Umboni Wotsutsa ndi Kuletsa Kutenga Probiotic kwa Crohn's kapena Ulcerative Colitis
Momwe tizilombo toyambitsa matenda timakhudzira chitukuko cha matenda opatsirana (IBD) ndi nkhani yotentha yokambirana ndi kufufuza. Tizilombo toyambitsa matenda timatanthawuza tizilombo tonse tizilombo toyambitsa matenda. Tizilombo toyambitsa matenda tizilombo toyambitsa matenda makamaka timaphunzira mosiyana ndi matenda a Crohn ndi matenda a zilonda zam'mimba, chifukwa chakuti lingaliro lakuti IBD ndilo kusokonezeka kwa microbiome, kapena kuti IBD imayambitsa chisokonezo.
Potsatira izi ndi lingaliro lakuti ngati microbiome ingakonzedwe, komanso kuti "tizilumikizana bwino" mabakiteriya akhoza kulimbidwa m'magulu, kuti IBD ikhudzidwe kapena kuchitiridwa.
Lowani ma probiotics , omwe ali "mabwenzi" omwe amamwa, mwina mwa kuwadya kapena kutenga chowonjezera. Maantibiotiki ndi okwera mtengo, ndipo kutchuka kwawo kukukulirakulira, koma kodi iwo ndi ofunika kuika ndalama pa IBD? Ndipo zowonjezereka: Satiyang'aniridwa ndi Administration Chakudya ndi Mankhwala, kukweza funso ngati kapena akhoza kuvulaza.
Mfundo zofunikira kukumbukira za kugwiritsa ntchito maantibiobio mu IBD:
- Simunamvetsetse kuti microbiome imakhudzidwa bwanji ndi IBD.
- Maantibiotiki ena akhoza kukhala ogwira ntchito ku IBD, koma kufufuza kwina kumafunikira.
- Mankhwala ena omwe amagulitsidwa malonda awonetsedwa mogwira mtima kwa pouchitis mwa anthu okhala ndi j-pochi.
- Maantibiotiki angakhale okwera mtengo ndipo kupatula ngati kugwiritsiridwa ntchito "kolondola" sikugwiritsidwe ntchito.
- Maantibiotiki angakhale ovulaza kwa anthu omwe afooketsa chitetezo cha mthupi komanso makanda.
- Ma prostrobitic supplements ayenera kugwiritsidwa ntchito pa malangizo a dokotala.
Kodi Microbiome Ndi Chiyani M'madera a IBD?
Zimadziwika kale kuti anthu omwe ali ndi IBD ali ndi mapangidwe osiyana a zamoyo m'maganizo awo kusiyana ndi anthu abwino.
Tizilombo toyambitsa matenda timadziwika bwino kwambiri: Munthu aliyense adzakhala ndi "maonekedwe ake". Ngakhale zili choncho, pali zochitika mu tizilombo toyambitsa matenda zomwe zimapezeka mwa anthu omwe ali ndi IBD omwe atulukira ndi ofufuza. Momwe izi zikukhudzira ndi zizindikiro ndi mankhwala sichidziwikabe. Choncho, zimamveka kuti pali kusintha kwa microbiome kwa munthu yemwe ali ndi IBD koma sichikudziwika momwe izi zimakhudzira IBD ndipo ngati ichi ndi chinthu chomwe chiyenera kuchiritsidwa kapena chingachiritsidwe bwino.
Kodi Maantibiotiki Alibe Vuto?
Pali lingaliro lakuti ma probiotics ndi abwino komanso oyenera ndipo ndi bwino "kuyesa" ndi kuwona momwe izo zikugwirira ntchito, chifukwa palibe zovuta. Nthaŵi zambiri, makamaka kwa anthu achikulire odwala, ma prostbiotics mwina si owopsa. Anthu ambiri amadya ma probiotics mu chakudya chawo tsiku lililonse, makamaka yogurt, kombucha, kapena kefir. Komabe, kwa magulu ena, monga omwe akudwala kwambiri, atha kufooketsa chitetezo cha mthupi, kapena makanda, mwachitsanzo, ma prostrobitic supply akhoza kuvulaza. Zidzakhala zachilendo, koma zotsatira zowonongeka zakhala zikudziwika, makamaka makamaka kwa ana odwala omwe anapatsidwa mankhwala opatsirana.
Popeza sitidziwa kuti ndi zamoyo ziti kapena zowonjezera ziti zomwe zimafunika kuti tizilombo toyambitsa matenda tizisintha bwino, kugwiritsa ntchito maantibiobio mwa anthu omwe akudwala kale kapena okalamba sangakhale otetezeka.
Palibe umboni wokwanira woti udzatsikire pa nkhaniyi mwa njira imodzi, koma mgwirizanowu pafupipafupi ndi wakuti ma probiotics sali opweteka, ndipo dokotala ayenera kufunsidwa asanayambe kuwagwiritsa ntchito.
Mmene Mungadziwire Ngati Probiotic ikugwira ntchito
Kwa anthu ena, kutenga maantibiobiyumu mwina kumayambitsa mpweya ndi kupuma. Kuyambira ndi mlingo wapang'ono ndi kuwonjezeka pang'onopang'ono pa nthawi kungathandize kuchepetsa zotsatirazi. Kusokonezeka kulikonse kapena zotsatira zina ziyenera kuchoka mu sabata kapena awiri. Ngati iwo satero, ndi nthawi yoti awonenso bwinobwino ma probiotic omwe ali ndi dokotala. Zingakhale zovuta kudziwa ngati ma probiotic akugwira ntchito.
Kwa munthu amene ali ndi zotayirira, ngati chitsimikizo chimakhala chokhazikika chomwe chingakhale chitsimikizo chomwe ma probiotic ali othandiza. Koma ngati IBD ikukhululukidwa , ndipo ma probiotic akugwiritsidwa ntchito kukhala motere: ndi zovuta kudziwa ngati ikugwira ntchito. Ichi ndi chimodzi mwa zifukwa zambiri zomwe ndizofunikira kukambitsirana maantibiotiki ndi dokotala komanso kusunga diary yodalirika poyambitsa maantibiobiya atsopano.
Matenda a antibiotic a Crohn's Disease
Mayesero a ma probiotics kwa anthu achikulire amene ali ndi matenda a Crohn kukhululukidwa awonetsa zotsatira zotsatizana ndi mavitamini a probiotic, ngakhale kuti sizikudziwika bwino kuti ndizovuta ziti zomwe zingakhale zothandiza. Kusanthula meta (yomwe ndi pamene ochita kafukufuku amawerenga zotsatira za maphunziro angapo kuti afike pamapeto) mayesero asanu ndi anayi amenewa sankapindulitsa anthu omwe ali ndi matenda a Crohn. Pakhoza kukhala phindu lopangidwa pamene magulu angapo ankagwiritsidwa ntchito palimodzi, makamaka Saccharomyces boulardii , Lactobacillus , ndi VSL # 3 (yomwe ndi chizindikiro cha malonda chomwe chimakhala ndi magulu asanu ndi atatu a bakiteriya).
Komabe, panali mayesero atatu omwe anaphatikizidwa mu kufotokozera kumeneku komwe kunasonyeza "mwayi wapatali" kwa ana okhala ndi matenda a Crohn omwe amathandizidwa ndi ma probiotics. Izi ziyenera kuzindikiridwa kuti izi ndizo mayesero, zomwe zikutanthauza kuti anawo anali pansi pa chisamaliro cha dokotala, kulandira kuyang'anitsitsa, komanso kuti ma probiotics sayenera kugwiritsidwa ntchito kwa ana omwe ali ndi IBD popanda kukambirana ndi dokotala.
Mapulojekiti mu Ulcerative Colitis
Kufufuza kwa meta komwe kunawoneka pa mayesero 18 a ma probiotics kwa odwala omwe ali ndi zilonda zam'mimba zimagwira kuti " Akatswiriwa anapeza kuti mitundu yambiri ya ma probiotics inkawonetsedwa kuti imathandiza kwambiri anthu omwe ali ndi zilonda zam'mimba. Kuwonjezera pa mapulojekiti a Lactobacillus ndi maantibiobiotiki anali othandiza pa matenda a zilonda zam'mimba koma osati mu matenda a Crohn. Kuphatikizana kwa malonda VSL # 3 kunasonyezedwa kukhala kothandiza kwa ulcerative colitis, ndipo pamene kuphatikiza ndi Lactobacillus, nawonetsedwanso kukhala ndi zotsatira kwa ana omwe ali ndi IBD. Tiyeneranso kukumbukira kuti kugwiritsa ntchito maantibiobio kwa anthu omwe ali ndi IBD ayenera kuchitidwa moyang'aniridwa ndi dokotala, makamaka pa ana omwe ali ndi matendawa.
Mapulojekiti a J-nkhuku
Pali gulu limodzi la anthu omwe ali ndi IBD omwe ma probiotics awonetsedwa othandiza, ndipo ndiwo anthu omwe ali ndi j-poch. Kuchita opaleshoni ya J-pouch ndi mtundu wa opaleshoni yomwe yachitidwa kwa anthu omwe ali ndi zilonda zam'londa, ndipo mawuwa ndi ileal pouch-anal anastomosis (IPAA). Pa opaleshoni iyi, coloni imachotsedwa, limodzi ndi gawo kapena rectum yonse. Mbali yomaliza ya m'mimba yaing'ono imapangidwira m'thumba lomwe limatenga malo a rectum ndipo limasunthira pa anus.
Chinthu chimodzi chomwe chingakhale chokhudza j-pouch ndicho chikhalidwe chotchedwa pouchitis , chomwe chimabweretsa zizindikiro za kutsegula m'mimba, malungo, kufulumizitsa, komanso nthawi zina zamagazi. Pouchitis sichimvetsetsedwa bwino, koma pali umboni wina wakuti kugwiritsa ntchito nthawi zonse ma probiotic kungathandize kupewa mvula ya pouchitis. Matenda amodzi a ma probiotics, omwe ali ndi malonda ndi opangidwa ndi kampani imodzi yokha, awerengedwa ndipo zotsatira zimasonyeza kuti zingathandize kuteteza pouchitis kapena kusunga wodwalayo mu chikhululukiro chitatha chitchitis chitachizidwa ndi maantibayotiki. Vutoli ndilokuti ma probiotics ndi okwera mtengo ndipo nthawi zambiri samaphimbidwa ndi inshuwalansi chifukwa amawoneka ngati othandizira osati mankhwala.
Kodi Mapulojekiti Adzakhala "Ochiritsidwa" a IBD?
Ngakhale pali maphunziro ena omwe amasonyeza ubwino wokhala ndi mitundu yina ya maantibiotiki a ma CDA, zotsatira zake sizingakhale zofunikira kuti ziwoneke kuti ndizochiritsidwa. Maantibiotiki angathandize anthu ena omwe ali ndi IBD, koma n'kofunika kuzindikira kuti sangakhale otheka kuti odwala amaletsa kumwa mankhwala a IBD.
Mawu Ochokera
Kugwiritsiridwa ntchito kwa ma probiotics kuchiza IBD kumawoneka kuti akudalira. Komabe, palinso mafunso ambiri oti ayankhidwe, makamaka momwe microbiome imakhudzidwira isanayambike kuti IBD iyambike ndi momwe izo zimasinthira pamene IBD ikuwombera ndipo ikayikira. Pali mitundu yosiyanasiyana yambiri ya tizilombo toyambitsa matenda m'thupi lomwe zimakhala zovuta kupeza mabakiteriya omwe ayenera kugwiritsidwa ntchito kuti asinthe. Ochita kafukufuku akudandaula kuti ndi zovuta zotani zomwe zingakhale zothandiza, koma palinso zina zosadziwika kuposa zomwe zimadziwika m'dera lino. Kufikira pali deta yowonjezera, sizikuwonekeratu komabe omwe angapindule ndi suppbiotic supplement. Ngati mukuyenera kugwiritsa ntchito maantibiotiki ndi zokambirana zomwe ziyenera kuchitika pakati pa dokotala ndi wodwalayo chifukwa ndi lingaliro laumwini. M'malo moyesera "kuwona," dokotala akhoza kupereka malangizo omwe mabakiteriya angapindule nawo.
> Zotsatira:
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