodzi chogwirizana ndi Tarceva angawonongeke chizindikiro china ndikuwonekeratu. Mwachitsanzo, zowonjezereka zimathandiza ndi kuuma ndi kuyabwa koma kuipa kwa acne mtundu wa rash.
Tarceva (Erlotinib) Rash Treatments
Kuchiza kwa mphutsi ya Tarceva kumadalira ngati kapena kuthamanga kuli ndi kachilomboka, ndipo kungaphatikizepo zonse zothana ndi vutoli, kapena kusintha ma dose. Zosankhazi zingaphatikizepo:
Mitundu ya mankhwala:
- Mankhwala opatsirana: Mankhwala opha tizilombo monga clindamycin ndi / kapena topical hydrocortisone nthawi zambiri amagwiritsidwa ntchito poyambanso mtundu wa Tarceva. Zofufuza zikuyang'ana kugwiritsa ntchito vitamini K cream, komanso epidermal kukula mafuta mafuta, omwe onse asonyeza lonjezo m'mayesero a zachipatala. Ndikofunika kuti muzindikire kuti ngakhale kuthamanga kukufanana ndi ziphuphu, siziri choncho, ndipo mankhwala ochulukirapo chifukwa cha ziphuphu sizingathandize phokoso.
- Mankhwala ovomerezeka: Ngati mankhwala opatsirana sali okwanira, mankhwala ochiritsira ndi mankhwala osiyanasiyana a tetracycline angagwiritsidwe ntchito. Kafukufuku akuyang'ananso kugwiritsa ntchito mankhwala opatsirana, monga mlomo wa minocycline monga mankhwala opatsirana; inayamba nthawi isanachitike.
Chithandizo cha Rash Okha: Ngati zizindikiro zikuphatikizapo kutupa kofiira yekha popanda zizindikiro za matenda, zimatengedwa ndi steroid, 1% hydrocortisone, kapena 2.5% ngati kutupa kuli koopsa. Pankhani iyi, pali redness koma palibe mitsempha yomwe imasonyeza kuti kachilombo kalipo.
Kuchiza kwa Mpata Wopatsirana: Pamene mphutsi ya Tarceva imakhala yovuta ndi kachilombo koyambitsa matenda a bakiteriya, sikuti imangokhala wofiira koma nthawi zambiri zimakhala ndi zizindikiro za matenda monga ma whiteheads. Ngati zili choncho, mankhwala ayenera kumaphatikizapo ma antibayotiki (oral tetracyclines) komanso gel yamtundu wa clindamycin.
Kusintha kwa mlingo : Pafupifupi 10 peresenti ya anthu amayamba kupweteka kumene kumafuna kusintha kwa mankhwala. Mlingo wokhazikika wa Tarceva ndi 150 mg tsiku lililonse. Oncologist wanu angaganize kuchepetsa mlingo umenewu kwa 100 mg kapena 50 mg tsiku lililonse. Izi zingakhale zoopsa, makamaka ngati mankhwala akukuchitirani bwino. Zingathandize kudziŵa kuti ngakhale ngakhale kuchepa kwambiri kwa Tarceva, komwe kuli 25 mg tsiku ndi tsiku, zakhala zothandiza kuchiza anthu ena ndi khansa ya m'mapapo.
> Zotsatira:
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